Comparison of Outcomes Between Anti-Nuss Operation and Modified Anti-Nuss Operation Using a Flexible Plate for Correcting Pectus Carinatum: A Retrospective Study

Introduction: The anti-Nuss procedure has gradually been found to have several shortcomings in clinical practice. Accordingly, our department previously designed and introduced a new steel plate. However, there is limited evidence regarding its safety and efficacy. Thus, we aim to compare the efficacy and safety of the conventional anti-Nuss operation with those of a modified anti-Nuss operation using a flexible plate.Methods: Patients with pectus carinatum who underwent surgery between January 2014 and August 2019 were consecutively enrolled in this single-center, retrospective study. In all, 53 patients underwent the modified procedure using the new steel plate (new procedure group), whereas 43 underwent the conventional anti-Nuss procedure (traditional procedure group). Outcome analysis was performed using SPSS to compare the intraoperative and postoperative short-term outcomes.Results: All patients in the new procedure group had shorter operation duration (75.23 ± 11.90 vs. 82.45 ± 9.30 min, p = 0.008), postoperative hospitalizations (3.42 ± 0.95 vs. 4.64 ± 1.53 days, p = 0.039), and plate removal surgery durations (40.60 ± 3.47 vs. 60.30 ± 9.75 min, p = 0.041) than patients in the traditional procedure group. There were no significant differences in the length of incision, postoperative Haller index, cost, postoperative surgical outcome, and incidence of complications between the two groups.Conclusion: Our data reveal that the main clinical outcomes were similar for after anti-Nuss operation and modified anti-Nuss operation. However, the modified procedure for pectus carinatum had a shorter operation duration, postoperative hospitalization, and plate removal surgery duration.

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Modified Nuss operation using introducer-bar complex for pectus excavatum in adults: a retrospective study

Journal of Cardiothoracic Surgery ◽

10.1186/s13019-021-01624-6 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Lei Wang ◽

Juan Liu ◽

Yao Li ◽

Tienan Feng ◽

Beibei Cao ◽

...

Keyword(s):

Retrospective Study ◽

Blood Loss ◽

Pectus Excavatum ◽

Operation Time ◽

Nuss Procedure ◽

Plate Removal ◽

Traditional Procedure ◽

Group Outcomes ◽

Significant Difference ◽

Clinical Benefits

Abstract Background Shortcoming of traditional Nuss operation on adults is gradually found in the clinical practice. A new kind of introducer-bar complex was introduced. However, there is limited evidence regarding its safety and efficacy. Therefore, a single center, retrospective study was conducted to address this issue. Methods Patients with pectus excavatum who underwent surgery between January 2015 and June 2017 were consecutively enrolled in this study. In all, 52 patients underwent the modified procedure using the introducer-bar complex (new procedure group), whereas 48 underwent the traditional anti-Nuss procedure (traditional procedure group). Outcomes analysis of balanced baseline was performed to compare the intraoperative and postoperative short-term outcomes. Results All patients in the new procedure group had shorter operation duration (51.54 ± 20.32 vs. 79.45 ± 13.88 min, p = 0.017), postoperative hospitalizations (4.77 ± 1.62 vs. 6.86 ± 2.18 days, p = 0.028), plate removal surgery durations (39.30 ± 8.97 vs. 60.30 ± 10.49 min, p < 0.001), and less blood loss during operation (6.25 ± 4.88 vs. 10.90 ± 5.75 ml, p = 0.003) than patients in the traditional procedure group. There was no significant difference in the length of incision, postoperative Haller index, cost, number of steel bars, postoperative surgical outcome and incidence of complications between the two groups. Conclusion Through the main clinical outcome were similar, our results shown that modified procedure may have the shorter operation time, postoperative hospital stay, and operation time for plate removal and less blood loss, which may bring potential clinical benefits to patients.

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Modified Nuss Operation Using Introducer-Bar Complex for Pectus Excavatum in Adults: A Retrospective Study

10.21203/rs.3.rs-114651/v1 ◽

2020 ◽

Author(s):

Lei Wang ◽

Juan Liu ◽

Yao Li ◽

Tienan Feng ◽

Beibei Cao ◽

...

Keyword(s):

Retrospective Study ◽

Blood Loss ◽

Pectus Excavatum ◽

Operation Time ◽

Nuss Procedure ◽

Plate Removal ◽

Traditional Procedure ◽

Group Outcomes ◽

Significant Difference ◽

Clinical Benefits

Abstract BackgroundShortcoming of traditional Nuss operation on adults is gradually found in the clinical practice. A new kind of introducer-bar complex was introduced. However, there is limited evidence regarding its safety and efficacy. Therefore, a single center, retrospective study was conducted to address this issue.MethodsPatients with pectus excavatum who underwent surgery between January 2015 and June 2017 were consecutively enrolled in this study. In all, 52 patients underwent the modified procedure using the introducer-bar complex (new procedure group), whereas 48 underwent the traditional anti-Nuss procedure (traditional procedure group). Outcomes analysis of balanced baseline was performed to compare the intraoperative and postoperative short-term outcomes.ResultsAll patients in the new procedure group had shorter operation duration (51.54 ± 20.32 vs. 79.45 ± 13.88 min, p = 0.017), postoperative hospitalizations (4.77 ± 1.62 vs. 6.86 ± 2.18 days, p = 0.028), plate removal surgery durations (39.30 ± 8.97 vs. 60.30±10.49 min, p < 0.001), and less blood loss during operation (6.25 ± 4.88 vs. 10.90±5.75ml, p = 0.003) than patients in the traditional procedure group. There was no significant difference in the length of incision, postoperative Haller index, cost, number of steel bars, postoperative surgical outcome and incidence of complications between the two groups.ConclusionThrough the main clinical outcome were similar, our data reveals modified procedure has shorter operation time, postoperative hospital stay, operation time for plate removal and less blood loss, which will bring potential clinical benefits to patients.

