scholarly journals Diffusion-Weighted Imaging of the Macaque Brain Using Diffusion-Prepared Turbo Spin Echo in MRI

2021 ◽  
Vol 11 (24) ◽  
pp. 12077
Author(s):  
Jialu Zhang ◽  
Xiaotong Zhang

Magnetic resonance imaging (MRI) integrates a static magnetic field, a time-varying gradient magnetic field at kHz and a radio-frequency (RF) magnetic field for non-invasive and real-time imaging; meanwhile, diffusion MRI (dMRI) pushes a further and closer dimension to the scale of neural fibers through sensitizing the gradient field to recognize water molecular displacement over distances of 1~20 μm along fibers. Contemporary dMRI approaches face challenges of magnetic field inhomogeneity as well as sequence-associated distortion and signal loss, the common remedies of which are repeated scans and post-reconstruction algorithms. In this study, over an anesthetized macaque with a customized head coil on 3 T MRI, we have proposed and implemented a monopolar diffusion-prepared module for turbo spin echo sequence (DP-TSE) as an alternative to achieve distortion-free, high-resolution diffusion imaging with improved SNR. The results showed high image quality and SNR efficiency as compared with conventional dMRI methods at millimeter level, allowing us to pursue submillimeter-scale dMRI over non-human primates (NHPs) in a relatively short scan time and without repetitions or post-processing, which could merit and advance our understanding of the structure and organizations of the primate’s brain.

2000 ◽  
Vol 144 (2) ◽  
pp. 243-254 ◽  
Author(s):  
Markus H.J Seifert ◽  
Peter M Jakob ◽  
Vladimir Jellus ◽  
Axel Haase ◽  
Claudia Hillenbrand

2020 ◽  
pp. 028418512092456
Author(s):  
Jingjing Liu ◽  
Hang Jin ◽  
Yinyin Chen ◽  
Caixia Fu ◽  
Caizhong Chen ◽  
...  

Background Cardiac magnetic resonance (MR) has become an essential diagnostic imaging modality in cardiovascular disease. However, the insufficient image quality of traditional breath-hold (BH) T2-weighted (T2W) imaging may compromise its diagnostic accuracy. Purpose To assess the efficacy of the BLADE technique to reduce motion artifacts and improve the image quality. Material and Methods Free-breathing TSE-T2W imaging sequence with cartesian and BLADE k-space trajectory were acquired in 20 patients. Thirty patients underwent conventional BH turbo spin-echo (TSE) T2W imaging and free-breathing BLADE T2W (FB BLADE-T2W) imaging. Twenty-one patients who had a signal loss of myocardium in BH short-axis T2W turbo inversion recovery (TSE-T2W-TIR) were scanned using free-breathing BLADE T2W turbo inversion recovery (BLADE TSE-T2W-TIR). The overall image quality, blood nulling, and visualization of the heart were scored on a 5-point Likert scale. The signal loss of myocardium, incomplete fat suppression near the myocardium, and the streaking or ghosting artifacts were noted in T2W-TIR sequences additionally. Results The overall imaging quality, blood nulling, and the visualization of heart structure of FB BLADE-T2W imaging sequence were significantly better than those of FB T2W imaging with Cartesian k-space trajectory and BH TSE-T2W imaging sequence ( P<0.01). The FB BLADE TSE-T2W-TIR reduces the myocardium signal dropout ( P<0.05), incomplete fat suppression near myocardium ( P<0.05), and the streaking and ghosting artifacts ( P<0.05) in comparison with the BH TSE-T2W-TIR. Conclusions FB BLADE T2W imaging provides improved myocardial visibility, less motion sensitivity, and better image quality. It may be applied in patients who have poor breath-holding capability.


1997 ◽  
Vol 38 (5) ◽  
pp. 863-866 ◽  
Author(s):  
M. G. Stiris ◽  
F. G. Lilleås

Purpose: To evaluate MR imaging of the hip in patients with a clinically suspected impacted fracture of the femoral neck in cases where conventional plain films show negative or equivocal findings. Material and Methods: Twenty-seven such patients were prospectively examined by MR imaging with a 1.0 T unit, within 24 hours of admittance to hospital. A coronal T1-weighted turbo spin-echo sequence (n=27>), and a coronal STIR sequence (n=25) or a coronal T2-weighted turbo spin-echo fat saturation sequence (n=2) were used. The evaluations were made by 2 radiologists with experience in musculoskeletal radiology. Results: There were 6 patients with a pertrochanteric fracture, 2 without and 4 with slight displacement. Five patients had an impacted fracture of the femoral neck, and 3 had a fracture of the superior pubic bone. Of 2 patients with advanced arthrosis, I had an impacted femoral neck fracture and the other a nondisplaced intertrochanteric fracture. There was 1 patient who had sustained a nondisplaced acetabular fracture with increased joint fluid and muscle contusions. Three patients had muscle contusions only. Two patients had bone marrow contusions only, while 2 others with advanced cox-arthrosis had increased joint fluid only. Three patients showed normal findings. Our findings led to emergency surgery in 13 cases, and conservative measures directed to the specific MR findings in 14 patients. Conclusion: MR imaging should be the first modality of choice in examining patients with a clinically suspected impacted fracture of the femoral neck where conventional films show negative or equivocal findings.


2017 ◽  
Vol 381 ◽  
pp. 808
Author(s):  
Y. Murakami ◽  
M. Nakajima ◽  
A. Ueda ◽  
H. Uetani ◽  
M. Kitajima ◽  
...  

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