scholarly journals Effect of Zinc Source and Exogenous Enzymes Supplementation on Zinc Status in Dogs Fed High Phytate Diets

Animals ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 400 ◽  
Author(s):  
Ana Margarida Pereira ◽  
Margarida Guedes ◽  
Elisabete Matos ◽  
Edgar Pinto ◽  
Agostinho A. Almeida ◽  
...  
Keyword(s):  
Zinc Sulfate ◽  
Lymphocyte Subsets ◽  
Essential Element ◽  
Latin Squares ◽  
Zinc Availability ◽  
Zinc Source ◽  
Supplemental Zinc ◽  
Exogenous Enzymes ◽  
Regulatory Functions ◽  
Phosphorus Storage

Zinc is an essential element, a cofactor of many enzymes, and performs catalytic, structural and regulatory functions. Once in the gastrointestinal tract, zinc can interact with food constituents. Phytic acid, the major phosphorus storage in plants, limits zinc availability from animal feeds due to the formation of insoluble complexes with phytates. This study tested the effect of supplemental zinc source (zinc sulfate and a chelate zinc proteinate) and the addition of exogenous enzymes from a solid-state fermentation product of Aspergillus niger to a high phytate diet. The study was designed according to three Latin Squares 4 × 4 with a 2 × 2 factorial arrangement of treatments, with four periods, four diets, and 12 young adult Beagles. Periods lasted 5 weeks each. Diets were supplemented with 75 mg/kg of zinc sulfate (IZ) or zinc proteinate (OZ), and without or with 200 mg/kg of exogenous enzymes (IZ+, OZ+). Results showed that zinc proteinate increased the bioavailability of phosphorus, yet the zinc biomarkers remained unaffected by the zinc source, with the exception of lymphocyte subsets that benefit from zinc proteinate. The use of exogenous enzymes did not affect zinc availability nor nutrient and energy digestibility.

scholarly journals Effects of Zinc Source and Enzyme Addition on the Fecal Microbiota of Dogs

2021 ◽  
Vol 12 ◽  
Author(s):  
Ana Margarida Pereira ◽  
Margarida R. G. Maia ◽  
Carlo Pinna ◽  
Giacomo Biagi ◽  
Elisabete Matos ◽  
...  
Keyword(s):  
Zinc Sulfate ◽  
Negative Binomial ◽  
Fecal Microbiota ◽  
Latin Squares ◽  
Linear Discriminant ◽  
Zinc Source ◽  
Organic Zinc ◽  
Zinc Bioavailability ◽  
End Products ◽  
Zinc Sources

Supplemental zinc from organic sources has been suggested to be more bioavailable than inorganic ones for dog foods. However, the bioavailability of zinc might be affected by dietary constituents such as phytates. The present study aimed to evaluate the effects of two zinc sources (zinc sulfate and zinc proteinate) and the addition of a multi-enzymatic complex from the solid-state fermentation of Aspergillus niger on end-products of fecal fermentation and fecal microbiota of adult Beagles fed a high-phytate diet. The experimental design consisted of three 4 × 4 Latin Squares with a 2 × 2 factorial arrangement of treatments (n = 12 Beagles), with four periods and four diets: zinc sulfate without (IZ) or with (IZ +) enzyme addition, and zinc proteinate without (OZ) or with (OZ +) enzyme addition. Enzyme addition significantly affected Faith’s phylogenetic diversity index, whereas zinc source did not affect either beta or alpha diversity measures. Linear discriminant analysis effect size detected nine taxa as markers for organic zinc, 18 for inorganic source, and none for enzyme addition. However, with the use of a negative binomial generalized linear model, further effects were observed. Organic zinc was associated with a significantly higher abundance of Firmicutes and lower Proteobacteria and Bacteroidetes, although at a genus level, the response varied. The DNA abundance of Clostridium cluster I, Clostridium cluster XIV, Campylobacter spp., Ruminococcaceae, Turicibacter, and Blautia was significantly higher in dogs fed IZ and IZ + diets. Higher abundance of genus Lactobacillus was observed in dogs fed enzyme-supplemented diets. End-products of fecal fermentation were not affected by zinc source or enzymes. An increase in some taxa of the phyla Actinobacteria and Firmicutes was observed in feces of dogs fed organic zinc with enzyme addition but not with inorganic zinc. This study fills a gap in knowledge regarding the effect of zinc source and enzyme addition on the fecal microbiota of dogs. An association of zinc bioavailability and bacteria abundance is suggested, but the implications for the host (dog) are not clear. Further studies are required to unveil the effects of the interaction between zinc sources and enzyme addition on the fecal microbial community.

scholarly journals COMPARISON OF THERAPEUTIC EFFICACY OF TOPICAL CORTICOSTEROID AND ORAL ZINC SULFATE-TOPICAL CORTICOSTEROID COMBINATION IN THE TREATMENT OF VITILIGO AT KMCH, KATIHAR, BIHAR

