Aflibercept in Serous Foveal Detachment in Dome-Shaped Macula: Short-Term Results in a Retrospective Study

Introduction: The anti-Nuss procedure has gradually been found to have several shortcomings in clinical practice. Accordingly, our department previously designed and introduced a new steel plate. However, there is limited evidence regarding its safety and efficacy. Thus, we aim to compare the efficacy and safety of the conventional anti-Nuss operation with those of a modified anti-Nuss operation using a flexible plate.Methods: Patients with pectus carinatum who underwent surgery between January 2014 and August 2019 were consecutively enrolled in this single-center, retrospective study. In all, 53 patients underwent the modified procedure using the new steel plate (new procedure group), whereas 43 underwent the conventional anti-Nuss procedure (traditional procedure group). Outcome analysis was performed using SPSS to compare the intraoperative and postoperative short-term outcomes.Results: All patients in the new procedure group had shorter operation duration (75.23 ± 11.90 vs. 82.45 ± 9.30 min, p = 0.008), postoperative hospitalizations (3.42 ± 0.95 vs. 4.64 ± 1.53 days, p = 0.039), and plate removal surgery durations (40.60 ± 3.47 vs. 60.30 ± 9.75 min, p = 0.041) than patients in the traditional procedure group. There were no significant differences in the length of incision, postoperative Haller index, cost, postoperative surgical outcome, and incidence of complications between the two groups.Conclusion: Our data reveal that the main clinical outcomes were similar for after anti-Nuss operation and modified anti-Nuss operation. However, the modified procedure for pectus carinatum had a shorter operation duration, postoperative hospitalization, and plate removal surgery duration.

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Effects of Hyponatremia Normalization on the Short-Term Mortality and Rehospitalizations in Patients with Recent Acute Decompensated Heart Failure: A Retrospective Study

Journal of Clinical Medicine ◽

10.3390/jcm5100092 ◽

2016 ◽

Vol 5 (10) ◽

pp. 92 ◽

Cited By ~ 4

Author(s):

Renato De Vecchis ◽

Marco Di Maio ◽

Giuseppina Di Biase ◽

Carmelina Ariano

Keyword(s):

Heart Failure ◽

Retrospective Study ◽

Acute Decompensated Heart Failure ◽

Decompensated Heart Failure ◽

Short Term ◽

Short Term Mortality

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Features and prognosis of cytomegalovirus-associated biliary atresia: a retrospective study

10.21203/rs.3.rs-24899/v1 ◽

2020 ◽

Author(s):

Zhe Wang ◽

Xi-Si Guan ◽

Yue Wu ◽

Qiu-Ming He ◽

Le Li ◽

...

Keyword(s):

Retrospective Study ◽

Biliary Atresia ◽

Statistical Significance ◽

Underlying Mechanism ◽

Gamma Glutamyl Transferase ◽

Cmv Infection ◽

Short Term ◽

Term Outcome ◽

Dna Test ◽

Glutamyl Transferase

Abstract Purpose To investigate the relationship between cytomegalovirus (CMV) infection and biliary atresia (BA) onset, development and short-term prognosis after Kasai operation. Methods A retrospective study was conducted. BA Patients with obstructive jaundice and tested for CMV infection were included and grouped by CMV-IgM and CMV-DNA test results, between-group differences of preoperative blood tests and short-term prognosis indicators were investigated for the statistical significance. Results the CMV infection rate was higher in BA patients compared with non-BA jaundiced patients. Higher preoperative gamma-glutamyl transferase (GGT) level and lymphocyte percentage (Lym%) were significantly corelated with the CMV infection in BA patients. CMV(+) BA Patients had similar short-term outcome comparing with CMV(-) patients. IgM(+)DNA(+) group had highest GGT, total bilirubin (TBiL) and direct bilirubin (DBiL) level. IgM(-)DNA(+) group had the lowest GGT and the highest alkaline phosphatase (ALP) level. IgM(+)DNA(-) group had the highest bodyweight and lymphocyte percentage. The IgM (+)DNA (-) group had more patient achieved complete jaundice clearance than other groups. Conclusion CMV infection may associate to BA development and progression. Perioperative antivirus treatments may be necessary for improving outcome. Better elucidation of the underlying mechanism will require further investigation.

