scholarly journals Itch in Allergic Contact Dermatitis

2021 ◽  
Vol 2 ◽  
Author(s):  
Julien Lambert
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Health Care Systems ◽  
Contact Allergy ◽  
Productivity Loss ◽  
Short Review ◽  
Chronic Itch ◽  
Care Systems ◽  
Huge Impact ◽  
Allergic Contact

Contact dermatitis is a continuous growing environmental and occupational health problem. It results in high costs for health care systems and the economy due to productivity loss. Moreover, it has a huge impact on the quality of life of patients. The immune response to contact allergy is very complex and not totally elucidated. Recently unique pathways preferentially activated by different allergens were identified. As for a lot of chronic itch disorders, antihistamines are ineffective for allergic contact dermatitis, suggesting a non-histaminergic itch. The precise mechanisms that underlie the development of itch in ACD remain poorly defined. This short review addresses the most recent insights in pruritus in ACD, opening perspectives for future therapies.

Nickel Allergy of the Skin and Beyond

2020 ◽  
Vol 20 (7) ◽  
pp. 1003-1009
Author(s):  
Malena Gergovska ◽  
Razvigor Darlenski ◽  
Jana Kazandjieva
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Contact Allergy ◽  
Correct Diagnosis ◽  
Large Population ◽  
Modern World ◽  
Nickel Allergy ◽  
Positive Skin ◽  
Diagnostic Potential ◽  
Allergic Contact

Background: Hypersensitization to nickel is one of the most common contact allergies in the modern world and it is considered to be a major cause of contact dermatitis, especially for hand eczema. Objective: The aim of this paper is to describe many faces of the nickel allergy and to find out different diagnostic, potential strategies for treatment and prevention in hypersensitized patients. A personal clinical experience with practical clinical cases of contact dermatitis to nickel has also been presented. Methods: Electronic databases on this topic was carried out using PubMed-Medline. Results: The literature review identified many articles reporting for nickel contact allergy and pointing the metal as number one allergen in the frequency of positive skin patch test reactions in a large population worldwide. Herein, a summary of the current understanding and evidence on nickel allergy with practical approach and proposed recommendations to the dermatologist, general practitioner, and the allergist were prepared. Conclusions: The prevalence of nickel allergy represents an important socio-economical and health issue. Metal is one of the most common sensitizing agents worldwide. The morbidity due to this metal represents the allergic contact dermatitis and it is constantly growing in many countries. There are also cases of systemic allergic contact dermatitis, where they could be easily misdiagnosed as adverse drug reactions, which lead to delay of the correct diagnosis and inappropriate treatment.

Filaggrin null mutations and association with contact allergy and allergic contact dermatitis: results from a tertiary dermatology clinic

2010 ◽  
Vol 63 (2) ◽  
pp. 89-95 ◽  
Author(s):  
Berit Christina Carlsen ◽  
Jeanne Duus Johansen ◽  
Torkil Menné ◽  
Michael Meldgaard ◽  
Pal B. Szecsi ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Contact Allergy ◽  
Dermatology Clinic ◽  
Allergic Contact

scholarly journals Spinal GRPR and NPRA Contribute to Chronic Itch in a Murine Model of Allergic Contact Dermatitis

2020 ◽  
Vol 140 (9) ◽  
pp. 1856-1866.e7 ◽  
Author(s):  
Xueting Liu ◽  
De Wang ◽  
Yuhuan Wen ◽  
Liping Zeng ◽  
Yangyang Li ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Murine Model ◽  
Chronic Itch ◽  
Allergic Contact

scholarly journals Contact allergy and allergic contact dermatitis caused by lavender: A retrospective study from an Australian clinic

2019 ◽  
Vol 81 (1) ◽  
pp. 37-42 ◽  
Author(s):  
Linda J. Bingham ◽  
Mei M. Tam ◽  
Amanda M. Palmer ◽  
Jennifer L. Cahill ◽  
Rosemary L. Nixon
Keyword(s):  
Retrospective Study ◽  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Contact Allergy ◽  
Allergic Contact

Contact Dermatitis to Personal Sporting Equipment in Youth

2015 ◽  
Vol 20 (4) ◽  
pp. 323-326 ◽  
Author(s):  
Barbara Marzario ◽  
Dianne Burrows ◽  
Sandy Skotnicki
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Testing ◽  
Private Practice ◽  
Contact Allergy ◽  
Raw Material ◽  
Positive Patch Test ◽  
Test Reactions ◽  
Additional Value ◽  
Allergic Contact

Background: Contact dermatitis to personal sporting equipment in youth is poorly studied. Objective: To review the results of patch testing 6 youth to their sporting equipment in a dermatology general private practice from 2006 to 2011. Methods: A retrospective analysis of 6 youth aged 11 to 14 who were evaluated for chronic and persistent dermatitis occurring in relation to sports equipment was conducted. All patients were subjected to epicutaneous (patch) testing, which included some or all of the following: North American Contact Dermatitis Group (NACGD) series, textile series, rubber series, corticosteroid series, and raw material from the patients’ own personal equipment. Results: All cases had 1 or more positive patch test reactions to an allergen within the aforementioned series, and 3 subjects tested positive to their personal equipment in raw form. Conclusions: Allergic contact dermatitis, not irritant, was deemed the relevant cause of chronic dermatitis in 4 of the 6 patients due to positive reactions to epicutaneous tests and/or personal equipment. The utility of testing to patients’ own sporting equipment was shown to be of additional value and should be considered when patch testing for contact allergy to sporting equipment.

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