scholarly journals The Histopathology of the Appendix in Children at Interval Appendectomy

Children ◽  
2021 ◽  
Vol 8 (9) ◽  
pp. 811
Author(s):  
Federica Pederiva ◽  
Rossana Bussani ◽  
Vennus Shafiei ◽  
Daniela Codrich ◽  
Edoardo Guida ◽  
...  
Keyword(s):  
Conservative Treatment ◽  
Carcinoid Tumor ◽  
Interval Appendectomy ◽  
Appendiceal Abscess ◽  
Cellular Infiltrate ◽  
Adequate Treatment ◽  
Malignant Lesions ◽  
Grade 3 ◽  
Histopathologic Findings ◽  
Subsequent Interval

Whilst most surgeons agree that conservative treatment of appendiceal abscess in children is an adequate treatment, the need for subsequent interval appendectomy is still controversial. We analyzed the histopathology in interval appendectomy in search of signs of inflammation. All patients admitted between 2010 and 2017 with appendiceal abscess and scheduled for interval appendectomy were reviewed. The specimens were evaluated for grade of inflammation, type and distribution of cellular infiltrate, presence of necrosis or hemorrhage and infiltrate in the serosa. Forty-two patients had appendiceal abscess and were treated conservatively. Seven underwent emergent appendectomy. Thirty-three out of 35 patients underwent elective interval appendectomy. Thirty-two specimens were revised. Carcinoid tumor or other malignant lesions were not found. All of them presented some amount of inflammation, grade 1 to 2 in 53%, grade 3 to 4 in 47%. Twenty-five percent of the specimens had signs of necrosis accompanied by hemorrhage and in more than the half (53%) the infiltrate extended to the serosa. Conclusions: Although the appendix was mostly found not macroscopically inflamed intraoperatively, histology confirmed a certain grade of inflammation even months after the conservative treatment. No correlation was found between histopathologic findings and lapse of time between abscess treatment and interval appendectomy.

Epidemiological and Clinical Studies in Cats with Thoracolumbar Vertebral Fracture and Luxation and Its Management

2020 ◽  
Author(s):  
I. Nath ◽  
S. Dhanalakshmi ◽  
M. R. Das ◽  
S. K. Panda ◽  
A. K. Kundu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Surgical Treatment ◽  
Vertebral Fracture ◽  
Conservative Treatment ◽  
Clinical Outcome ◽  
Epidemiological Data ◽  
Neurological Dysfunction ◽  
Grade 3 ◽  
Time Of Presentation ◽  
Thoracolumbar Vertebral Fracture

Background: Thoraco-lumbar spinal trauma frequently results in neurological dysfunction of varying degrees in domestic cats. The consequences may be permanent disability or death depending on severity and segment of spinal cord affected. Assessment of primary damage to spinal cord is important to prevent secondary damage and complications arising from neurological deficit. Since assessment of neurological dysfunction and its treatment in spinal trauma in cats is an evolving field, the present study was undertaken with an objective to record and associate epidemiological data and clinical examination findings at the time of presentation with clinical outcome on 60th post-treatment day in cats with thoracolumbar vertebral fracture and luxation, for a better clinical approach in this condition. Methods: 24 affected cats were assessed epidemiologically and clinically at the time of presentation. All the cats were treated either conservatively or surgically based on extent of neurological dysfunction and severity of injury on radiographic evaluation. Post-treatment observations was then correlated with epidemiological data and clinical findings to assess the clinical outcome. Result: In the present study, sub-adult semi-domicile cats were most affected and major cause was automobile accident. Presence of concomitant injuries (30%) affected recovery. Thoracolumbar spinal cord segment (T3-L3) was most affected (71%). Among 16 cats with unstable vertebral fractures, 5/6 cats recovered after surgical treatment and 2/10 cats recovered after conservative treatment. Survival and recovery was poor when degree vertebral canal displacement was more than 70% (10 cats). All 7 cats with grade 1 or grade 2 and one cat with grade 3 neurological dysfunction recovered after conservative treatment. 5 cats with grade 3 and 2 cats with grade 4 neurological dysfunction recovered after surgical treatment. Selection of surgical treatment provided better recovery in cats with unstable vertebral fractures and greater degree of neurological dysfunction.

scholarly journals Collision Tumors in Ovary: Case Series and Literature Review

2019 ◽  
pp. 1-10
Author(s):  
Borges A ◽  
Loddo A ◽  
Martins A ◽  
Peiretti M ◽  
Fanni D ◽  
...  
Keyword(s):  
Literature Review ◽  
Ovarian Tumor ◽  
Case Series ◽  
Mucinous Cystadenoma ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Adequate Treatment ◽  
Collision Tumors ◽  
Brenner Tumor ◽  
Malignant Lesions

Histologically distinct tumors that coexist in an organ without any histological admixture at their interface are denominated collision tumors. We report 3 cases of colliding mature cystic teratoma with mucinous cystadenoma and a case of mature cystic teratoma colliding with benign Brenner tumor in the ovary. We also provide a literature review based on 35 previously published ovarian collision cases. Ovarian tumors from all classes, benign, borderline and malignant lesions may collide. Both our case series and the literature review indicate that ovarian tumor collisions tend to be clinically and ultrasonographically/radiologically unrecognized. The awareness among surgeons, radiologists and pathologists of this rare phenomenon and histological recognition are crucial in order to offer adequate treatment to patients. There is a need to identify novel and more specific imaging clues pointing towards collision tumors in the ovary.