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Correlation analysis between short-term insulin-like growth factor-I and glucose intolerance status after transsphenoidal adenomectomy in acromegalic patients: a large retrospective study from a single center in China

Archives of Endocrinology and Metabolism ◽

10.20945/2359-3997000000118 ◽

2019 ◽

Author(s):

Yi-Lin Li ◽

Shuo Zhang ◽

Xiao-Peng Guo ◽

Lu Gao ◽

Wei Lian ◽

...

Keyword(s):

Retrospective Study ◽

Growth Factor ◽

Correlation Analysis ◽

Glucose Intolerance ◽

Insulin Like Growth Factor ◽

Single Center ◽

Short Term ◽

Factor I ◽

Transsphenoidal Adenomectomy ◽

Large Retrospective Study

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Use of percutaneous microwave ablation for the treatment of bone tumors: a retrospective study of clinical outcomes in 47 patients

Cancer Imaging ◽

10.1186/s40644-019-0275-8 ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 2

Author(s):

Min-hao Wu ◽

Ling-fei Xiao ◽

Fei-fei Yan ◽

Shi-Liang Chen ◽

Chong Zhang ◽

...

Keyword(s):

Quality Of Life ◽

Retrospective Study ◽

Pain Relief ◽

Microwave Ablation ◽

Bone Tumors ◽

Short Term ◽

Sf 36 ◽

Percutaneous Microwave Ablation

Abstract Objective The present study aimed to evaluate the short-term clinical performance and safety of percutaneous microwave ablation (MWA) techniques for the treatment of bone tumors. Methods This single-institution retrospective study investigated 47 cases of bone tumors treated by MWA from June 2015 to June 2018. The study included 26 patients (55.3%) with benign bone tumors and 21 patients (44.7%) with malignant bone tumors. The tumors were located in the spine or sacrum (15, 31.9%), the upper extremities (6, 12.8%), the lower extremities (17, 36.2%) and the pelvis (9, 19.1%). Outcomes regarding clinical efficacy, including pain relief, quality of life, and intervention-related complications, were evaluated before and after MWA using the visual analog scale (VAS) and the 36-item Short-Form Health Survey (SF-36) scoring system. Results Of the 47 patients included in this study, all of them completed follow-up examinations, with a mean follow-up duration of 4.8 ± 1.6 months (range, 2–9 months). Significantly improved VAS and SF-36 scores were recorded after the initial treatment (P<0.001), suggesting that almost 100% of patients experienced pain relief and an improved quality of life following surgery. No major intervention-related complications (e.g., serious neurovascular injury or infection) occurred during or after the treatment. We recorded only three minor posttreatment complications (6.4%, 3/47), which were related to thermal injury that caused myofasciitis and affected wound healing. Conclusion In our study, the short-term efficacy of MWA was considerably favorable, with a relatively low rate of complications. Our results also showed that MWA was effective for pain relief and improved patients’ quality of life, making it a feasible treatment alternative for bone tumors.

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Factors Predicting Favorable Short-Term Response to Transforaminal Epidural Steroid Injections for Lumbosacral Radiculopathy

Medicina ◽

10.3390/medicina55050162 ◽

2019 ◽

Vol 55 (5) ◽

pp. 162 ◽

Cited By ~ 1

Author(s):

Dong Yoon Park ◽

Seok Kang ◽

Joo Hyun Park

Keyword(s):

Retrospective Study ◽

Rating Scale ◽

Numerical Rating Scale ◽

Multivariate Logistic Regression Analysis ◽

Short Term ◽

Duration Of Symptoms ◽

Lumbosacral Radiculopathy ◽

Epidural Steroid Injections ◽

Epidural Steroid ◽

Term Response

Background and Objectives: The purpose of this retrospective study was to identify predictors of short-term outcomes associated with a lumbosacral transforaminal epidural steroid injection (TFESI). Materials and Methods: The medical records of 218 patients, who were diagnosed with lumbosacral radiculopathy and treated with a TFESI, were reviewed in this retrospective study. A mixture of corticosteroid, lidocaine, and hyaluronidase was injected during TFESI. Patients with >50% pain relief on the numerical rating scale compared with the initial visit constituted the good responder group. Demographic, clinical, MRI, and electrodiagnostic data were collected to assess the predictive factors for short-term outcomes of the TFESI. Results: A multivariate logistic regression analysis demonstrated that a shorter duration of symptoms and a positive sharp wave (PSW)/fibrillation (Fib) observed in electrodiagnostic study (EDx) increased the odds of significant improvement 2–4 weeks after the TFESI. Conclusions: Shorter duration of symptoms and PSW/Fib on EDx were predictors of favorable short-term response to TFESI.

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