scholarly journals Evaluation of Breast Galactography Using Digital Breast Tomosynthesis: A Clinical Exploratory Study

Diagnostics ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 2060
Author(s):  
Juan Tao ◽  
Hao Liao ◽  
Yuan Liu ◽  
Qingsong Peng ◽  
Wenying Zhu ◽  
...  
Keyword(s):  
Image Quality ◽  
Radiation Dose ◽  
Predictive Value ◽  
Dose Range ◽  
Nipple Discharge ◽  
Digital Breast Tomosynthesis ◽  
Lesion Detection ◽  
Breast Tomosynthesis ◽  
Full Field ◽  
Sensitivity Specificity

Objectives: To compare the application value of digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) in breast galactography. Materials and Methods: A total of 128 patients with pathological nipple discharge (PND) were selected to undergo galactography. DBT and FFDM were performed for each patient after injecting the contrast agent; the radiation dose of DBT and FFDM was calculated, and the image quality was evaluated in consensus by two senior breast radiologists. Histopathologic data were found in 49 of the 128 patients. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for both FFDM- and DBT-galactography were calculated using histopathologic results as a reference standard. Data were presented as percentages along with their 95% confidence intervals (CI). Results: The average age of the 128 patients was 46.53 years. The average glandular dose (AGD) of DBT-galactography was slightly higher than that of FFDM-galactography (p < 0.001). DBT-galactography was 30.7% higher than FFDM-galactography in CC view, while DBT-galactography increased by 21.7% compared with FFDM-galactography in ML view. Regarding catheter anatomic distortion, structure detail, and overall image quality groups, DBT scores were higher than FFDM scores, and the differences were significant for all measures (p < 0.05). In 49 patients with pathological nipple discharge, we found that the DBT-galactography had higher sensitivity, specificity, PPV, and NPV (93.3%, 75%, 97.7%, and 50%, respectively) than FFDM-galactography (91.1%, 50%, 95.3%, and 33.3%, respectively). Conclusions: Compared to FFDM-galactography, within the acceptable radiation dose range, DBT-galactography increases the sensitivity and specificity of lesion detection by improving the image quality, providing more confidence for the diagnosis of clinical ductal lesions.

scholarly journals Visualization of Breast Microcalcifications on Digital Breast Tomosynthesis and 2-Dimensional Digital Mammography Using Specimens

2017 ◽  
Vol 11 ◽  
pp. 117822341770338 ◽  
Author(s):  
Jieun Byun ◽  
Jee Eun Lee ◽  
Eun Suk Cha ◽  
Jin Chung ◽  
Jeoung Hyun Kim
Keyword(s):  
Image Quality ◽  
Digital Mammography ◽  
Digital Breast Tomosynthesis ◽  
Kappa Statistic ◽  
Breast Tomosynthesis ◽  
Full Field ◽  
Full Field Digital Mammography ◽  
Better Than

Purpose: The purpose of this study is to compare the visibility of microcalcifications of digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) using breast specimens. Materials And Methods: Thirty-one specimens’ DBT and FFDM were retrospectively reviewed by four readers. Results: The image quality of microcalcifications of DBT was rated as superior or equivalent in 71.0% by reader 1, 67.8% by reader 2, 64.5% by reader 3, and 80.6% by reader 4. The Fleiss kappa statistic for agreement among readers was 0.31. Conclusions: We suggest that image quality of DBT appears to be comparable with or better than FFDM in terms of revealing microcalcifications.

Comparison of Microcalcifications Detection and Characterization in Digital Breast Tomosynthesis (DBT) With Synthesized 2D Mammography (SM) versus DBT with Full-Field Digital Mammography (FFDM)

2021 ◽  
Vol 104 (9) ◽  
pp. 1503-1510
Keyword(s):  
Radiation Dose ◽  
Sensitivity And Specificity ◽  
Digital Mammography ◽  
Digital Breast Tomosynthesis ◽  
Breast Tomosynthesis ◽  
Full Field ◽  
Full Field Digital Mammography

Background: Synthesized 2D mammography (SM) has been invented to help lower the radiation dose by circumventing the need for acquiring full-field digital mammography (FFDM) when digital breast tomosynthesis (DBT) is performed. Prior studies have compared microcalcifications detection and characterization in FFDM with SM or with DBT alone. Only few studies have compared DBT plus SM and DBT plus FFDM. Objective: To determine the performance of DBT with SM versus DBT with FFDM in detection and characterization of microcalcifications. Materials and Methods: Three hundred three paired examinations of 2D plus DBT images in the same session were performed. Fifty-five biopsyproven malignancy, 198 biopsy-proven benign microcalcifications, and 50 randomly selected negative screening studies were retrospectively reviewed by two radiologists. Comparison of sensitivity and specificity between the two modalities were performed. Results: From the 55 malignant microcalcifications, three cases were missed by DBT with FFDM but detected and correctly categorized as malignant by DBT with SM. Only one case of malignant microcalcifications was not detected by DBT with SM, and the present case was also miscategorized as benign by DBT with FFDM. There were no statistically significant differences in both detections (p=0.42), and characterization (p=0.65) of microcalcification between both modalities. In DBT with SM, the sensitivity was higher, and the specificity was lower for both detection and characterization of microcalcification when compared to DBT with FFDM. Conclusion: DBT in combination with SM is comparable to DBT in combination with FFDM for detection and characterization of microcalcifications. Keywords: Synthesized 2D mammography; Full-field digital mammography; Digital breast tomosynthesis; Microcalcifications detection and characterization

scholarly journals Screening Digital Breast Tomosynthesis: Radiation Dose Among Patients With Breast Implants

