scholarly journals Advances in Chromodomain Helicase DNA-Binding (CHD) Proteins Regulating Stem Cell Differentiation and Human Diseases

2021 ◽  
Vol 9 ◽  
Author(s):  
Caojie Liu ◽  
Ning Kang ◽  
Yuchen Guo ◽  
Ping Gong
Keyword(s):  
Gene Expression ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Dna Binding ◽  
Cell Fate ◽  
Developmental Disorders ◽  
Regulation Of Gene Expression ◽  
Stem Cell Differentiation ◽  
Human Diseases ◽  
Health Maintenance

Background: Regulation of gene expression is critical for stem cell differentiation, tissue development, and human health maintenance. Recently, epigenetic modifications of histone and chromatin remodeling have been verified as key controllers of gene expression and human diseases.Objective: In this study, we review the role of chromodomain helicase DNA-binding (CHD) proteins in stem cell differentiation, cell fate decision, and several known human developmental disorders and cancers.Conclusion: CHD proteins play a crucial role in stem cell differentiation and human diseases.

scholarly journals Regulation of Gene Expression in Neural Stem Cell Differentiation and Self-Renewal

2015 ◽  
Vol 3 (4) ◽  
pp. 87-98
Author(s):  
Mohammad Reza Hashemzadeh ◽  
Zahra Seyedi ◽  
Mohammad Amin Edalatmanesh ◽  
Samaneh Rafiei ◽  
◽  
...  
Keyword(s):  
Gene Expression ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Neural Stem Cell ◽  
Regulation Of Gene Expression ◽  
Stem Cell Differentiation ◽  
Self Renewal

Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures

2011 ◽  
Vol 251 (2) ◽  
pp. 110-118 ◽  
Author(s):  
Dorien A.M. van Dartel ◽  
Jeroen L.A. Pennings ◽  
Liset J.J. de la Fonteyne ◽  
Karen J.J. Brauers ◽  
Sandra Claessen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Stem Cell Differentiation ◽  
Embryonic Stem Cell Differentiation

scholarly journals Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures

2010 ◽  
Vol 119 (1) ◽  
pp. 126-134 ◽  
Author(s):  
Dorien A. M. van Dartel ◽  
Jeroen L. A. Pennings ◽  
Liset J. J. de la Fonteyne ◽  
Karen J. J. Brauers ◽  
Sandra Claessen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Embryonic Stem Cell ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Embryonic Stem ◽  
Stem Cell Differentiation ◽  
Embryonic Stem Cell Differentiation

Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate

2009 ◽  
Vol 27 (2) ◽  
pp. 93-102 ◽  
Author(s):  
Dorien A.M. van Dartel ◽  
Jeroen L.A. Pennings ◽  
Peter J.M. Hendriksen ◽  
Frederik J. van Schooten ◽  
Aldert H. Piersma
Keyword(s):  
Gene Expression ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Stem Cell Differentiation ◽  
Early Gene ◽  
Embryonic Stem Cell Differentiation ◽  
Early Gene Expression ◽  
Monobutyl Phthalate

scholarly journals Random Monoallelic Gene Expression Increases upon Embryonic Stem Cell Differentiation

2014 ◽  
Vol 28 (4) ◽  
pp. 351-365 ◽  
Author(s):  
Mélanie A. Eckersley-Maslin ◽  
David Thybert ◽  
Jan H. Bergmann ◽  
John C. Marioni ◽  
Paul Flicek ◽  
...  
Keyword(s):  
Gene Expression ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Stem Cell Differentiation ◽  
Embryonic Stem Cell Differentiation

Focusing of Gene Expression as the Basis of Stem Cell Differentiation

2005 ◽  
Vol 14 (6) ◽  
pp. 608-620 ◽  
Author(s):  
Roman M. Salasznyk ◽  
Robert F. Klees ◽  
Aaron M. Westcott ◽  
Scott Vandenberg ◽  
Kristin Bennett ◽  
...  
Keyword(s):  
Gene Expression ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Stem Cell Differentiation

scholarly journals Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics

Physiology ◽  
2018 ◽  
Vol 33 (1) ◽  
pp. 16-25 ◽  
Author(s):  
Lucas R. Smith ◽  
Sangkyun Cho ◽  
Dennis E. Discher
Keyword(s):  
Gene Expression ◽  
Stem Cells ◽  
Extracellular Matrix ◽  
Stem Cell ◽  
Cell Differentiation ◽  
Stem Cell Differentiation ◽  
Cytoskeletal Reorganization ◽  
Tissue Hydration ◽  
Matrix Mechanics

Stem cells mechanosense the stiffness of their microenvironment, which impacts differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix (ECM) stiffness is clearly transduced into gene expression via adhesion and cytoskeleton proteins that tune fates. Cytoskeletal reorganization of ECM can create heterogeneity and influence fates, with fibrosis being one extreme.

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