scholarly journals Effects of Multiple Filters on Liver Tumor Segmentation From CT Images

2021 ◽  
Vol 11 ◽  
Author(s):  
Vi Thi-Tuong Vo ◽  
Hyung-Jeong Yang ◽  
Guee-Sang Lee ◽  
Sae-Ryung Kang ◽  
Soo-Hyung Kim
Keyword(s):  
Liver Tumor ◽  
Natural Variation ◽  
Liver Tumors ◽  
Ct Images ◽  
Tumor Segmentation ◽  
Hounsfield Units ◽  
Multiple Features ◽  
High Frequencies ◽  
Liver Tumor Segmentation ◽  
Boundary Distance

Segmentation of liver tumors from Computerized Tomography (CT) images remains a challenge due to the natural variation in tumor shape and structure as well as the noise in CT images. A key assumption is that the performance of liver tumor segmentation depends on the characteristics of multiple features extracted from multiple filters. In this paper, we design an enhanced approach based on a two-class (liver, tumor) convolutional neural network that discriminates tumor as well as liver from CT images. First, the contrast and intensity values in CT images are adjusted and high frequencies are removed using Hounsfield units (HU) filtering and standardization. Then, the liver tumor is segmented from entire images with multiple filter U-net (MFU-net). Finally, a quantitative analysis is carried out to evaluate the segmentation results using three different methods: boundary-distance-based metrics, size-based metrics, and overlap-based metrics. The proposed method is validated on CT images from the 3Dircadb and LiTS dataset. The results demonstrate that the multiple filters are useful for extracting local and global feature simultaneously, minimizing the boundary distance errors, and our approach demonstrates better performance in heterogeneous tumor regions of CT images.

scholarly journals Adaptive Attention Convolutional Neural Network for Liver Tumor Segmentation

2021 ◽  
Vol 11 ◽  
Author(s):  
Shunyao Luan ◽  
Xudong Xue ◽  
Yi Ding ◽  
Wei Wei ◽  
Benpeng Zhu
Keyword(s):  
Neural Network ◽  
Liver Tumor ◽  
Semantic Information ◽  
Liver Tumors ◽  
Ct Images ◽  
Attention Mechanism ◽  
Tumor Segmentation ◽  
Expansion Path ◽  
Liver Tumor Segmentation ◽  
End To End

PurposeAccurate segmentation of liver and liver tumors is critical for radiotherapy. Liver tumor segmentation, however, remains a difficult and relevant problem in the field of medical image processing because of the various factors like complex and variable location, size, and shape of liver tumors, low contrast between tumors and normal tissues, and blurred or difficult-to-define lesion boundaries. In this paper, we proposed a neural network (S-Net) that can incorporate attention mechanisms to end-to-end segmentation of liver tumors from CT images.MethodsFirst, this study adopted a classical coding-decoding structure to realize end-to-end segmentation. Next, we introduced an attention mechanism between the contraction path and the expansion path so that the network could encode a longer range of semantic information in the local features and find the corresponding relationship between different channels. Then, we introduced long-hop connections between the layers of the contraction path and the expansion path, so that the semantic information extracted in both paths could be fused. Finally, the application of closed operation was used to dissipate the narrow interruptions and long, thin divide. This eliminated small cavities and produced a noise reduction effect.ResultsIn this paper, we used the MICCAI 2017 liver tumor segmentation (LiTS) challenge dataset, 3DIRCADb dataset and doctors’ manual contours of Hubei Cancer Hospital dataset to test the network architecture. We calculated the Dice Global (DG) score, Dice per Case (DC) score, volumetric overlap error (VOE), average symmetric surface distance (ASSD), and root mean square error (RMSE) to evaluate the accuracy of the architecture for liver tumor segmentation. The segmentation DG for tumor was found to be 0.7555, DC was 0.613, VOE was 0.413, ASSD was 1.186 and RMSE was 1.804. For a small tumor, DG was 0.3246 and DC was 0.3082. For a large tumor, DG was 0.7819 and DC was 0.7632.ConclusionS-Net obtained more semantic information with the introduction of an attention mechanism and long jump connection. Experimental results showed that this method effectively improved the effect of tumor recognition in CT images and could be applied to assist doctors in clinical treatment.

scholarly journals 3D Liver Tumor Segmentation in CT Images Using Improved Fuzzy C-Means and Graph Cuts

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Weiwei Wu ◽  
Shuicai Wu ◽  
Zhuhuang Zhou ◽  
Rui Zhang ◽  
Yanhua Zhang
Keyword(s):  
Liver Tumor ◽  
Processing Time ◽  
Spatial Information ◽  
Liver Tumors ◽  
Graph Cuts ◽  
Ct Images ◽  
Tumor Segmentation ◽  
Dice Similarity Coefficient ◽  
Seed Point ◽  
Liver Tumor Segmentation

