Diagnostic Evaluation of Visual Snow

Introduction: To determine which patients with visual snow (VS) and VS syndrome (VSS) require standard ophthalmologic testing including automated visual field and which patients require further testing such as macular spectral domain optical coherence tomography (SD-OCT), electrophysiology, and neuroimaging.Materials and Methods: We retrospectively reviewed 52 consecutive patients at three institutions with VS and VSS including the University of Alabama, Callahan Eye Hospital, the University of Missouri-Kansas City School of Medicine, and the Little Rock Eye Clinic from the years 2015 to 2021. We collected historical information, examination findings, ophthalmic testing, electrophysiology, and neuroimaging.Results: Of the 52 patients with VS and VSS, eight of the 52 cases met the clinical criteria for VSS. The ages ranged from 7 to 79 years, with a mean age of 25 years (SD = 14.0). There were 22 males and 30 females. Color vision was tested in 51 cases and was normal in 47 cases (92%). A funduscopic exam was performed in all 52 cases and was normal in 46 cases (88%). The macular SD-OCT was normal in all of the 19 cases that it was performed (100%). A Humphrey visual field was performed in 50 cases and was normal in 43 (86%). A visually evoked potential (VEP) was normal in 18 of the 19 cases where it was obtained (95%). The full-field electroretinography (ffERG) was obtained in 28 cases and was normal in 25 (89%). The multifocal electroretinography (mfERG) was normal in 11 of 12 cases (92%). Only four patients accounted for all of the abnormal electrophysiological tests. In the 37 cases that had an MRI, 29 were normal (78%). Only one patient revealed a lesion in the visual pathway (right optic nerve enhancement in an optic neuritis patient).Conclusions: Patients with VS and VSS, if typical in presentation and with normal testing, do not require a workup beyond a thorough history, neuro-ophthalmologic examination, and automated perimetry. If this testing is abnormal, then ancillary testing is required.

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Simulation and optimization of low impact development for mitigating combined sewer overflows associated with climate change

10.32469/10355/73850 ◽

2019 ◽

Author(s):

◽

Ali Shallal

Keyword(s):

Urban Area ◽

Kansas City ◽

Low Impact Development ◽

Combined Sewer Overflows ◽

Sewer System ◽

University Of Missouri ◽

Simulation And Optimization ◽

Time To Peak ◽

Combined Sewer ◽

The University

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Modeling rainfall runoff can help to understand what is happening throughout the system, how can control of water to prevent flood, and how much the quality of runoff can change in urban area. Modeling sewer system help decision maker to indicate best strategy to prevent flooding, reduce runoff pollution, reduce cost of wastewater treatment and determine best suitable LID to an urban area. This dissertation first starting with analysis the complexity of model necessary to get accepted result in term peak flow, runoff volume, numbers of flooding nodes and time to peak. Modeling requirements may lead to system simplification, as in limiting the size of the pipes included in the analyses. Researchers analyzed the combined sewer system of the urbanized Town Fork Creek catchment in Kansas City, Missouri using PCSWMM to assess the potential impact of the simplifications on hydraulic results.

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Breaking News: Utilizing Video Simulations to Improve Educational Leaders' Public Speaking Skills

Journal of Research on Leadership Education ◽

10.1177/194277511100600509 ◽

2011 ◽

Vol 6 (5) ◽

pp. 234-249 ◽

Cited By ~ 6

Author(s):

Jennifer Friend ◽

April Adams ◽

George Curry

Keyword(s):

Educational Leadership ◽

Kansas City ◽

Public Speaking ◽

Educational Leaders ◽

Leadership Preparation ◽

District Leaders ◽

University Of Missouri ◽

Breaking News ◽

The University ◽

Educational Leadership Preparation

This article examines specific uses of video simulations in one educational leadership preparation program to advance future school and district leaders' skills related to public speaking and participation in televised news interviews. One faculty member and two advanced educational leadership candidates share their perspectives of several applications of advanced technologies, including one-on-one video simulations with the instructor and collaborative peer review of video portfolios. Finally, the authors provide links to multimedia examples of these digital artifacts from an advanced educational leadership course, titled Effective Practices: Media, Government & Public Communications, offered at the University of Missouri-Kansas City.

