The Atypical Protein Kinase C Small Molecule Inhibitor ζ-Stat, and Its Effects on Invasion Through Decreases in PKC-ζ Protein Expression

Frontiers in Oncology ◽

10.3389/fonc.2020.00209 ◽

2020 ◽

Vol 10 ◽

Author(s):

Tracess Smalley ◽

Rainer Metcalf ◽

Rekha Patel ◽

S. M. Anisul Islam ◽

Raja Reddy Bommareddy ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Protein Expression ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Molecule Inhibitor ◽

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A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion

10.18632/oncotarget.3812 ◽

2015 ◽

Vol 6 (17) ◽

pp. 15297-15310 ◽

Author(s):

Amanda M. Butler ◽

Michele L. Scotti Buzhardt ◽

Eda Erdogan ◽

Shuhua Li ◽

Kristin S. Inman ◽

...

Keyword(s):

Pancreatic Cancer ◽

Protein Kinase C ◽

Protein Kinase ◽

Cancer Cell ◽

Small Molecule ◽

Pancreatic Cancer Cell ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Molecule Inhibitor

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Differential roles of an atypical protein kinase C, PKC ζ, on regulation of human eosinophil and neutrophil functions

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2004.12.777 ◽

2005 ◽

Vol 115 (2) ◽

pp. S191

Author(s):

M. Kato ◽

T. Yamaguchi ◽

A. Tachibana ◽

Y. Hayashi ◽

H. Kimura

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Atypical Protein Kinase C ◽

Human Eosinophil ◽

Atypical Protein Kinase ◽

Kinase C ◽

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Abstract A280: Small molecule inhibition of atypical protein kinase C iota reveals a functional basis for oncogenesis.

10.1158/1535-7163.targ-13-a280 ◽

2013 ◽

Author(s):

Mark Linch ◽

Marta Sanz-Garcia ◽

Svend Kjaer ◽

Erika Soriano ◽

Philippe Riou ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Small Molecule ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Functional Basis ◽

Small Molecule Inhibition ◽

Kinase C ◽

Protein Kinase C Iota

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Differential Role of an Atypical Protein Kinase C, PKC ζ, in Regulation of Human Eosinophil and Neutrophil Functions

International Archives of Allergy and Immunology ◽

10.1159/000085429 ◽

2005 ◽

Vol 137 (1) ◽

pp. 27-34 ◽

Author(s):

Masahiko Kato ◽

Takafumi Yamaguchi ◽

Atsushi Tachibana ◽

Hirokazu Kimura

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Atypical Protein Kinase C ◽

Human Eosinophil ◽

Atypical Protein Kinase ◽

Kinase C ◽

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1222 Identification and characterisation of small molecule inhibitors of atypical protein kinase C (aPKC) as anti-cancer agents

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(09)70434-3 ◽

2009 ◽

Vol 7 (2) ◽

pp. 127

Author(s):

C. Barton ◽

C. Soudy ◽

E. Wynne ◽

B. Patel ◽

S. Kaye ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

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Faculty Opinions recommendation of Atypical protein kinase C-zeta is essential for delayed phagocytosis of Helicobacter pylori.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004446.161957 ◽

2002 ◽

Author(s):

David Underhill

Keyword(s):

Helicobacter Pylori ◽

Protein Kinase C ◽

Protein Kinase ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Protein Kinase C Zeta

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Faculty Opinions recommendation of The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002435.25855 ◽

2001 ◽

Author(s):

Eamonn Maher

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Tumor Suppressor ◽

Tumor Suppressor Protein ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Von Hippel Lindau ◽

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Faculty Opinions recommendation of Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1089955.543122 ◽

2008 ◽

Author(s):

Mark Hargreaves

Keyword(s):

Skeletal Muscle ◽

Protein Kinase C ◽

Protein Kinase ◽

Human Skeletal Muscle ◽

Insulin Signalling ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Peptide Elongation

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Faculty Opinions recommendation of GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717988280.793472704 ◽

2013 ◽

Author(s):

David Wotton

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

Basal Cell Carcinomas

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Faculty Opinions recommendation of Overexpression of atypical protein kinase C in HeLa cells facilitates macropinocytosis via Src activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718295550.793495175 ◽

2014 ◽

Author(s):

Vladimir Marshansky

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Atypical Protein Kinase C ◽

Atypical Protein Kinase ◽

Kinase C ◽

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