scholarly journals Post-mortem Characterisation of a Case With an ACTG1 Variant, Agenesis of the Corpus Callosum and Neuronal Heterotopia

2019 ◽  
Vol 10 ◽  
Author(s):  
Regina Vontell ◽  
Veena G. Supramaniam ◽  
Alice Davidson ◽  
Claire Thornton ◽  
Andreas Marnerides ◽  
...  
Brain ◽  
1999 ◽  
Vol 122 (1) ◽  
pp. 99-110 ◽  
Author(s):  
J. Robin Highley ◽  
Margaret M. Esiri ◽  
Brendan McDonald ◽  
Mario Cortina-Borja ◽  
Brian M. Herron ◽  
...  

1989 ◽  
Vol 47 (3) ◽  
pp. 371-374 ◽  
Author(s):  
Verônica Maia Gouvea ◽  
Myriam Dumas Hahn ◽  
Leila Chimelli

Intracranial lipomas are rare, usually do not have clinical expression and are located mare frequently in the corpus callosum. Other locations include the spinal cord, midbrain tectum, superior vermis, tuber cinereum, infundibulum and more rarely cerebellopontine angle, hypothalamus, superior medullary velum and insula. We report the case of a lipoma of the left inferior colliculus which was a post-mortem finding in a woman who died of breast cancer. Although there are reports of intracranial lipomas in patients with malignant tumors there is no explanation for the co-existence of the two tumors. The present tumor also includes a segment of a nerve which is not uncommon, but a less common finding was the presence of nests of Schwann cells within it, shown by immunohistochemistry.


2014 ◽  
Vol 4 ◽  
pp. 22 ◽  
Author(s):  
Harun Arslan ◽  
Metin Saylık ◽  
Hüseyin Akdeniz

Ectopic neurohypophysis is a pituitary gland abnormality, which can accompany growth hormone deficiency associated with dwarfism. Here we present magnetic resonance imaging (MRI) findings of a rare case of ectopic neurohypophysis, corpus callosum dysgenesis, and periventricular neuronal heterotopia coexisting, with a review of the literature.


Author(s):  
Shirley Siew ◽  
W. C. deMendonca

The deleterious effect of post mortem degeneration results in a progressive loss of ultrastructural detail. This had led to reluctance (if not refusal) to examine autopsy material by means of transmission electron microscopy. Nevertheless, Johannesen has drawn attention to the fact that a sufficient amount of significant features may be preserved in order to enable the establishment of a definitive diagnosis, even on “graveyard” tissue.Routine histopathology of the autopsy organs of a woman of 78 showed the presence of a well circumscribed adenoma in the anterior lobe of the pituitary. The lesion came into close apposition to the pars intermedia. Its architecture was more compact and less vascular than that of the anterior lobe. However, there was some grouping of the cells in relation to blood vessels. The cells tended to be smaller, with a higher nucleocytoplasmic ratio. The cytoplasm showed a paucity of granules. In some of the cells, it was eosinophilic.


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