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Reduction, Oxidation and Homologation of Alkenes

Organic Synthesis ◽

10.1093/oso/9780199764549.003.0021 ◽

2011 ◽

Author(s):

Douglass Taber

Keyword(s):

Free Radical ◽

Enzymatic Hydrolysis ◽

Kansas City ◽

Small Scale ◽

University Of Missouri ◽

Radical Process ◽

Practical Procedure ◽

University Of Wisconsin ◽

The University ◽

Hydrolysis Of

Alkenes are usually reduced by catalytic hydrogenation. Diimide reduction is a mild and neutral alternative. Keith R. Buszek, now at the University of Missouri, Kansas City, has shown (J. Org. Chem. 2007, 72, 3125) that the reduction can conveniently be carried out on resin-bound alkenes, using 2-NBSH (o-nitrobenzenesulfonylhydrazide) with Et3 N for convenient room temperature diimide generation. Ozone can be difficult to dispense accurately on small scale. Masahito Ochiai of the University of Tokushima has uncovered (J. Am. Chem. Soc. 2007, 129, 2772) an alternative, using acid-promoted Ph-I=O. Isolated alkenes also work well. MCPBA is the reagent most commonly used for alkene epoxidation. Payne oxidation (H2O2 /CH3CN) is a convenient and inexpensive alternative. In the course of a study of the enantioselective enzymatic hydrolysis of 6, Takeshi Sugai of Keio University has described (Tetrahedron Lett. 2007, 48, 979) a practical procedure for multigram Payne epoxidation of 5. Several procedures have been put forward for functionalizing terminal alkenes, exemplified by 7. Stefan Grimme and Armido Studer of the Universität Münster have developed (J. Am. Chem. Soc. 2007, 129, 4498) a free radical alkene amination, represented by the conversion of 7 to 9. Tehshik P. Yoon of the University of Wisconsin has found (J. Am. Chem. Soc. 2007, 129, 1866) that Cu catalyzes the addition of oxaziridines such as 10 to alkenes, to make 11. Shinji Nakamura of the University of Tokyo and Masanobu Uchiyama of the University of Tokyo and RIKEN have established (J. Am. Chem. Soc. 2007, 129, 28) that the anion from Cu promoted addition of the silyl zinc reagent to alkenes is long-lived enough to be trapped by electrophiles, including H+ to give 12. Hideki Yorimitsu and Koichiro Oshima of Kyoto University have developed (J. Am. Chem. Soc. 2007, 129, 6094) a complementary transformation, Ni-catalyzed addition of 13 to give 14. The conversion of 7 to 15 reported (Organic Lett. 2007, 9, 53) by Li-Biao Han of the National Institute of Advanced Industrial Science and Technology, Tsukuba, is likely also a free-radical process.

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Relationship between visual field changes and optical coherence tomography measurements in advanced open-angle glaucoma

Folia Medica ◽

10.1515/folmed-2016-0027 ◽

2016 ◽

Vol 58 (3) ◽

pp. 174-181 ◽

Cited By ~ 2

Author(s):

Snezhina S. Kostianeva ◽

Marieta I. Konareva-Kostianeva ◽

Marin A. Atanassov

Keyword(s):

