scholarly journals Atomic-Site-Specific Analysis on Out-of-Plane Elasticity of Convexly Curved Graphene and Its Relationship to s p 2 to s p 3 Re-Hybridization

Crystals ◽  
2018 ◽  
Vol 8 (2) ◽  
pp. 102 ◽  
Author(s):  
Makoto Ashino ◽  
Roland Wiesendanger
Keyword(s):  
Plane Elasticity ◽  
Site Specific ◽  
Atomic Site ◽  
Specific Analysis ◽  
Out Of Plane

scholarly journals Molecular Screening and Analysis Reveal Novel Oral Site-Specific Locations for the Cariogenic Pathogen Scardovia wiggsiae

2021 ◽  
Vol 9 (6) ◽  
pp. 73
Author(s):  
Steven McDaniel ◽  
Jaydene McDaniel ◽  
Katherine M. Howard ◽  
Karl Kingsley
Keyword(s):  
Gingival Crevicular Fluid ◽  
Quantitative Polymerase Chain Reaction ◽  
Orthodontic Brackets ◽  
Oral Disease ◽  
Significant Advance ◽  
Clinical Samples ◽  
Site Specific ◽  
Clinical Patient ◽  
Specific Analysis ◽  
Oral Site

Introduction: Scardovia wiggsiae (SW) is a newly identified cariogenic pathogen associated with severe early childhood caries and oral disease. New studies have confirmed the presence of this organism among clinical samples from both pediatric and adult patients. However, the recent discovery of this organism has left researchers with only limited information available regarding the prevalence of this organism—and virtually no information regarding oral site-specific locations. Based upon this lack of information, the overall objective of this study was to perform an oral site-specific analysis of SW prevalence from clinical samples. Methods: Using an approved human subjects protocol, samples (n = 60) from an existing saliva and site-specific biorepository were identified and screened for SW presence using quantitative polymerase chain reaction (qPCR). These data were summarized and subsequently analyzed for correlations with demographic (age, sex, race or ethnicity) or clinical (body mass index or BMI, primary/mixed/permanent dentition, orthodontic brackets) variables. Results: These data revealed that average DNA concentrations from all sample sites (saliva, dorsum of tongue, gingival crevicular fluid (GCF), biofilm of upper buccal molar, and biofilm of lower lingual incisor) ranged between 13.74 and 14.69 μg/μL, with an overall average of 14.30 μg/μL ± 1.12 (standard error or SE). qPCR screening revealed a total of n = 34/60 or 56.7% of patient samples harboring SW. A total of n = 71/170 specific oral sites harbored this organism, with the majority of the SW-positive participant samples harboring SW at more than one oral site, n = 22/34 or 64.7%, including non-traditional sites such as GCF and the dorsum of the tongue. Weak correlations were found between specific SW outcomes in GCF and type of dentition (permanent; R = 0.2444), as well as SW outcomes in saliva with age (R = 0.228) and presence of orthodontic brackets (R = 0.2118). Conclusions: This study may be among the first to provide oral site-specific analysis to reveal the prevalence and location of Scardovia among clinical patient samples. Moreover, these data also provide some of the first evidence to suggest this organism may be present not only in traditional supragingival tooth-associated biofilm sites, but also in non-traditional oral sites including the dorsum of the tongue and the gingival crevice. Based upon these results, these data may represent a significant advance in our understanding of the potential sites and locations that harbor this organism and may help contribute to our understanding of the prevalence, distribution and potential for the development of oral disease among clinic patients.

scholarly journals Quantitative Chemoproteomics for Site-Specific Analysis of Protein Alkylation by 4-Hydroxy-2-Nonenal in Cells

2015 ◽  
Vol 87 (5) ◽  
pp. 2535-2541 ◽  
Author(s):  
Jing Yang ◽  
Keri A. Tallman ◽  
Ned A. Porter ◽  
Daniel C. Liebler
Keyword(s):  
Site Specific ◽  
Specific Analysis ◽  
In Cells

scholarly journals Global site-specific analysis of glycoprotein N-glycan processing

2018 ◽  
Vol 13 (6) ◽  
pp. 1196-1212 ◽  
Author(s):  
Liwei Cao ◽  
Jolene K Diedrich ◽  
Yuanhui Ma ◽  
Nianshuang Wang ◽  
Matthias Pauthner ◽  
...  
Keyword(s):  
Site Specific ◽  
Specific Analysis

Site-Specific Ground Motion Studies for a Deep Soil Site Near Ahmedabad, Gujarat

2018 ◽  
pp. 31-65
Author(s):  
A. Boominathan ◽  
Krishna Kumar ◽  
R. Vijaya
Keyword(s):  
Seismic Hazard ◽  
Hazard Analysis ◽  
Response Analysis ◽  
Ground Response ◽  
Ground Response Analysis ◽  
Site Specific ◽  
Linear Approach ◽  
Specific Analysis ◽  
Soil Site ◽  
A Site

Design ground motions are usually developed by one of two approaches: by performing site-specific analyses or from provisions of building codes. Although contemporary codes consider the site effects to an extent, they provide more conservative estimates. Hence, site-specific analysis, which involves both the seismic hazard analysis and ground response analysis, is a preferred approach to obtain design ground motions. This chapter presents a site-specific analysis for a site near Ahmedabad, Gujarat. The seismic hazard analysis was carried out by DSHA approach. The site is predominantly characterized by deep stiff sandy clay deposits. Extensive shear wave velocity measurement is used for site classification and ground response analysis. The ground response analysis was carried out by using two approaches: the equivalent linear approach using SHAKE2000 and the non-linear approach using FLAC2D. The deep-stiff-soil site is found to amplify the ground motion. The response from nonlinear analysis is found to be considerably higher than those obtained from the equivalent linear approach.

scholarly journals Global and site‐specific analysis of protein glycosylation in complex biological systems with Mass Spectrometry

2019 ◽  
Vol 38 (4-5) ◽  
pp. 356-379 ◽  
Author(s):  
Haopeng Xiao ◽  
Fangxu Sun ◽  
Suttipong Suttapitugsakul ◽  
Ronghu Wu
Keyword(s):  
Mass Spectrometry ◽  
Biological Systems ◽  
Protein Glycosylation ◽  
Site Specific ◽  
Specific Analysis

scholarly journals The neuropeptide genes SST, TAC1, HCRT, NPY, and GAL are powerful epigenetic biomarkers in head and neck cancer: a site-specific analysis

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Kiyoshi Misawa ◽  
Masato Mima ◽  
Atsushi Imai ◽  
Daiki Mochizuki ◽  
Yuki Misawa ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Site Specific ◽  
Epigenetic Biomarkers ◽  
Specific Analysis ◽  
A Site

scholarly journals A Site-Specific Analysis of the Implications of a Changing Ozone Profile and Climate for Stomatal Ozone Fluxes in Europe

2018 ◽  
Vol 230 (1) ◽  
Author(s):  
Felicity Hayes ◽  
Gina Mills ◽  
Rocio Alonso ◽  
Ignacio González-Fernández ◽  
Mhairi Coyle ◽  
...  
Keyword(s):  
Site Specific ◽  
Ozone Profile ◽  
Specific Analysis ◽  
Ozone Fluxes ◽  
A Site
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