scholarly journals When Everything Revolves Around Internal Carotid Artery: Analysis of Different Management Strategies in Patients With Very Advanced Cancer Involving the Skull Base

2021 ◽  
Vol 11 ◽  
Author(s):  
Ester Orlandi ◽  
Marco Ferrari ◽  
Elvis Lafe ◽  
Lorenzo Preda ◽  
Marco Benazzo ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Head And Neck ◽  
Advanced Cancer ◽  
Management Strategies ◽  
Multimodality Treatment ◽  
Tumor Stage ◽  
Particle Therapy ◽  
Oncologic Outcomes ◽  
Radiological Criteria ◽  
Dismal Prognosis

Internal or common carotid artery encasement (CAE) is observed in almost 2-7% of head and neck cancers (HNC) and designates the tumor with the T4b category. This clinical scenario is associated with a dismal prognosis, owing to the risk for thrombosis and bleeding that usually characterizes such an advanced cancer. Standardized radiological criteria to infer invasion of the carotid artery are lacking. Complete surgical resection in the context of a multimodality treatment is supposed to offer the greatest chances of cure. Surgery can either be carotid-sparing or include carotidectomy. Data on probability of cerebrovascular and non-cerebrovascular complications, risk of carotid blowout, poor oncologic outcomes, and less-than-certain efficacy of diagnostic and interventional preventive procedures against cerebral infarction make it difficult to define surgery as the recommended option among other therapeutic strategies. Non-surgical therapies based on radiation therapy possibly combined with chemotherapy are more frequently employed in HNC with CAE. In this context, carotid blowout is the most feared complication, and its probability increases with tumor stage and cumulative radiation dose received by the vessel. The use of highly conformal radiotherapies such as intensity-modulated particle therapy might substantially improve the manageability of HNC with CAE by possibly reducing the risk of late sequalae. Despite evidence is frail, it appears logical that a case-by-case evaluation through multidisciplinary decision making between head and neck surgeons, radiation oncologists, medical oncologists, diagnostic and interventional radiologists, and vascular surgeons are of paramount value to offer the best therapeutic solution to patients affected by HNC with CAE.

ELECTIVE CAROTID ARTERY LIGATION IN THE TREATMENT OF ADVANCED CANCER OF THE HEAD AND NECK

1971 ◽  
Vol 47 (3) ◽  
pp. 243-245 ◽  
Author(s):  
NORMAN J. JAMES ◽  
ORION H. STUTEVIIXE ◽  
CONRAD TASCHE ◽  
Orion H. Stuteville
Keyword(s):  
Carotid Artery ◽  
Head And Neck ◽  
Advanced Cancer ◽  
Artery Ligation ◽  
Carotid Artery Ligation

Clinical Study of Head and Neck Tumor Patients Who Underwent Carotid Artery Reconstruction

2013 ◽  
Vol 64 (3) ◽  
pp. 199-205
Author(s):  
Akiteru Maeda ◽  
Shunichi Chitose ◽  
Hirohito Umeno ◽  
Buichiro Shin ◽  
Takeharu Ono ◽  
...  
Keyword(s):  
Clinical Study ◽  
Carotid Artery ◽  
Head And Neck ◽  
Head And Neck Tumor ◽  
Tumor Patients ◽  
Neck Tumor ◽  
Carotid Artery Reconstruction ◽  
Artery Reconstruction

Patterns of Care and Survival of Cutaneous Angiosarcoma of the Head and Neck

2020 ◽  
Vol 162 (6) ◽  
pp. 881-887 ◽  
Author(s):  
Clifford Chang ◽  
S. Peter Wu ◽  
Kenneth Hu ◽  
Zujun Li ◽  
David Schreiber ◽  
...  
Keyword(s):  
Head And Neck ◽  
Cox Regression ◽  
Multivariable Analysis ◽  
Multimodality Treatment ◽  
The Elderly ◽  
Hazard Ratio ◽  
Patterns Of Care ◽  
Definitive Treatment ◽  
National Cancer Database ◽  
Curative Intent

Objective To analyze the patterns of care and survival of cutaneous angiosarcomas of the head and neck. Study Design Retrospective cohort study. Setting National Cancer Database. Methods The National Cancer Database was queried to select patients with cutaneous angiosarcoma of the head and neck between 2004 and 2015. For survival analysis, patients were included only if they received definitive treatment and complete data. Prognostic factors were analyzed by univariate and multivariable Cox regression. Results We identified 693 patients diagnosed with head and neck angiosarcomas during the study period. The majority were male (n = 489, 70.6%) and elderly (median, 77 years). A total of 421 patients (60.8%) met the criteria for survival analyses. These patients were treated with surgery and radiation (n = 178, 42.3%), surgery alone (n = 138, 32.8%), triple-modality therapy (n = 48, 11.4%), surgery and chemotherapy (n = 29, 6.9%), and chemoradiation (n = 28, 6.7%). With a median follow-up of 29 months, the 3-year survival was 50.1%. Patients undergoing surgery had better median survival than those who did not (38.1 vs 21.0 months, P = .04). Age, comorbidity, tumor size, and surgical margins were significant factors in univariate analyses. On multivariable analysis, age ≥75 years (hazard ratio, 2.65; 95% CI, 1.80-3.88; P < .001) and positive margins (hazard ratio, 1.91; 95% CI, 1.44-2.51; P < .001) predicted worse overall survival. Conclusion Angiosarcoma of head and neck is a rare malignancy that affects the elderly. Surgical treatment with negative margins is associated with improved survival. Even with curative-intent multimodality treatment, the survival of patients aged ≥75 years is limited.