2020 ◽  
pp. 43-45
Author(s):  
Nadia Akram ◽  
Seeba Hussain ◽  
Debarshi Jana
Keyword(s):  
Topical Corticosteroid ◽  
Zinc Sulfate ◽  
Combination Group ◽  
Randomized Controlled ◽  
Treatment And Prevention ◽  
Supplemental Zinc ◽  
Significant Difference ◽  
One Year ◽  
Higher Doses

Background : Vitiligo is the most prevalent pigmentary disorder which occurs worldwide, with an incidence rate between 0.1-4 percent. It is anticipated that the discovery of biological pathways of vitiligo pathogenesis with provide novel therapeutic and prophylactic targets for future approaches to the treatment and prevention of vitiligo. The purposes of this study were evaluating the efficacy of supplemental zinc on the treatment of vitiligo. Methods : This randomized clinical trial was conducted for a period of one year. Thiry five patients among 86 participatnts were eligible to entrance to the study. The patients in two equal randomized groups took topical corticosteroid and comination of oral zinc sulfate-topical corticosteroid. Results : The of responses in the corticosteroid group and the zinc sulfat-corticosteroid combination group were 21.43% and 24.7% respectively. Conclusion : Although, the response to corticosteroid plus zinc sulfate was more than corticosteroid, there was no statistically significant difference between them. It appeared that more robust long-term randomized controlled trials on more patients, may be with higher doses of zinc sulfate, are needed to fully establish the efficacy of oral zinc in management of vitiligo.

scholarly journals Supplemental Zinc Sulfate Affects Growth Performance of Finishing Heifers

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
C. L. Van Bibber-Krueger ◽  
J. S. Drouillard
Keyword(s):  
Growth Performance ◽  
Zinc Sulfate ◽  
Supplemental Zinc

scholarly journals Influence of dietary zinc concentration and supplemental zinc source on nutrient digestibility, zinc absorption, and retention in sheep1

2018 ◽  
Vol 96 (12) ◽  
pp. 5336-5344 ◽  
Author(s):  
Katherine R VanValin ◽  
Olivia N Genther-Schroeder ◽  
Remy N Carmichael ◽  
Christopher P Blank ◽  
Erin L Deters ◽  
...  
Keyword(s):  
Zinc Concentration ◽  
Nutrient Digestibility ◽  
Zinc Absorption ◽  
Dietary Zinc ◽  
Zinc Source ◽  
Supplemental Zinc

scholarly journals Effect of supplemental zinc source and corn particle size on 40-day broiler performance

2017 ◽  
Vol 26 (2) ◽  
pp. 209-218 ◽  
Author(s):  
K.L. Foltz ◽  
B.G. Glover ◽  
J.S. Moritz
Keyword(s):  
Particle Size ◽  
Broiler Performance ◽  
Zinc Source ◽  
Supplemental Zinc ◽  
Corn Particle Size

Zinc availability from zinc lipoate and zinc sulfate in growing rats

2002 ◽  
Vol 16 (3) ◽  
pp. 169-174 ◽  
Author(s):  
Achim Walter ◽  
Klaus Krämer ◽  
Erika Most ◽  
Josef Pallauf
Keyword(s):  
Zinc Sulfate ◽  
Zinc Availability ◽  
Growing Rats

scholarly journals Short communication: Effect of supplemental zinc source with and without evaporative cooling on systemic and mammary metabolism of lactating dairy cows during summer

2020 ◽  
Vol 103 (11) ◽  
pp. 10258-10263
Author(s):  
Thiago N. Marins ◽  
Ana P.A. Monteiro ◽  
Xisha Weng ◽  
Jinru Guo ◽  
Ruth M. Orellana Rivas ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Short Communication ◽  
Evaporative Cooling ◽  
Zinc Source ◽  
Supplemental Zinc ◽  
Lactating Dairy Cows ◽  
Communication Effect ◽  
Mammary Metabolism

scholarly journals Supplemental Zinc Sulfate Interacts with Optaflexx in Feedlot Heifers

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
C. L. Van Bibber-Krueger ◽  
R. G. Amachawadi ◽  
H. M. Scott ◽  
J. M. Gonzalez ◽  
J. S. Drouillard
Keyword(s):  
Zinc Sulfate ◽  
Supplemental Zinc

scholarly journals Effects of supplemental zinc sulfate on growth performance, carcass characteristics, and antimicrobial resistance in feedlot heifers1

2018 ◽  
Vol 97 (1) ◽  
pp. 424-436 ◽  
Author(s):  
Cadra L Van Bibber-Krueger ◽  
Chris I Vahl ◽  
Sanjeev K Narayanan ◽  
Raghavendra G Amachawadi ◽  
Ethan A Taylor ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Growth Performance ◽  
Zinc Sulfate ◽  
Carcass Characteristics ◽  
Supplemental Zinc
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