scholarly journals The Clinical Feature and Treatment Outcome of Ocular Melanoma: A 34-Year Experience in a Tertiary Referral Center

Cancers ◽  
2021 ◽  
Vol 13 (23) ◽  
pp. 5926
Author(s):  
Yu-Yun Huang ◽  
Tzu-Yu Hou ◽  
Wei-Kuang Yu ◽  
Chieh-Chih Tsai ◽  
Shu-Ching Kao ◽  
...  

Malignant melanoma can arise from melanocytes in various structures of the eye, orbit, and ocular adnexa. We reviewed the clinical features and long-term results of all subjects with histologically proved melanoma originating from any of the ocular and periocular structures in a tertiary referral center. Overall, 88 patients including 47 men were recruited. The tumor was primarily located in the uvea, followed by the conjunctiva, orbit, eyelid, and lacrimal sac. Patients with uveal melanoma were diagnosed at a relatively younger age (47.0 years), while those with orbital and eyelid melanomas were older at presentation (79.5 years and 78.5 years, respectively). The overall local recurrence rate was 9% at a median follow-up of 41.0 months, among which orbital and eyelid melanomas recurred most commonly. The overall mortality rate was 41% in a median duration of 27.2 months (IQR, 13–58 months) from diagnosis, with the highest for lacrimal sac melanoma, followed by melanoma of the orbit, uveal, conjunctiva, and eyelid. Despite prompt local control, the risk for metastasis and mortality was high. Therefore, efficient modalities for early diagnosis and treatment of ocular melanoma are necessary.

2019 ◽  
Vol 120 (2) ◽  
pp. 92-101
Author(s):  
Julie Navez ◽  
Jean-François Gigot ◽  
Pierre H. Deprez ◽  
Pierre Goffette ◽  
Laurence Annet ◽  
...  

2018 ◽  
Vol 80 (05) ◽  
pp. 500-504
Author(s):  
Kevin J. Choi ◽  
David W. Jang ◽  
Ali R. Zomorodi ◽  
Patrick J. Codd ◽  
Allan Friedman ◽  
...  

Abstract Objective This study describes the safety and efficacy of mometasone furoate eluting stents in the management of petrous apex cholesterol granuloma approached through an endonasal endoscopic route and assesses the restenosis rate. Methods Consecutive patients undergoing endoscopic endonasal marsupialization of a petrous apex cholesterol granuloma at a tertiary referral center who had a mometasone furoate eluting stent placed intraoperatively were reviewed in a retrospective fashion. Postoperative endoscopy was used to determine success of surgery and stenting. Results Five patients were included in the study, three were primary cases and two patients had revision surgeries performed. The steroid eluting stent was placed successfully and safely in all patients with no dural or vascular injuries. The average follow-up duration was 10.6 months. There was no restenosis in three patients and one patient had an immediate restenosis that was debrided in clinic (revision case). This was patent at the 16 months follow-up. One patient also developed stenosis, 4 months after surgery due to sphenoid sinusitis. Conclusion Mometasone furoate eluting stents are safe and effective in the primary management of petrous apex cholesterol granuloma. Further studies are needed to assess their efficacy in revision cases and for long term results.


2012 ◽  
Vol 75 (4) ◽  
pp. AB387
Author(s):  
Marc F. Catalano ◽  
Mahmoud Lajin ◽  
Naser M. Khan ◽  
Nalini M. Guda ◽  
Joseph E. Geenen

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S961
Author(s):  
E. Panettieri ◽  
A.M. De Rose ◽  
F. Ardito ◽  
A. Coppola ◽  
G. Nuzzo ◽  
...  

Author(s):  
Jeroen Tahon ◽  
Pieter-Jan Geselle ◽  
Bert Vandenberk ◽  
Evelyn E. Hill ◽  
Willy E. Peetermans ◽  
...  

2011 ◽  
Vol 36 (6) ◽  
pp. 1419-1431 ◽  
Author(s):  
Olov Norlén ◽  
Peter Stålberg ◽  
Kjell Öberg ◽  
John Eriksson ◽  
Jakob Hedberg ◽  
...  

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S560
Author(s):  
E. Panettieri ◽  
A.M. De Rose ◽  
F. Ardito ◽  
A. Coppola ◽  
G. Nuzzo ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document