Optical Coherence Tomography ◽

Visual Field ◽

Structural Changes ◽

Open Angle Glaucoma ◽

Mean Deviation ◽

Ganglion Cell Complex ◽

Automated Perimetry ◽

Optical Coherence ◽

Open Angle ◽

Sd Oct

Abstract Aim: To assess relationships between functional changes in visual field and structural changes in advanced open-angle glaucoma (OAG) found using spectral-domain optical coherence tomography (SD-OCT). Methods: Thirty-one eyes of 25 patients with OAG were included in this study. Besides the routine ophthalmological exam the patients underwent standard automated perimetry (SAP) (Humphrey Field Analyzer) and SD-OCT (RTVue–100) performed within 6 months. The global perimetric indices in the study group were as follows: mean deviation (MD) 12.33±6.18 dB and pattern standard deviation (PSD) 9.17±3.41 dB. The relationship between OCT measurements and MD and PSD was evaluated by correlation analysis (Pearson’s correlation coefficient) and regression analysis (linear and nonlinear regression models). Results: Thickness measurements of the lower halves of ganglion cell complex (GCC) and retinal nerve fiber layer by two scanning protocols (ONH and 3.45) showed these to be thinner than the upper halves, but the difference failed to reach statistical significance. The correlations between global indices MD/PSD and most of the analysed quantitative OCT measurements were moderate (r in the range between 0.3 and 0.6). The correlation between MD and GCC showed nonlinear cubic regression (R2=0.417, P=0.004). Good correlation was found between MD and GLV (R2=0.383; P=0.008). Linear regression (P<0.05) was found only between MD and Cup area (R2=0.175, P=0.024) and between MD and RNFL by 3.45 protocol (R2=0.131, P=0.045). Conclusion: Nonlinear regressive models appear to be more appropriate in the assessment of the correlations between functional and structural changes in eyes with advanced glaucoma. The correlations we found were moderate.

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The University of Missouri-Kansas City School of Medicine

JAMA ◽

10.1001/jama.1983.03340040027012 ◽

1983 ◽

Vol 250 (4) ◽

pp. 483

Author(s):

E. Grey Dimond

Keyword(s):

Kansas City ◽

University Of Missouri ◽

City School ◽

School Of Medicine ◽

The University

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Visual Defects Associated with Vigabatrin: A Study of Epileptic Argentine Patients

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/s0317167100004443 ◽

2005 ◽

Vol 32 (4) ◽

pp. 459-464 ◽

Cited By ~ 5

Author(s):

María Cecilia Moreno ◽

Brenda Giagante ◽

Patricia Saidon ◽

Silvia Kochen ◽

Jorge Benozzi ◽

...

Keyword(s):

Visual Field ◽

Antiepileptic Drug ◽

Screening Test ◽

Screening Strategy ◽

Visual Field Defects ◽

Automated Perimetry ◽

Field Screening ◽

Full Field ◽

Visual Defects ◽

Field Defects

ABSTRACT:Objective:The aim of the present study was to assess visual alterations in a population of Argentine patients treated with the antiepileptic drug vigabatrin.Methods:Twenty patients receiving vigabatrin and 15 patients receiving carbamazepine were examined with automated perimetry using a Humphrey 120-point full screening strategy. In addition, scotopic flash electroretinograms were performed.Results:Of 20 patients treated with vigabatrin, two were unable to cooperate with testing. Of the remaining 18 patients, all but two showed at least one non-detected point inside the central 40° of the visual field of each eye. Of the 15 carbamazepine-treated patients, three were unable to perform the study. None of the remaining 12 patients showed visual field defects. Both a- and b-wave amplitudes of the scotopic electroretinogram were significantly reduced in 12 patients receiving vigabatrin.Conclusions:Visual field defects among patients on vigabatrin therapy may occur with a higher frequency than previously recognized. The Humphrey 120-points full field screening test and electroretinography are useful tools to assess the visual dysfunction associated with vigabatrin.

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Curricular Integration at the University of Missouri—Kansas City School of Medicine

Perceptual and Motor Skills ◽

10.2466/pms.1993.76.1.35 ◽

1993 ◽

Vol 76 (1) ◽

pp. 35-40 ◽

Cited By ~ 3

Author(s):

Louise Arnold ◽

T. Lee Willoughby

Keyword(s):

Kansas City ◽

Clinical Medicine ◽

Curricular Integration ◽

University Of Missouri ◽

City School ◽

Clinical Exposure ◽

School Of Medicine ◽

Advanced Students ◽

The University ◽

Interdisciplinary Integration

In its combined Baccalaureate-M.D. degree program, the University of Missouri—Kansas City School of Medicine endeavors to foster interdisciplinary integration by intertwining the humanities, clinical medicine, and basic sciences throughout the curriculum. Analysis over 6 years (1986–1991) of 547 students' scores on comprehensive examinations and ratings of 464 to 478 graduates' clinical abilities suggest that the integrative elements of the curriculum have a counterpart in performance. Such experience would recommend possible steps to encourage interdisciplinary integration at other schools: allow students to acquire disciplinary understandings but offer early clinical exposure for context and relevance, arrange productive repetition of material, pair more with less advanced students for integrated learning, and choose faculty who model integration and expect students to do so.

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