scholarly journals Long-Term Results of Carotid Artery Stenting in Veterans With Prior Head and Neck Cancer

2017 ◽  
Vol 66 (4) ◽  
pp. e91-e92
Author(s):  
Roy W. Jones ◽  
Adam Tanious ◽  
Paul Armstrong ◽  
Neil Moudgill ◽  
Karl A. Illig ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Carotid Artery ◽  
Head And Neck ◽  
Neck Cancer ◽  
Carotid Artery Stenting ◽  
Long Term Results

Functional outcome after intracerebral haemorrhage – a review of the potential role of antiapoptotic agents

2016 ◽  
Vol 27 (3) ◽  
pp. 317-327 ◽  
Author(s):  
Abubakar Tijjani Salihu ◽  
Sangu Muthuraju ◽  
Zamzuri Idris ◽  
Abdul Rahman Izaini Ghani ◽  
Jafri Malin Abdullah
Keyword(s):  
Functional Outcome ◽  
Intracerebral Haemorrhage ◽  
Neuronal Death ◽  
Potential Role ◽  
Management Strategies ◽  
Experimental Studies ◽  
Neuronal Loss ◽  
Multimodality Treatment ◽  
Mortality And Morbidity

AbstractIntracerebral haemorrhage (ICH) is the second most common form of stroke and is associated with greater mortality and morbidity compared with ischaemic stroke. The current ICH management strategies, which mainly target primary injury mechanisms, have not been shown to improve patient’s functional outcome. Consequently, multimodality treatment approaches that will focus on both primary and secondary pathophysiology have been suggested. During the last decade, a proliferation of experimental studies has demonstrated the role of apoptosis in secondary neuronal loss at the periphery of the clot after ICH. Subsequently, the value of certain antiapoptotic agents in reducing neuronal death and improving functional outcome following ICH was evaluated in animal models. Preliminary evidence from those studies strongly supports the potential role of antiapoptotic agents in reducing neuronal death and improving functional outcome after intracerebral haemorrhage. Expectedly, the ongoing and subsequent clinical trials will substantiate these findings and provide clear information on the most potent and safe antiapoptotic agents, their appropriate dosage, and temporal window of action, thereby making them suitable for the multimodality treatment approach.

Primitive neuroectodermal tumor in the jaw: report of a case

2005 ◽  
Vol 28 (2) ◽  
pp. 167-171
Author(s):  
Toranzo Fernández José Martin ◽  
Salgado-García Nickte-ha ◽  
Santos-Díaz Miguel Ángel
Keyword(s):  
Neural Crest ◽  
Head And Neck ◽  
Primitive Neuroectodermal Tumor ◽  
Malignant Neoplasm ◽  
Stage Iv ◽  
Tumor Stage ◽  
Neuroectodermal Tumor ◽  
Mexican Patient

The neuroectodermal tumor is a malignant neoplasm of round cells originated from the neural crest. The occurrence of this tumor in head and neck is rare.A 5 month old Mexican patient with a primitive neuroectodermic tumor stage IV, in the jaw is reported.

Predictive factors for bleeding carotid artery pseudoaneurysms in patients with previous radiations for head and neck cancers

2021 ◽  
Author(s):  
Zhexi He ◽  
Tin Fong James Zhuang ◽  
Yuen Ting Rebecca Ng ◽  
Horace Cheng ◽  
Macy Tong ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Head And Neck ◽  
Predictive Factors ◽  
Head And Neck Cancers

scholarly journals Variations in the Branching Pattern of External Carotid Artery in South Kerala Population – A Cadaveric Study

2021 ◽  
Vol 8 (22) ◽  
pp. 1780-1785
Author(s):  
Manju Sudhakaran ◽  
Mini Alikunju ◽  
Vandana Latha Raveendran ◽  
Umesan Kannanvilakom Govindapillai
Keyword(s):  
Carotid Artery ◽  
Head And Neck ◽  
Carotid Arteries ◽  
Carotid Bifurcation ◽  
External Carotid Artery ◽  
External Carotid ◽  
Superior Thyroid Artery ◽  
South Indian Population ◽  
Branching Pattern ◽  
South Indian

BACKGROUND External carotid arteries account for a major share of arterial supply of head and neck regions. As variations are frequently observed in the branching pattern of external carotid artery, surgeons, radiologists and anaesthetists often encounter difficulties in various procedures of head and neck. The purpose of this study is to describe the variations in the branching pattern of external carotid artery as observed in South Indian population which definitely reduces its iatrogenic injuries associated with surgical and radiological procedures of head and neck. METHODS This is cross-sectional descriptive study. Bilateral neck dissection was done on twenty-two formalin fixed cadavers to study the branching pattern of external carotid artery during a period of two years in the Department of Anatomy in Government Medical College, Alappuzha. Common carotid, external carotid and internal carotid arteries were dissected. All the branches of external carotid artery were traced and the variations were noted. The distance between carotid bifurcation and point of origin of individual branches of external carotid were measured and statistically analyzed. RESULTS In the present study along with normal branching pattern of external carotid artery, variations like origin of superior thyroid artery from common carotid artery and also from carotid bifurcation were seen. A common linguofacial trunk and direct origin of superior laryngeal artery from external carotid artery were also observed. CONCLUSIONS Prior knowledge of the variations will be helpful to surgeons and anaesthetists while dealing with these vessels during procedures of head and neck regions. KEYWORDS External Carotid Artery, Carotid Bifurcation, Superior Thyroid Artery, Linguofacial Trunk

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