Three-dimensional (3D) liver tumor segmentation from Computed Tomography (CT) images is a prerequisite for computer-aided diagnosis, treatment planning, and monitoring of liver cancer. Despite many years of research, 3D liver tumor segmentation remains a challenging task. In this paper, an efficient semiautomatic method was proposed for liver tumor segmentation in CT volumes based on improved fuzzy C-means (FCM) and graph cuts. With a single seed point, the tumor volume of interest (VOI) was extracted using confidence connected region growing algorithm to reduce computational cost. Then, initial foreground/background regions were labeled automatically, and a kernelized FCM with spatial information was incorporated in graph cuts segmentation to increase segmentation accuracy. The proposed method was evaluated on the public clinical dataset (3Dircadb), which included 15 CT volumes consisting of various sizes of liver tumors. We achieved an average volumetric overlap error (VOE) of 29.04% and Dice similarity coefficient (DICE) of 0.83, with an average processing time of 45 s per tumor. The experimental results showed that the proposed method was accurate for 3D liver tumor segmentation with a reduction of processing time.

scholarly journals 3D IFPN: Improved Feature Pyramid Network for Automatic Segmentation of Gastric Tumor

2021 ◽  
Vol 11 ◽  
Author(s):  
Haimei Li ◽  
Bing Liu ◽  
Yongtao Zhang ◽  
Chao Fu ◽  
Xiaowei Han ◽  
...  
Keyword(s):  
Liver Tumor ◽  
Feature Fusion ◽  
Automatic Segmentation ◽  
Ct Images ◽  
Learning Ability ◽  
Gastric Tumor ◽  
Tumor Segmentation ◽  
Gastric Tumors ◽  
Multi Level ◽  
Liver Tumor Segmentation

Automatic segmentation of gastric tumor not only provides image-guided clinical diagnosis but also assists radiologists to read images and improve the diagnostic accuracy. However, due to the inhomogeneous intensity distribution of gastric tumors in CT scans, the ambiguous/missing boundaries, and the highly variable shapes of gastric tumors, it is quite challenging to develop an automatic solution. This study designs a novel 3D improved feature pyramidal network (3D IFPN) to automatically segment gastric tumors in computed tomography (CT) images. To meet the challenges of this extremely difficult task, the proposed 3D IFPN makes full use of the complementary information within the low and high layers of deep convolutional neural networks, which is equipped with three types of feature enhancement modules: 3D adaptive spatial feature fusion (ASFF) module, single-level feature refinement (SLFR) module, and multi-level feature refinement (MLFR) module. The 3D ASFF module adaptively suppresses the feature inconsistency in different levels and hence obtains the multi-level features with high feature invariance. Then, the SLFR module combines the adaptive features and previous multi-level features at each level to generate the multi-level refined features by skip connection and attention mechanism. The MLFR module adaptively recalibrates the channel-wise and spatial-wise responses by adding the attention operation, which improves the prediction capability of the network. Furthermore, a stage-wise deep supervision (SDS) mechanism and a hybrid loss function are also embedded to enhance the feature learning ability of the network. CT volumes dataset collected in three Chinese medical centers was used to evaluate the segmentation performance of the proposed 3D IFPN model. Experimental results indicate that our method outperforms state-of-the-art segmentation networks in gastric tumor segmentation. Moreover, to explore the generalization for other segmentation tasks, we also extend the proposed network to liver tumor segmentation in CT images of the MICCAI 2017 Liver Tumor Segmentation Challenge.

scholarly journals Liver tumor segmentation in CT volumes using an adversarial densely connected network

2019 ◽  
Vol 20 (S16) ◽  
Author(s):  
Lei Chen ◽  
Hong Song ◽  
Chi Wang ◽  
Yutao Cui ◽  
Jian Yang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Liver Tumor ◽  
Liver Tumors ◽  
Tumor Segmentation ◽  
Malignant Liver Tumor ◽  
Pixel Intensity ◽  
Computed Tomography Images ◽  
Adversarial Training ◽  
Liver Tumor Segmentation ◽  
Segmentation Task

Abstract Background Malignant liver tumor is one of the main causes of human death. In order to help physician better diagnose and make personalized treatment schemes, in clinical practice, it is often necessary to segment and visualize the liver tumor from abdominal computed tomography images. Due to the large number of slices in computed tomography sequence, developing an automatic and reliable segmentation method is very favored by physicians. However, because of the noise existed in the scan sequence and the similar pixel intensity of liver tumors with their surrounding tissues, besides, the size, position and shape of tumors also vary from one patient to another, automatic liver tumor segmentation is still a difficult task. Results We perform the proposed algorithm to the Liver Tumor Segmentation Challenge dataset and evaluate the segmentation results. Experimental results reveal that the proposed method achieved an average Dice score of 68.4% for tumor segmentation by using the designed network, and ASD, MSD, VOE and RVD improved from 27.8 to 21, 147 to 124, 0.52 to 0.46 and 0.69 to 0.73, respectively after performing adversarial training strategy, which proved the effectiveness of the proposed method. Conclusions The testing results show that the proposed method achieves improved performance, which corroborated the adversarial training based strategy can achieve more accurate and robustness results on liver tumor segmentation task.

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