2021 ◽  
Author(s):  
Nhu Q Vu ◽  
Curran Bice ◽  
John Garrett ◽  
Colin Longhurst ◽  
Daryn Belden ◽  
...  
Keyword(s):  
Radiation Dose ◽  
Cancer Detection ◽  
Digital Breast Tomosynthesis ◽  
Breast Implants ◽  
Recall Rate ◽  
Screening Mammography ◽  
Chi Square ◽  
Breast Tomosynthesis ◽  
Full Field ◽  
Significant Difference

Abstract Objective To compare the mean glandular dose (MGD), cancer detection rate (CDR), and recall rate (RR) among screening examinations of patients with breast implants utilizing various digital breast tomosynthesis (DBT)-based imaging protocols. Methods This IRB-approved retrospective study included 1998 women with breast implants who presented for screening mammography between December 10, 2013 and May 29, 2020. Images were obtained using various protocol combinations of DBT and 2D digital mammography. Data collected included MGD, implant type and position, breast density, BI-RADS final assessment category, CDR, and RR. Statistical analysis utilized type II analysis of variance and the chi-square test. Results The highest MGD was observed in the DBT only protocol, while the 2D only protocol had the lowest (10.29 mGy vs 5.88 mGy, respectively). Statistically significant difference in MGD was observed across protocols (P &lt; 0.0001). The highest per-view MGD was among DBT full-field (FF) views in both craniocaudal and mediolateral oblique projections (P &lt; 0.0001). No significant difference was observed in RR among protocols (P = 0.17). The combined 2D (FF only) + DBT implant-displaced (ID) views protocol detected the highest number of cancers (CDR, 7.2 per 1000), but this was not significantly different across protocols (P = 0.48). Conclusion The combination of 2D FF views and DBT ID views should be considered for women with breast implants in a DBT-based screening practice when aiming to minimize radiation exposure without compromising the sensitivity of cancer detection. Avoidance of DBT FF in this patient population is recommended to minimize radiation dose.

RELATIONSHIP BETWEEN RADIATION DOSE AND IMAGE QUALITY IN DIGITAL BREAST TOMOSYNTHESIS

2016 ◽  
pp. ncw005
Author(s):  
Maram M. Alakhras ◽  
Claudia Mello-Thoms ◽  
Roger Bourne ◽  
Mary Rickard ◽  
Jennifer Diffey ◽  
...  
Keyword(s):  
Image Quality ◽  
Radiation Dose ◽  
Digital Breast Tomosynthesis ◽  
Breast Tomosynthesis

scholarly journals Preliminary Clinical Experience with Digital Breast Tomosynthesis in the Visualization of Breast Microcalcifications

2013 ◽  
Vol 3 ◽  
pp. 65 ◽  
Author(s):  
Stamatia V. Destounis ◽  
Andrea L. Arieno ◽  
Renee C. Morgan
Keyword(s):  
Image Quality ◽  
Digital Mammography ◽  
Digital Breast Tomosynthesis ◽  
Surgical Excision ◽  
Lesion Size ◽  
Breast Tomosynthesis ◽  
Full Field ◽  
Full Field Digital Mammography ◽  
Institutional Review

Objectives: To compare the visualization and image quality of microcalcifications imaged with digital breast tomosynthesis (DBT) versus conventional digital mammography. Materials and Methods: Patients with microcalcifications detected on full field digital mammography (FFDM) recommended for needle core biopsy were enrolled in the study after obtaining patient's consent and institutional review board approval (n = 177 patients, 179 lesions). All had a bilateral combination DBT exam, after undergoing routine digital mammography, prior to biopsy. The study radiologist reviewed the FFDM and DBT images in a non-blinded comparison and assessed the visibility of the microcalcifications with both methods, including image quality and clarity with which the calcifications were seen. Data recorded included patient demographics, lesion size on FFDM, DBT, and surgical excision (when applicable), biopsy, and surgical pathology, if any. Results: Average lesion size on DBT was 1.5 cm; average lesion size on FFDM was 1.4 cm. The image quality of DBT was assessed as equivalent or superior in 92.2% of cases. In 7.8% of the cases, the FFDM image quality was assessed as equivalent or superior. Conclusion: In our review, DBT image quality appears to be comparable to or better than conventional FFDM in terms of demonstrating microcalcifications, as shown in 92.2% of cases.

scholarly journals Comparison of radiation dose between 2D digital stereotactic versus digital breast tomosynthesis-guided breast biopsies

2021 ◽  
Vol 134 ◽  
pp. 109407
Author(s):  
T. Amir ◽  
S.P Zuckerman ◽  
B. Barufaldi ◽  
A.D Maidment ◽  
E.F Conant
Keyword(s):  
Radiation Dose ◽  
Digital Breast Tomosynthesis ◽  
Breast Tomosynthesis
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