scholarly journals A Rare Etiology of Bilateral Foot Drop: Weight Loss

2020 ◽  
Vol 9 (4) ◽  
pp. 251-254
Author(s):  
Aylin Reyhani ◽  
Nimet Dortcan
Keyword(s):  
Weight Loss ◽  
Foot Drop ◽  
Foot Deformities ◽  
Excessive Weight Loss ◽  
Balanced Diet ◽  
Excessive Weight ◽  
Short Period ◽  
Physiotherapy Programme ◽  
Peroneal Neuropathies

Excessive weight loss especially when it occurs in a short period of time can lead to some neurological problems including peroneal nerve palsy. Foot drop is the most common presentation of peroneal neuropathies and they rarely occur bilaterally at the same time. Herein, we presented a 46-year-old male patient who developed bilateral foot drop after losing 25 kgs. in two months with an intensive weight reduction diet which was advised by a doctor as a therapeutic regimen. The electromyographic study confirmed the bilateral entrapment neuropathy of the peroneal nerves at the fibular necks and these findings could not be attributed to any other factor except the weight loss. After a balanced diet and a physiotherapy programme, he recovered completely. This case highlights an uncommon but a well documented etiology of peroneal neuropathies. Being aware of this complication and close follow-up are important for the prognosis of these patients. Keywords: foot deformities, peroneal neuropathies, weight loss

Treatment of Non-HIV Cryptosporidial Diarrhea with Azithromycin

1995 ◽  
Vol 29 (10) ◽  
pp. 991-993 ◽  
Author(s):  
Robert E Bessette ◽  
Guy W Amsden
Keyword(s):  
High Dose ◽  
Immunocompromised Patients ◽  
Excessive Weight Loss ◽  
The Past ◽  
Excessive Weight ◽  
Case Summary ◽  
Effective Option ◽  
Stool Cultures ◽  
Immunocompetent Patients

Objective: To report a patient with non-HIV-related cryptosporidial diarrhea who was treated effectively with a regimen of high-dose azithromycin therapy. Case Summary: A 42-year-old immunocompetent man contracted cryptosporidiosis from an ailing calf that he had purchased. He finally was admitted to the hospital because of excessive weight loss and profuse diarrhea. The patient was started on a course of high-dose azithromycin therapy and symptoms resolved within 48 hours. Follow-up stool cultures were negative for the parasite. Discussion: Although usually associated with immunocompromised patients, cryptosporidiosis occurs in immunocompetent hosts in a significant portion of the reported cases each year. Although self-limiting in most cases in this population, the disease can be severe at times and require treatment. Paromomycin therapy has been used in the past with good results. Although macrolides have had erratic effects against this parasite in the past, azithromycin (an azalide) demonstrated good efficacy in this patient. Conclusions: Azithromycin has demonstrated that it may be an effective option for the treatment of cryptosporidiosis in immunocompetent patients. Studies involving its use in immunocompromised patients are currently underway.

scholarly journals 39 Early Higher Parenteral Lipid Intake Decreases Extra-Uterine Growth Restriction in Very Low Birth weight Infants: A Randomized Controlled Trial

2020 ◽  
Vol 25 (Supplement_2) ◽  
pp. e15-e16
Author(s):  
Wissam Alburaki ◽  
Belal Alshaikh ◽  
Kamran Yusuf
Keyword(s):  
Weight Loss ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Very Low Birth Weight ◽  
Intervention Group ◽  
Excessive Weight Loss ◽  
Vlbw Infants ◽  
Excessive Weight ◽  
Uterine Growth

