scholarly journals Chromoblastomycosis Caused by Phialophora—Proven Cases from Mexico

2021 ◽  
Vol 7 (2) ◽  
pp. 95
Author(s):  
Sarah A. Ahmed ◽  
Alexandro Bonifaz ◽  
Gloria M. González ◽  
Leandro F. Moreno ◽  
Nickolas Menezes da Silva ◽  
...  
Keyword(s):  
Population Genetics ◽  
Clinical Strains ◽  
Phialophora Verrucosa ◽  
Etiologic Agents ◽  
Genetics And Genomics

Chromoblastomycosis is a chronic severely mutilating disease caused by fungi of the order Chaetothyriales. Classically, Phialophora verrucosa has been listed among these etiologic agents. This species is known to occur in the environment and has been found to cause other infections like phaeohyphomycosis, while reported cases of chromoblastomycosis are scant. Phialophora is phylogenetically diverse, and thus retrospective confirmation of etiology is necessary. We studied ten proven cases of chromoblastomycosis from Mexico and further analyzed the population genetics and genomics of the Phialophora species to understand their pathogenicity and predilection. The clinical strains were molecularly identified as Phialophora americana (n = 4), Phialophorachinensis (n = 4), and Phialophora macrospora (n = 2). No genetic distinction between clinical and environmental strains was possible. Further analysis of strains from diverse origins are needed to address eventual differences in virulence and niche predilection between the species.

A Primer of Population Genetics and Genomics

2020 ◽  
Author(s):  
Daniel L. Hartl
Keyword(s):  
Population Genetics ◽  
Complex Traits ◽  
Evolutionary Biology ◽  
Knowledge Retention ◽  
Learning By Doing ◽  
Human Populations ◽  
Gene Drive ◽  
Molecular Population Genetics ◽  
Genetics And Genomics ◽  
And Mathematics

A Primer of Population Genetics and Genomics, 4th edition, has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics. Recent textbooks have tended to focus on such specialized topics as the coalescent, molecular evolution, human population genetics, or genomics. This primer bucks that trend by encouraging a broader familiarity with, and understanding of, population genetics and genomics as a whole. The overview ranges from mating systems through the causes of evolution, molecular population genetics, and the genomics of complex traits. Interwoven are discussions of ancient DNA, gene drive, landscape genetics, identifying risk factors for complex diseases, the genomics of adaptation and speciation, and other active areas of research. The principles are illuminated by numerous examples from a wide variety of animals, plants, microbes, and human populations. The approach also emphasizes learning by doing, which in this case means solving numerical or conceptual problems. The rationale behind this is that the use of concepts in problem-solving lead to deeper understanding and longer knowledge retention. This accessible, introductory textbook is aimed principally at students of various levels and abilities (from senior undergraduate to postgraduate) as well as practising scientists in the fields of population genetics, ecology, evolutionary biology, computational biology, bioinformatics, biostatistics, physics, and mathematics.

scholarly journals Union of phylogeography and landscape genetics

2016 ◽  
Vol 113 (29) ◽  
pp. 8079-8086 ◽  
Author(s):  
Leslie J. Rissler
Keyword(s):  
Population Genetics ◽  
Landscape Genetics ◽  
Mojave Desert ◽  
Spatially Explicit ◽  
Novel Studies ◽  
Biology I ◽  
Genomic Scale ◽  
Genetics And Genomics ◽  
Lineage Divergence ◽  
Scale Data

Phylogeography and landscape genetics have arisen within the past 30 y. Phylogeography is said to be the bridge between population genetics and systematics, and landscape genetics the bridge between landscape ecology and population genetics. Both fields can be considered as simply the amalgamation of classic biogeography with genetics and genomics; however, they differ in the temporal, spatial, and organismal scales addressed and the methodology used. I begin by briefly summarizing the history and purview of each field and suggest that, even though landscape genetics is a younger field (coined in 2003) than phylogeography (coined in 1987), early studies by Dobzhansky on the “microgeographic races” of Linanthus parryae in the Mojave Desert of California and Drosophila pseudoobscura across the western United States presaged the fields by over 40 y. Recent advances in theory, models, and methods have allowed researchers to better synthesize ecological and evolutionary processes in their quest to answer some of the most basic questions in biology. I highlight a few of these novel studies and emphasize three major areas ripe for investigation using spatially explicit genomic-scale data: the biogeography of speciation, lineage divergence and species delimitation, and understanding adaptation through time and space. Examples of areas in need of study are highlighted, and I end by advocating a union of phylogeography and landscape genetics under the more general field: biogeography.

Abstracts of the International Workshop “ONYGENALES 2020: Basic and Clinical Research Advances in Dermatophytes and Dimorphic Fungi”.

2020 ◽  
Vol 72 (2) ◽  
pp. 163-198
Keyword(s):  
Public Health ◽  
Population Genetics ◽  
Health Professionals ◽  
Susceptibility Testing ◽  
International Workshop ◽  
Keratinophilic Fungi ◽  
Testing Session ◽  
Dimorphic Fungi ◽  
Public Health Professionals ◽  
Genetics And Genomics

The ONYGENALES workshop is a bi-annual meeting organised by ISHAM Working Group ONYGENALES (onygenales.org). It brings together researchers, students, clinicians, laboratorians and public health professionals across biomedical disciplines, who are interested in current developments in dermatophyte, dimorphic and keratinophilic fungi research. The abstracts are arranged according to the thematic sessions as they appeared in the programme: Session 1: Antifungal resistance and susceptibility testing, Session 2: Taxonomy of keratinophilic and dimorphic fungi, Session 3: Taxonomy of dermatophytes, Session 4: Population genetics and genomics, Session 5: Emerging and zoonotic pathogens, Session 6: Epidemiology, Session 7: Diagnostics and treatment approaches, Session 8: Virulence factors and pathogenesis.

scholarly journals Conservation Genetics and Genomics

Genes ◽  
2020 ◽  
Vol 11 (3) ◽  
pp. 318
Author(s):  
Michael Russello ◽  
George Amato ◽  
Robert DeSalle ◽  
Michael Knapp
Keyword(s):  
Population Genetics ◽  
Endangered Species ◽  
Molecular Biology ◽  
Conservation Genetics ◽  
Evolutionary Biology ◽  
Anthropogenic Changes ◽  
Genetics And Genomics

For more than thirty years, methods and theories from evolutionary biology, phylogenetics, population genetics and molecular biology have been used by conservation biologists to better understand threats to endangered species due to anthropogenic changes [...]

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