scholarly journals Role of Unilateral Vocal Cord Palsy in Causing Recurrent Tracheobronchial Foreign Bodies

2019 ◽  
Vol 7 ◽  
Author(s):  
Laurence Pincet ◽  
Karma Lambercy ◽  
Kishore Sandu
2021 ◽  
pp. 33-38
Author(s):  
Utkarsh Garg ◽  
Harneet Narula ◽  
Manish Gupta ◽  
Ujjwala Singh ◽  
Shreya Singh

Phonation is beyond doubt one of the highest functions of the human larynx. The vocal cords, also known as vocal cords, as the name suggests are infolding of mucosa aligned horizontally. The phonatory process, or voicing, occurs when air is expelled from the lungs through the glottis, creating a pressure drop across the larynx. When this drop becomes sufciently large, the vocal cords start to oscillate. The motion of the vocal cords during oscillation is mostly lateral, though there is also some superior component as well. However, there is almost no motion along the length of the vocal cords. The oscillation of the vocal cords serves to modulate the pressure and ow of the air through the larynx, and this modulated airow is the main component of the sound. The sound that the larynx produces is a harmonic series. In other words, it consists of a fundamental tone (called the fundamental frequency, the main acoustic cue for the percept pitch) accompanied by harmonic overtones, which are multiples of the (1) fundamental frequency .


2019 ◽  
Vol 7 (2) ◽  
pp. 32-35
Author(s):  
Nagaraj Murthy ◽  
◽  
Dimple Bhatia ◽  
Keyword(s):  

2021 ◽  
pp. 1-9
Author(s):  
Aditi Sinha ◽  
Alexander Geragotellis ◽  
Guntaj Kaur Singh ◽  
Devika Verma ◽  
Daniyal Matin Ansari ◽  
...  

Abstract Background: Vocal cord palsy is one of the recognised complications of complex cardiac surgery in the paediatric population. While there is an abundance of literature highlighting the presence of this complication, there is a scarcity of research focusing on the pathophysiology, presentation, diagnosis, and treatment options available for children affected by vocal cord palsy. Materials and methods: Electronic searches were conducted using the search terms: “Vocal Cord Palsy,” “VCP,” “Vocal Cord Injury,” “Paediatric Heart Surgery,” “Congenital Heart Surgery,” “Pediatric Heart Surgery,” “Vocal Fold Movement Impairment,” “VFMI,” “Vocal Fold Palsy,” “PDA Ligation.” The inclusion criteria were any articles discussing the outcomes of vocal cord palsy following paediatric cardiac surgery. Results: The two main populations affected by vocal cord palsy are children undergoing aortic arch surgery or those undergoing PDA ligation. There is paucity of prospective follow-up studies; it is therefore difficult to reliably assess the current approaches and the long-term implications of management options. Conclusion: Vocal cord palsy can be a devastating complication following cardiac surgery, which if left untreated, could potentially result in debilitation of quality of life and in severe circumstances could even lead to death. Currently, there is not enough high-quality evidence in the literature to aid recognition, diagnosis, and management leaving clinicians to extrapolate evidence from adult studies to make clinical judgements. Future research with a focus on the paediatric perspective is necessary in providing evidence for good standards of care.


Materials ◽  
2021 ◽  
Vol 14 (6) ◽  
pp. 1357
Author(s):  
Andreea-Mariana Negrescu ◽  
Anisoara Cimpean

The critical role of the immune system in host defense against foreign bodies and pathogens has been long recognized. With the introduction of a new field of research called osteoimmunology, the crosstalk between the immune and bone-forming cells has been studied more thoroughly, leading to the conclusion that the two systems are intimately connected through various cytokines, signaling molecules, transcription factors and receptors. The host immune reaction triggered by biomaterial implantation determines the in vivo fate of the implant, either in new bone formation or in fibrous tissue encapsulation. The traditional biomaterial design consisted in fabricating inert biomaterials capable of stimulating osteogenesis; however, inconsistencies between the in vitro and in vivo results were reported. This led to a shift in the development of biomaterials towards implants with osteoimmunomodulatory properties. By endowing the orthopedic biomaterials with favorable osteoimmunomodulatory properties, a desired immune response can be triggered in order to obtain a proper bone regeneration process. In this context, various approaches, such as the modification of chemical/structural characteristics or the incorporation of bioactive molecules, have been employed in order to modulate the crosstalk with the immune cells. The current review provides an overview of recent developments in such applied strategies.


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