scholarly journals Stereotactic Radiotherapy in the Treatment of Paraneoplastic Vasculitis in Oligometastatic Renal Cell Carcinoma

2021 ◽  
Vol 28 (3) ◽  
pp. 1744-1750
Author(s):  
Laura Burgess ◽  
Marissa Keenan ◽  
Alan Liang Zhou ◽  
Kiefer Lypka ◽  
Delvina Hasimja Saraqini ◽  
...  

Approximately 20% of renal cell carcinoma (RCC) is diagnosed because of paraneoplastic manifestations. RCC has been associated with a large variety of paraneoplastic syndromes (PNS), but it is rarely associated with PNS vasculitis. We present a case of a previously healthy male who presented with systemic vasculitis; bitemporal headaches, diplopia, polyarthritis, palpable purpura, tongue lesion, peri-orbital edema, scleritis, chondritis and constitutional symptoms. He was subsequently found to have oligometastatic RCC. Both his primary lesion and site of oligometastasis were treated with stereotactic radiotherapy (SBRT) and resulted in the resolution of his vasculitis, as well as sustained oncologic response. This is the first case to demonstrate that effective sustained treatment for PNS vasculitis due to oligometastatic RCC is possible with SBRT.

2016 ◽  
Vol 46 (2) ◽  
pp. 93
Author(s):  
Nouval Shahab ◽  
Arry Rodjani ◽  
Rainy Umbas

Renal cell carcinoma (RCC) in children isseldom found. The incidence of thistumor in childhood is estimated to be 0.1-0.3% out of all neoplasms and 2-7% out ofall malignant renal tumors. The Third NationalCancer Survey reported an incidence of only four casesof RCC per year compared to 117 per year of Wilms’tumor.The incidence of RCC has not been reported inIndonesia. This is the first case of childhood RCCfound in our institution. To the best of our knowl-edge, this is the first report of childhood RCC in In-donesia.


2020 ◽  
Vol 4 (3) ◽  
pp. 124-127
Author(s):  
Bruno Nogueira Cesar ◽  
Nilo Eduardo Delboni Nunes ◽  
Maria Amelia Aguiar Hazin ◽  
Renato Demarchi Foresto ◽  
Gianna Mastroianni Kirsztajn ◽  
...  

Spontaneous tumor lysis syndrome is a rare emergency in onco-nephrology that results from extensive cancer cell lysis independent of antitumoral therapy. It is common among hematological tumors and can be rarely seen with solid tumors. In medical literature, there is only one case report with spontaneous tumor lysis syndrome in renal cell carcinoma and it was associated with metastases. To the best of our knowledge, this is the first report of spontaneous tumor lysis syndrome in non-metastatic renal cell carcinoma.


2018 ◽  
Vol 36 (6) ◽  
pp. 849-854 ◽  
Author(s):  
M. Hegemann ◽  
N. Kroeger ◽  
A. Stenzl ◽  
J. Bedke

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e16105-e16105 ◽  
Author(s):  
Emmanuel Meyer ◽  
Dinu Stefan ◽  
David Pasquier ◽  
Guillemette Bernadou ◽  
Gilles Calais ◽  
...  

1998 ◽  
Vol 4 (Supplement 5) ◽  
pp. 266???269 ◽  
Author(s):  
Emilio D. Poggio ◽  
Peter J. Mazzone ◽  
Jeffrey Horvath ◽  
Brian F. Mandell

2018 ◽  
Vol 11 ◽  
pp. 117954761877509 ◽  
Author(s):  
Noriyuki Arakawa ◽  
Atsushi Irisawa ◽  
Goro Shibukawa ◽  
Ai Sato ◽  
Yoko Abe ◽  
...  

While some reports are available regarding metachronous gastric metastasis from renal cell carcinoma after treatment, there are few reports of primary lesion detection based on the diagnosis of a gastric metastatic lesion. The patient in this case was an 80-year-old woman who underwent upper gastrointestinal endoscopy after having developed anorexia 2 months earlier. A submucosal tumor with central umbilication was found in the gastric greater curvature. Endoscopic ultrasonography revealed a solid and hypoechoic mass with hypervascularity on color Doppler imaging that proliferated mainly within the submucosal layer. There was partial exposure of the tumor on the superficial layer. Biopsy was performed, as a neuroendocrine tumor was suspected; however, histopathological findings with immunostaining revealed gastric metastasis from clear renal cell carcinoma. Subsequently, contrast enhanced computed tomography showed right renal cell carcinoma and liver metastasis. Thus, molecularly targeted drug treatment was initiated by the Department of Urology. Our findings indicate that a primary lesion can be identified and prognosis can be assumed based on biopsy of the gastric metastatic lesion. Immunostaining of biopsy samples collected endoscopically could help achieve definite diagnosis.


Sign in / Sign up

Export Citation Format

Share Document