scholarly journals A Retrospective Cohort Study of Myosteatosis and Quality of Life in Head and Neck Cancer Patients

Cancers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 4283
Author(s):  
Amy L. Shaver ◽  
Katia Noyes ◽  
Heather M. Ochs-Balcom ◽  
Gregory Wilding ◽  
Andrew D. Ray ◽  
...  

Head and neck cancer (HNC) treatment-related morbidity can be detrimental to quality of life (QOL). Myosteatosis is associated with poor QOL in multiple cancers. If predictive of poor QOL trajectories, myosteatosis would be a tool for clinicians to determine which patients may require additional support during treatment. The purpose of this study was to determine if pretreatment myosteatosis is associated with a poor QOL trajectory following treatment completion. Methods: In a retrospective cohort design, myosteatosis was determined from pretreatment CT scans. Both physical and global QOL score was assessed through patient interview on follow-up appointment. Demographic, cancer-specific, and social covariates were collected, reported, and considered as potential confounders. Results: The population of 163 patients was mostly male (82.2%) and white (91.4%) with oropharyngeal cancer (55.8%). Males with myosteatosis had a physical QOL score 46.84 points lower at one-year following treatment completion (p = 0.01) than those with normal muscle density (p = 0.01). Males with myosteatosis averaged 57.57 points lower at one-year post-treatment (p = 0.01) in global QOL scores. Conclusions: Over one year following completion of treatment, patients with myosteatosis reported worse physical and global QOL scores than patients with normal muscle density.

Author(s):  
Natalia Muñoz Vigueras ◽  
Vanessa Gabriela Jerviz Guia ◽  
Isabel Castillo Pérez ◽  
Paula Obeso Benitez ◽  
Javier Martín Núñez ◽  
...  

2015 ◽  
Vol 191 (6) ◽  
pp. 501-510 ◽  
Author(s):  
Silke Tribius ◽  
Marieclaire Raguse ◽  
Christian Voigt ◽  
Adrian Münscher ◽  
Alexander Gröbe ◽  
...  

Head & Neck ◽  
2004 ◽  
Vol 26 (12) ◽  
pp. 1045-1052 ◽  
Author(s):  
Wynia Derks ◽  
Rob J. de Leeuw ◽  
Gerrit Jan Hordijk ◽  
Jacques A. Winnubst

2012 ◽  
Vol 48 (15) ◽  
pp. 2391-2408 ◽  
Author(s):  
W.K.W. So ◽  
R.J. Chan ◽  
D.N.S. Chan ◽  
B.G.M. Hughes ◽  
S.Y. Chair ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1167
Author(s):  
Ylva Tiblom Ehrsson ◽  
Per Fransson ◽  
Sandra Einarsson

Patients with cancer deal with problems related to physical, psychological, social, and emotional functions. The aim was to investigate malnutrition defined by the Global Leadership Initiative on Malnutrition (GLIM) criteria in relation to health-related quality of life, anxiety, and depression in patients with head and neck cancer. This was a prospective observational research study with 273 patients followed at the start of treatment, seven weeks, and one year. Data collection included nutritional status and support, and the questionnaires: European Organization for Research and Treatment of Cancer Head and neck cancer module (EORTC QLQ-H&N35) and the Hospital Anxiety and Depression Scale (HADS). Malnutrition was defined using the GLIM criteria. The study showed that patients with malnutrition had significantly greater deterioration in their health-related quality of life at seven weeks. On a group level, health-related quality of life was most severe at this time point and some scores still implied problems at one year. Significantly, more patients reported anxiety at the start of treatment whereas significantly more patients reported depression at seven weeks. Over the trajectory of care, the need for support often varies. Psychosocial support is imperative and at the end of treatment extra focus should be put on nutritional interventions and managing treatment-related symptoms to improve nutritional status and health-related quality of life. In the long-term, head and neck cancer survivors need help to find strategies to cope with the remaining sequel.


Head & Neck ◽  
2019 ◽  
Vol 42 (3) ◽  
pp. 513-521 ◽  
Author(s):  
Robert F. Stephens ◽  
Christopher W. Noel ◽  
Jie (Susie) Su ◽  
Wei Xu ◽  
Murray Krahn ◽  
...  

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