Neurosteroids as Selective Inhibitors of Glycine Receptor Activity: Structure-Activity Relationship Study on Endogenous Androstanes and Androstenes

Frontiers in Molecular Neuroscience ◽

10.3389/fnmol.2020.00044 ◽

2020 ◽

Vol 13 ◽

Author(s):

Julia V. Bukanova ◽

Elena I. Solntseva ◽

Eva Kudova

Keyword(s):

Glycine Receptor ◽

Structure Activity Relationship ◽

Receptor Activity ◽

Activity Relationship ◽

Selective Inhibitors ◽

Structure Activity ◽

Activity Structure ◽

Relationship Study

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Synthesis, biological activity, structure activity relationship study and liposomal formulation development of some arylsulfonyl pyroglutamic acid derivatives

Journal of Molecular Structure ◽

10.1016/j.molstruc.2021.131512 ◽

2021 ◽

pp. 131512

Author(s):

Sanjib Das ◽

Sk. Abdul Amin ◽

Sanchita Datta ◽

Nilanjan Adhikari ◽

Tarun Jha

Keyword(s):

Biological Activity ◽

Structure Activity Relationship ◽

Pyroglutamic Acid ◽

Liposomal Formulation ◽

Activity Relationship ◽

Formulation Development ◽

Structure Activity ◽

Activity Structure ◽

Relationship Study

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Identification and Structure–Activity Relationship Study of Imidazo[1,2-a]pyridine-3-amines as First Selective Inhibitors of Excitatory Amino Acid Transporter Subtype 3 (EAAT3)

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.9b00447 ◽

2019 ◽

Vol 10 (10) ◽

pp. 4414-4429

Author(s):

Peng Wu ◽

Walden E. Bjørn-Yoshimoto ◽

Markus Staudt ◽

Anders A. Jensen ◽

Lennart Bunch

Keyword(s):

Excitatory Amino Acid ◽

Structure Activity Relationship ◽

Amino Acid Transporter ◽

Activity Relationship ◽

Selective Inhibitors ◽

Excitatory Amino Acid Transporter ◽

Structure Activity ◽

Relationship Study ◽

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Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.02.020 ◽

2016 ◽

Vol 112 ◽

pp. 280-288 ◽

Author(s):

Li-Wei Zou ◽

Yao-Guang Li ◽

Ping Wang ◽

Kun Zhou ◽

Jie Hou ◽

...

Keyword(s):

Structure Activity Relationship ◽

Glycyrrhetinic Acid ◽

Activity Relationship ◽

Selective Inhibitors ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

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Identification of selective inhibitors of sphingosine kinases 1 and 2 through a structure–activity relationship study of 4- epi -jaspine B

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.03.059 ◽

2017 ◽

Vol 25 (12) ◽

pp. 3046-3052 ◽

Author(s):

Hiroaki Ohno ◽

Maho Honda ◽

Naoka Hamada ◽

Jun Miyagaki ◽

Akira Iwata ◽

...

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Structure Activity ◽

Sphingosine Kinases ◽

Relationship Study ◽

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Structure–Activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase

ChemMedChem ◽

10.1002/cmdc.201200520 ◽

2013 ◽

Vol 8 (2) ◽

pp. 297-312 ◽

Author(s):

Tsui‐Fen Chou ◽

Kelin Li ◽

Kevin J. Frankowski ◽

Frank J. Schoenen ◽

Raymond J. Deshaies

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Structure Activity ◽

Relationship Study

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Synthesis and Structure-Activity Relationship Study of 2-Substituted- 5-(5-nitro-2-thienyl)-1,3,4-thiadiazoles as Anti-Helicobacter pylori Agents

Letters in Drug Design & Discovery ◽

10.2174/157018009789057599 ◽

2009 ◽

Vol 6 (6) ◽

pp. 468-474 ◽

Author(s):

Alireza Foroumadi ◽

Somayeh Sedaghat ◽

Saeed Emami ◽

Maryam Yazdanian ◽

Mohammad Moshafi ◽

...

Keyword(s):

Helicobacter Pylori ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study

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Structure-activity relationship study on the bioreduction of AZO dyes byClostridium paraputrificum

Environmental Toxicology and Chemistry ◽

10.1002/etc.5620200304 ◽

2001 ◽

Vol 20 (3) ◽

pp. 479-484

Author(s):

David Moir ◽

Sheila Masson ◽

Ih Chu

Keyword(s):

Azo Dyes ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study

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Synthesis and preliminary structure-activity relationship study of 3-methylquinazolinone derivatives as EGFR inhibitors with enhanced antiproliferative activities against tumour cells

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2021.1933466 ◽

2021 ◽

Vol 36 (1) ◽

pp. 1205-1216

Author(s):

Yan Zhang ◽

Qin Wang ◽

Luolan Li ◽

Yi Le ◽

Li Liu ◽

...

Keyword(s):

Structure Activity Relationship ◽

Tumour Cells ◽

Egfr Inhibitors ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study ◽

Antiproliferative Activities

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Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113291 ◽

2021 ◽

pp. 113291

Author(s):

Peng Li ◽

Ying Liu ◽

Hua Yang ◽

Hong-Min Liu

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

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Structure–Activity Relationship Study and Biological Evaluation of 2-(Disubstituted phenyl)-indole-5-propanoic Acid Derivatives as GPR40 Full Agonists

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.1c00031 ◽

2021 ◽

Vol 64 (7) ◽

pp. 4130-4149

Author(s):

Xiaodi Zhao ◽

Dong-Oh Yoon ◽

Jaeho Yoo ◽

Hyun-Ju Park

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Propanoic Acid ◽

Structure Activity ◽

Relationship Study

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