Abstract Background Approximately 43-65% of very low birth weight (VLBW) infants develop extra-uterine growth restriction (EUGR). EUGR is associated with a significant increase in the risk of neurodevelopmental impairment. Inadequate early postnatal nutrition results in excessive weight loss that cannot be explained by the physiologic contraction of body water alone. EUGR and postnatal growth failure are usually associated with negative early energy and nitrogen balance in the first week of life. Growth trajectories after initial weight loss have similar slopes regardless of gestational age, which indicates that the early excessive weight loss is a lead cause for EUGR. Objectives To study whether an early and higher parenteral lipid intake in the first week after birth would decrease the percentage of weight loss and subsequently the incidence of EUGR. Design/Methods This was a randomized, open-label, control trial of appropriate-for-gestational age VLBW infants admitted to our level III NICU. Lipid intake in the control group started at 0.5-1 g/kg/day and was increased daily by 0.5-1 g/kg/day until 3 g/kg/day was reached. The intervention group was started on 2 g/kg/day then increased to 3 g/kg/day the following day. Triglyceride levels were measured the day after the start and after each increase in lipid intake. Results Among the 176 infants assessed for eligibility, eighty-three were included in the trial. There were no significant differences between the control and the intervention group in mean gestational age (27.3 ± 2.4 vs. 27.1 ± 2.3 weeks respectively) or birth weight (1011 ± 250 vs. 1019 ± 271 g respectively). Infants in the intervention group were started on lipid earlier (13.8±7.8 vs. 17.5±7.8 h; p=0.03) and had higher cumulative lipid intake in the first 7 days of age (13.5±4.2 vs. 10.9±3.5 g/kg; p=0.004) that led to a protein to energy ratio; closer to the recommended values. Total fluid intake was similar between the two groups. Infants in the intervention group had a lower percentage of weight loss (10.4±3.6 vs. 12.7±4.6; p=0.02). The mean triglyceride level was higher in the intervention group (1.91± 0.79 vs. 1.49±0.54 mmol/L; p= 0.01), however, hypertriglyceridemia was similar between the two groups at 2 and 3 g/kg/day of lipid intake. Enteral energy and protein intake calculated weekly between the time of parenteral nutrition discontinuation and 36 weeks corrected gestational age (CGA) were similar between the 2 groups. EUGR at 36 weeks CGA was significantly lower in the intervention group (38.6% vs. 67.6%; p=0.01). Conclusion In VLBW infants, the provision of an early and higher dose of parenteral lipid in the first week of life results in less weight loss and lower incidence of EUGR.

PP042-SUN EXCESSIVE WEIGHT LOSS/WEIGHT GAIN BEFORE AND AFTER LIVER TRANSPLANTATION

2011 ◽  
Vol 6 (1) ◽  
pp. 39
Author(s):  
L.R. Anastâcio ◽  
E.G. Vilela ◽  
L.G. Ferreira ◽  
H.S. Ribeiro ◽  
A.S. Lima ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Weight Loss ◽  
Weight Gain ◽  
Excessive Weight Loss ◽  
Excessive Weight ◽  
Before And After

Excessive Weight Loss and Food Aversion in Athletes Simulating Anorexia Nervosa

PEDIATRICS ◽  
1980 ◽  
Vol 66 (1) ◽  
pp. 139-142
Author(s):  
Nathan J. Smith
Keyword(s):  
Weight Loss ◽  
Anorexia Nervosa ◽  
Dominant Role ◽  
Sports Participation ◽  
Optimum Level ◽  
Food Aversion ◽  
Excessive Weight Loss ◽  
Excessive Weight ◽  
Large Numbers ◽  
Definition Of

The dominant role of athletic activities in our society and the extent and intensity of sports participation by large numbers of young people create stresses causing a whole new constellation of health problems, both emotional and physical. One such problem is excessive weight loss and food aversion in athletes. The condition is in many ways similar to primary anorexia nervosa as commonly encountered in young women. The athlete avoiding food and experiencing extreme weight loss is most often a male, however, and does not suffer from severe, deep-seated emotional problems. He is typically a serious and outstanding student athlete fearing failure in meeting expectations of admiring coaches, teammates, and parents. The prognosis is excellent under the treatment by an informed, reassuring physician. The athlete's physician should provide a precise definition of optimum level of fatness for given sports participation. Guidance should be given in such a way that the desired level of fatness can be safely achieved, without threatening health and fitness.

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