scholarly journals Vortioxetine Differentially Modulates MK-801-Induced Changes in Visual Signal Detection Task Performance and Locomotor Activity

2018 ◽  
Vol 9 ◽  
Author(s):  
Todd M. Hillhouse ◽  
Christina R. Merritt ◽  
Douglas A. Smith ◽  
Manuel Cajina ◽  
Connie Sanchez ◽  
...  
2015 ◽  
Vol 76 (4) ◽  
pp. 194-203 ◽  
Author(s):  
Kelen C. Freitas ◽  
Todd M. Hillhouse ◽  
Michael D. Leitl ◽  
Steve S. Negus

Perception ◽  
1998 ◽  
Vol 27 (5) ◽  
pp. 609-625 ◽  
Author(s):  
Scott W Brown

This research was designed to examine the consistency of individual differences in timing. Subjects were tested initially on a temporal-signal-detection task. In a series of trials, subjects judged whether a stimulus figure was displayed for either 12 s or greater than 12 s. Task performance was used to classify the subjects into groups with high or low temporal sensitivity ( d'). Later, the subjects were tested on two classic time-judgment tasks. In a temporal-interference task, subjects reproduced intervals of 8 – 16 s during which they had rehearsed 0, 3, or 7 digits. Absolute error in time judgments increased linearly as a function of task demands. However, subjects with low temporal sensitivity made more error under all conditions compared with those with high sensitivity. In an isochronous-tapping task, subjects produced a series of 2-s and 5-s intervals. The low-temporal-sensitivity group produced more variable and inaccurate responses than the high-sensitivity group. The results demonstrate cross-situational consistency in timing performance across different tasks, time-judgment methods, and stimulus durations.


1989 ◽  
Vol 69 (1) ◽  
pp. 199-210 ◽  
Author(s):  
Steven Mongrain ◽  
Lionel Standing

The effects of alcohol on risk-taking, visual signal detection, and perceptual-motor skills were examined under controlled conditions. Skill in two videogame tasks (driving and racquetball simulations) was unaffected by a massive dose of alcohol, whereas risk-taking in the driving task was increased. Alcohol also impaired performance on the signal-detection task, decreasing both perceptual vigilance and caution ( d' and beta). The dependent measures yielded minor correlations with personality and biographical variables, although men were more skilled and riskier in their behaviour than women. A second experiment employing the signal-detection task indicated that even moderate doses of alcohol can significantly impair visual perception and perceptual decision making. Both studies showed that subjects who receive a massive dose of alcohol (bac .12% or .16%) significantly underestimate the amount consumed, and rate themselves as being much less than totally drunk.


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