scholarly journals Feasibility of Transcatheter Caval Valve Implantation to Improve Sleep-Disordered Breathing in Patients With Severe Tricuspid Regurgitation—A Pilot Study

2021 ◽  
Vol 8 ◽  
Author(s):  
Youmeng Wang ◽  
Roberto Fernandes Branco ◽  
Andrea Fietzeck ◽  
Thomas Penzel ◽  
Christoph Schöbel

Transcatheter caval valve implantation (CAVI) has been evaluated as a treatment option for inoperable patients with severe symptomatic tricuspid regurgitation (TR). We studied the effect of CAVI on sleep disorder breathing (SDB) in patients with right heart failure and TR. Twenty right heart failure patients with severe symptomatic TR who underwent portable monitoring of SDB (ApneaLink), echocardiography, cardiopulmonary exercise (CPET), and laboratory testing were enrolled. This was a single-center, nonblinded study. There were no significant changes in sleep variables, echocardiographic parameters, laboratory results, lung function, and CPET after CAVI. In conclusion, these data suggest that CAVI may not have an effect on SDB; however, additional follow-up fully powered studies with appropriate statistical analyses are needed.

2015 ◽  
Vol 51 (3) ◽  
pp. 135
Author(s):  
Young Ae Yang ◽  
Dong Heon Yang ◽  
Hong Nyun Kim ◽  
Sang Hoon Kwon ◽  
Se Young Jang ◽  
...  

2001 ◽  
Vol 280 (1) ◽  
pp. H11-H16 ◽  
Author(s):  
Yuji Ishibashi ◽  
Judith C. Rembert ◽  
Blase A. Carabello ◽  
Shintaro Nemoto ◽  
Masayoshi Hamawaki ◽  
...  

Severe left ventricular volume overloading causes myocardial and cellular contractile dysfunction. Whether this is also true for severe right ventricular volume overloading was unknown. We therefore created severe tricuspid regurgitation percutaneously in seven dogs and then observed them for 3.5–4.0 yr. All five surviving operated dogs had severe tricuspid regurgitation and right heart failure, including massive ascites, but they did not have left heart failure. Right ventricular cardiocytes were isolated from these and from normal dogs, and sarcomere mechanics were assessed via laser diffraction. Right ventricular cardiocytes from the tricuspid regurgitation dogs were 20% longer than control cells, but neither the extent (0.171 ± 0.005 μm) nor the velocity (2.92 ± 0.12 μm/s) of sarcomere shortening differed from controls (0.179 ± 0.005 μm and 3.09 ± 0.11 μm/s, respectively). Thus, despite massive tricuspid regurgitation causing overt right heart failure, intrinsic right ventricular contractile function was normal. This finding for the severely volume-overloaded right ventricle stands in distinct contrast to our finding for the left ventricle severely volume overloaded by mitral regurgitation, wherein intrinsic contractile function is depressed.


2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Michele Dalla Vestra ◽  
Elisabetta Grolla ◽  
Luca Bonanni ◽  
Vittorio Dorrucci ◽  
Fabio Presotto ◽  
...  

The presence of pulsating varicous veins is an uncommon finding, generically attributed to right heart failure. The precise causes of this phenomenon have been poorly defined in the literature. The finding of this infrequent condition is important because it may be a sign of major diseases, often not known. Here we described a 75-year-old woman presented to the Angiology Unit for the presence of bilateral pulsatile swelling in her groin and along both lower limbs. A bedside ultrasound examination showed an arterial like pulsating flow both in the superficial and in the deep veins of the lower limbs due to a severe tricuspid regurgitation not previously known.


2009 ◽  
Vol 17 (1) ◽  
pp. 22 ◽  
Author(s):  
Sun Ho Hwang ◽  
Kyung Hee Hong ◽  
Hyung Min Noh ◽  
Chan Young Park ◽  
Jong Beom Kim ◽  
...  

2012 ◽  
Vol 64 (6) ◽  
pp. 600-602 ◽  
Author(s):  
Maria Bonou ◽  
Konstantinos M. Lampropoulos ◽  
Maria Andriopoulou ◽  
Dimitrios Kotsas ◽  
John Lakoumentas ◽  
...  

2020 ◽  
Vol 41 (Supplement_1) ◽  
Author(s):  
M M Shaikh ◽  
S Aljabri ◽  
S K Nadar

Abstract Aim It is known that the presence of cardiac pacemaker leads across the tricuspid valve (TV) can lead to tricuspid regurgitation (TR). However the clinical implications of this are not known. The aim of this study was to evaluate the progression of TR in patients with pacemaker leads across the TV and assess the clinical effect on Right ventricular function. Methods Patients who had undergone cardiac device implantation (either pacemaker or implantable cardiac defibrillators) in our institution over a 5 years period were identified. Those who had an echo (for any indication) pre and post device implantation were included in this study and their data assessed. Clinical information was obtained from medical records Results A total of 65 patients (mean age 70 + 13 years, 31 (48%) male and 34 (52%)female)  were enrolled in the study. The median follow up after implantation was 12 (12-24) months. At baseline 29 patients had TR before implantation which increased to 51 (78%) during follow up, indicating that 22 patients developed new TR. Of those with pre existing TR,  17 had  worsening of TR by at least one grade. RV function as measured by TAPSE had decreased from 1.87+ 0.44 to 1.68 +0.42 p = 0.002 . Six patients developed RV dilatation during follow up. 18 patients had developed signs of Right heart failure (either breathlessness with raised jugular venous pressure or pedal oedema or both), of which 13 had only new pedal oedema. There was no difference in comorbidities or the percentage of pacing in the groups that had worsening of TR or RV dilatation. Conclusion There is definite worsening or development of new TR in patients with a pacing lead across the TV. This is associated with an increase in the incidence of right heart failure suggesting that this is not benign. However there does not appear to be any specific risk factor identified that is responsible for this. Changes after pacemaker implantation Pre pacemaker Post pacemaker p value Presence of TR (n) 29 51 0.018 RV dilatation(n) 5 11 0.01 TAPSE (mm) 1.87 + 0.44 1.68 + 0.42 0.002 Presence of pedal oedema(n) 5 13 0.01 TR grade grade 0 Grade 1 Grade2 Grade 3 Grade 4 36 9 16 3 0 14 3 31 16 2 0.008 TR- tricuspid regurgition, TAPSE- Tricuspid annular plane systolic excursion; RV- right ventricle


Thyroid ◽  
2006 ◽  
Vol 16 (8) ◽  
pp. 813-814 ◽  
Author(s):  
Jae-Hyeong Park ◽  
Minho Shong ◽  
Jae-Hwan Lee ◽  
Si Wan Choi ◽  
Jin Ok Jeong ◽  
...  

2014 ◽  
Vol 20 (10) ◽  
pp. S208-S209
Author(s):  
Yodo Tamaki ◽  
Yukiko Hayama ◽  
Naoaki Onishi ◽  
Soichiro Enomoto ◽  
Makoto Miyake ◽  
...  

2020 ◽  
Vol 6 (5) ◽  
Author(s):  
Rodrigo Escalante-Armenta ◽  
Miguel Tapia-Sansores ◽  
María Camila Aguirre-Orozco ◽  
Luis Javier Castellanos-Vizcaíno ◽  
Nilda Espinola-Zavaleta

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