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Faculty Opinions recommendation of Short-term Safety and Effectiveness of Sugammadex for Surgical Patients With End-Stage Renal Disease: A Two-Centre Retrospective Study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.736906215.793567917 ◽

2019 ◽

Author(s):

Martijn Boon

Keyword(s):

Retrospective Study ◽

Renal Disease ◽

End Stage Renal Disease ◽

Surgical Patients ◽

Short Term ◽

Stage Renal Disease ◽

End Stage

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50 Troponin is independently associated with increased short-term mortality in hospitalised patients with COVID-19 infection: a retrospective study in an inner city london hospital

10.1136/heartjnl-2021-bcs.50 ◽

2021 ◽

Author(s):

Vijay Shyam-Sundar ◽

Dan Stein ◽

Martina Spazzapan ◽

Andrew Sullivan ◽

Cathy Qin ◽

...

Keyword(s):

Retrospective Study ◽

Inner City ◽

Short Term ◽

London Hospital ◽

Hospitalised Patients ◽

Short Term Mortality

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Intracranial pressure variability predicts short-term outcome after intracerebral hemorrhage: A retrospective study

Journal of the Neurological Sciences ◽

10.1016/j.jns.2013.04.001 ◽

2013 ◽

Vol 330 (1-2) ◽

pp. 38-44 ◽

Cited By ~ 17

Author(s):

Ye Tian ◽

Zengguang Wang ◽

Ying Jia ◽

Shengjie Li ◽

Bin Wang ◽

...

Keyword(s):

Retrospective Study ◽

Intracranial Pressure ◽

Intracerebral Hemorrhage ◽

Short Term ◽

Term Outcome ◽

Short Term Outcome

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UP-03.134 Short-Term Outcome, Morbidity and Quality of Life of Artificial Urinary Sphincter: A Retrospective Study

Urology ◽

10.1016/j.urology.2011.07.1223 ◽

2011 ◽

Vol 78 (3) ◽

pp. S387-S388

Author(s):

L. Kluth ◽

R. Dahlem ◽

P. Reiss ◽

B. Schoensee ◽

J. Hansen ◽

...

Keyword(s):

Quality Of Life ◽

Retrospective Study ◽

Artificial Urinary Sphincter ◽

Short Term ◽

Term Outcome ◽

Short Term Outcome ◽

Urinary Sphincter

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Cemented Total Knee Arthroplasty- A Short Term Clinical, Functional Assessment and Outcome Analysis

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2020/31 ◽

2020 ◽

Vol 9 (03) ◽

pp. 138-141

Author(s):

Meenakshi Sundaram Kandasamy ◽

Kandaswamy Ganesh Shankar Kandaswamy ◽

Sathish Kumar Rajaram ◽

Vijayan Gopala Krishna Kurup

Keyword(s):

Total Knee Arthroplasty ◽

Knee Arthroplasty ◽

Functional Assessment ◽

Outcome Analysis ◽

Short Term ◽

Total Knee

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Effects of Hyponatremia Normalization on the Short-Term Mortality and Rehospitalizations in Patients with Recent Acute Decompensated Heart Failure: A Retrospective Study

Journal of Clinical Medicine ◽

10.3390/jcm5100092 ◽

2016 ◽

Vol 5 (10) ◽

pp. 92 ◽

Cited By ~ 4

Author(s):

Renato De Vecchis ◽

Marco Di Maio ◽

Giuseppina Di Biase ◽

Carmelina Ariano

Keyword(s):

Heart Failure ◽

Retrospective Study ◽

Acute Decompensated Heart Failure ◽

Decompensated Heart Failure ◽

Short Term ◽

Short Term Mortality

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Features and prognosis of cytomegalovirus-associated biliary atresia: a retrospective study

10.21203/rs.3.rs-24899/v1 ◽

2020 ◽

Author(s):

Zhe Wang ◽

Xi-Si Guan ◽

Yue Wu ◽

Qiu-Ming He ◽

Le Li ◽

...

Keyword(s):

Retrospective Study ◽

Biliary Atresia ◽

Statistical Significance ◽

Underlying Mechanism ◽

Gamma Glutamyl Transferase ◽

Cmv Infection ◽

Short Term ◽

Term Outcome ◽

Dna Test ◽

Glutamyl Transferase

Abstract Purpose To investigate the relationship between cytomegalovirus (CMV) infection and biliary atresia (BA) onset, development and short-term prognosis after Kasai operation. Methods A retrospective study was conducted. BA Patients with obstructive jaundice and tested for CMV infection were included and grouped by CMV-IgM and CMV-DNA test results, between-group differences of preoperative blood tests and short-term prognosis indicators were investigated for the statistical significance. Results the CMV infection rate was higher in BA patients compared with non-BA jaundiced patients. Higher preoperative gamma-glutamyl transferase (GGT) level and lymphocyte percentage (Lym%) were significantly corelated with the CMV infection in BA patients. CMV(+) BA Patients had similar short-term outcome comparing with CMV(-) patients. IgM(+)DNA(+) group had highest GGT, total bilirubin (TBiL) and direct bilirubin (DBiL) level. IgM(-)DNA(+) group had the lowest GGT and the highest alkaline phosphatase (ALP) level. IgM(+)DNA(-) group had the highest bodyweight and lymphocyte percentage. The IgM (+)DNA (-) group had more patient achieved complete jaundice clearance than other groups. Conclusion CMV infection may associate to BA development and progression. Perioperative antivirus treatments may be necessary for improving outcome. Better elucidation of the underlying mechanism will require further investigation.

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