Clinical Outcomes for Interval Appendectomy in the Treatment of Acute Appendicitis With an Appendiceal Abscess or Mass

2015 ◽  
Vol 110 ◽  
pp. S560
Author(s):  
Hiromitsu Kinoshita ◽  
Masato Kondo ◽  
Shoichi Kitano ◽  
Yukiko Kumata ◽  
Ryosuke Kita ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Clinical Outcomes ◽  
Interval Appendectomy ◽  
Appendiceal Abscess

A Systematic Review of Perforated Appendicitis and Phlegmon: Interval Appendectomy or Wait-and-See?

2016 ◽  
Vol 82 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Ghaleb Darwazeh ◽  
Steven C. Cunningham ◽  
Gopal C. Kowdley
Keyword(s):  
Systematic Review ◽  
Hospital Stay ◽  
Perforated Appendicitis ◽  
Length Of Hospital Stay ◽  
Nonoperative Treatment ◽  
Nonsurgical Treatment ◽  
Morbidity Rate ◽  
Interval Appendectomy ◽  
Appendiceal Abscess ◽  
Nonsurgical Management

Patients with appendiceal abscess or phlegmon have been traditionally managed with antibiotics and radiologically guided drainage of the abscess. Many studies have questioned the need for interval appendectomy. A systematic review of the nonsurgical treatment of patients with an appendiceal abscess or phlegmon was undertaken. The rate of recurrence after nonsurgical management, morbidity and length of hospital stay was measured. PubMed and Cochrane databases were queried to identify 21 studies reporting the morbidity of nonsurgical treatment of appendiceal phlegmon or abscess, and five studies reporting the morbidity of performing interval appendectomy. Repeat nonsurgical management was compared with that of performing interval appendectomy. The studies included a total of 1943 patients, of which 1400 patients were managed nonsurgically and 543 patients underwent interval appendectomy. Nonoperative treatment had a mean recurrence of 12.4 per cent, a morbidity of 13.3 per cent, and the length of hospital stay was 9.6 days. The mean morbidity rate and length of hospital stay for patients who underwent interval appendectomy was 10.4 per cent and 5.0 days, respectively. Interval appendectomy and repeat nonoperative management in case of recurrence are associated with similar morbidity; however, elective interval appendectomy implies additional operative costs to prevent recurrence in one of eight patients.

scholarly journals Helical Tomotherapy for Inoperable Breast Cancer: A New Promising Tool

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Ciprian Chira ◽  
Youlia M. Kirova ◽  
Xavier Liem ◽  
François Campana ◽  
Dominique Peurien ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Helical Tomotherapy ◽  
Locally Advanced Breast Cancer ◽  
Locally Advanced ◽  
Staging System ◽  
Skin Toxicity ◽  
Adequate Treatment ◽  
Promising Tool ◽  
Large Breast ◽  
Grade 3

Background. We investigated the feasibility of helical tomotherapy (HT) for inoperable large breast tumors, after failing to achieve adequate treatment planning with conformal radiation techniques.Material and Methods. Five consecutive patients with locally advanced breast cancer (LABC) were treated by preoperative HT. All patients received up-front chemotherapy before HT. Irradiated volumes included breast and nodal areas (45–50 Gy) in 4 patients. One patient received a simultaneous integrated boost (55 Gy) to gross tumor volume (GTV) without lymph node irradiation. Acute toxicity was assessed with Common Toxicity Criteria for Adverse Events v.4. Patients were evaluated for surgery at the end of treatment.Results. Patients were staged IIB to IIIC (according to the AJCC staging system 2010). HT was associated in 4 patients with concomitant chemotherapy (5-fluorouracil and vinorelbine). Two patients were scored with grade 3 skin toxicity (had not completed HT) and one with grade 3 febrile neutropenia. One patient stopped HT with grade 2 skin toxicity. All patients were able to undergo mastectomy at a median interval of 43 days (31–52) from HT. Pathological partial response was seen in all patients.Conclusions. HT is feasible with acceptable toxicity profiles, potentially increased by chemotherapy. These preliminary results prompt us to consider a phase II study.

