scholarly journals Electrical Modelling of In-Vivo Impedance Spectroscopy of Nicotiana tabacum Plants

2021 ◽  
Vol 2 ◽  
Author(s):  
Lee Bar-On ◽  
Umberto Garlando ◽  
Marios Sophocleous ◽  
Aakash Jog ◽  
Paolo Motto Ros ◽  
...  

Electrical impedance spectroscopy has been suggested as a sensing method for plants. Here, a theoretical approach for electrical conduction via the plant stem is presented and validated, linking its living electrical characteristics to its internal structure. An electrical model for the alternating current conduction and the associated impedance in a live plant stem is presented. The model accounts for biological and geometrical attributes. It uses the electrically prevalent coupled transmission line model approach for a simplified description of the complicated vessel structure. It considers the electrode coupling to the plant stem (either Galvanic or Faradic), and accounts for the different interactions of the setup. Then the model is simplified using the lumped element approach. The model is then validated using a four-point probe impedance spectroscopy method, where the probes are galvanically coupled to the stem of Nicotiana tabacum plants. The electrical impedance data was collected continuously and the results exhibit an excellent fitting to the theoretical model, with a fitting error of less than 1.5% for data collected on various days and plants. A parametric evaluation of the fitting corresponds to the proposed physically based model, therefore providing a baseline for future plant sensor design.

2020 ◽  
Author(s):  
Parinaz Abiri ◽  
Yuan Luo ◽  
Zi-Yu Huang ◽  
Mehrdad Roustaei ◽  
Sandra Duarte-Vogel ◽  
...  

AbstractReal-time detection of vulnerable atherosclerotic lesions, characterized by a high content of oxidized low-density lipoprotein (oxLDL)-laden macrophages or foam cells, remains an unmet clinical need. While fractional flow reserve (FFR)-guided revascularization in angiographically intermediate stenoses is utilized to assess hemodynamic significance, in vivo detection of oxLDL-rich plaques may provide a new paradigm for treating metabolically unstable lesions. Herein, we have demonstrated endoluminal mapping of lipid-laden lesions using 3-D electrical impedance spectroscopy-derived impedance tomography (EIT) in a pre-clinical swine model. We performed surgical banding of the right carotid arteries of Yucatan mini-pigs, followed by 16 weeks of high-fat diet, to promote the development of lipid-rich lesions. We implemented an intravascular sensor combining an FFR pressure transducer with a 6-point micro-electrode array for electrical impedance spectroscopy (EIS) measurements. 3-D EIT mapping was achieved using an EIS-based reconstruction algorithm. We demonstrated that EIT mapping corresponds to endoluminal histology for oxLDL-laden lesions. We further used computational models to theoretically predict and validate EIS measurements. Thus, our 3-D EIS-derived EIT provides in vivo detection of metabolically active plaques with the goal of guiding optimal intravascular intervention.One Sentence SummaryThis work demonstrates in vivo mapping of oxidized LDL-laden endolumen by deploying an intravascular dual-sensor to a swine model of atherosclerosis.


Author(s):  
Mulett-Vasquez Edelberto ◽  
Gonzalez-Correa Carlos-Augusto ◽  
Miranda-Mercado David-Alejandro ◽  
Osorio-Chica Mauricio ◽  
Dussan-Lubert Carmen

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