scholarly journals Tu1575 Conservative Treatment and Interval Appendectomy for Acute Appendicitis

2014 ◽  
Vol 146 (5) ◽  
pp. S-1079
Author(s):  
Toshiyuki Moriya ◽  
Kenji Mase ◽  
Koichiro Ozawa ◽  
Shigeo Hasegawa ◽  
Masaomi Mizutani ◽  
...  
Keyword(s):  
Conservative Treatment ◽  
Acute Appendicitis ◽  
Interval Appendectomy

scholarly journals SOLITARY THYROID NODULE

2010 ◽  
Vol 17 (04) ◽  
pp. 598-602
Author(s):  
AIMEL MUNIR TARRAR ◽  
MADIHA SAEED WAHLA ◽  
SOHAIL ILYAS ◽  
Obaid Ullah Khan ◽  
Ahmed Waqas ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Case Series ◽  
Military Hospital ◽  
Thyroid Function Tests ◽  
Adequate Treatment ◽  
Benign Pathology ◽  
Case Series Study ◽  
Solitary Thyroid Nodule ◽  
Malignant Lesions ◽  
Male Patients

Objectives: To determine frequency of malignancy in solitary thyroid nodule. Design: Case-series study. Place and Duration of Study: The study was conducted at Department of Surgery, Combined Military Hospital Rawalpindi, from April 2002 till April 2003. Patients and Methods: Sixty patients with clinical solitary thyroid nodule fulfilled the selection criteria and were included in the study. Thyroid function tests, ultrasonography and thyroid scanning was done. Finally FNAC and histopathology were done in all the operated cases and record was evaluated. Results: Out of 60 cases studied, 8 (13.33%) were found to have malignant lesions. The remaining 52 (86.67%) cases had benign pathology. Male patients with solitary thyroid nodule showed a higher incidence of malignancy 17.65% as compared to females 11.63%. Maximum malignant cases (50%) were found between the ages of 31 to 40 years. Papillary carcinoma was the most common malignancy (50%)found in our study. Conclusions: The incidence of malignancy in solitary thyroid nodule is quite high (13.33%). So people should be educated to attend thyroid clinics for early diagnosis and adequate treatment.

scholarly journals NONSURGICAL TREATMENT AND INTERVAL APPENDECTOMY FOR APPENDICEAL ABSCESS

2010 ◽  
Vol 71 (9) ◽  
pp. 2222-2226
Author(s):  
Katsuhiko MURAKAWA ◽  
Misa MASUYAMA ◽  
Takamasa YAMAMOTO ◽  
Kazuyuki YAMAMOTO ◽  
Yoshihiro MURAKAMI ◽  
...  
Keyword(s):  
Nonsurgical Treatment ◽  
Interval Appendectomy ◽  
Appendiceal Abscess

Treatment of spontaneous anterior interosseous nerve palsy

2020 ◽  
Vol 132 (4) ◽  
pp. 1243-1248
Author(s):  
Narihito Kodama ◽  
Kosei Ando ◽  
Yoshinori Takemura ◽  
Shinji Imai
Keyword(s):  
Surgical Treatment ◽  
Conservative Treatment ◽  
Symptom Onset ◽  
Nerve Palsy ◽  
Manual Muscle Test ◽  
Anterior Interosseous Nerve ◽  
The Mean ◽  
Initial Recovery ◽  
Grade 3

OBJECTIVEThe purpose of this study was to clarify the clinical outcomes of spontaneous anterior interosseous nerve palsy (AINP) treated nonsurgically or surgically.METHODSThe authors retrospectively evaluated the clinical course of 27 patients affected with AINP, treated nonsurgically or surgically. Thirteen patients underwent surgical treatment (interfascicular neurolysis), and 14 patients underwent conservative nonsurgical treatment. The mean patient age at the onset of symptoms was 49 years (range 17–77 years). The mean follow-up duration from onset to the latest follow-up examination was 23 months (range 12–38 months).RESULTSIn 12 of 14 patients receiving conservative treatment, signs of recovery from the palsy were obtained within 6 months. These patients showed a recovery of manual muscle test (MMT) grade ≥ 3. In contrast, 2 patients who took more than 12 months from symptom onset to initial recovery showed poor recovery (MMT grade ≤ 2). Surgical treatment was performed in 13 patients because of no sign of recovery from palsy. The mean period from symptom onset to the operation was 8.4 months (range 6–14 months). Ten of 13 patients who underwent surgical treatment within 8 months after symptom onset showed good recovery, with MMT grade ≥ 4. However, 3 patients who underwent surgical treatment more than 12 months after onset showed recovery with MMT grade ≤ 3.CONCLUSIONSConservative treatment for AINP may be continued when patients show signs of recovery within 6 months after symptom onset. In contrast, surgical treatment may be performed within 8 months from the onset of symptoms when the patients show no recovery signs for 6 months.

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