Between the Lab and the Field: Plants and the Affective Atmospheres Of Southern Science

In view of persistent global inequalities in scientific knowledge production with clear centers and peripheries, this paper examines a lingering concern for many scientists in the Global South: why is it, at times, so hard to have scientific insights from the South recognized? This paper addresses this big question from within a long-term field immersion in a Ugandan–Australian scientific collaboration in molecular biology. I show how disciplinary hierarchies of value affect the distribution of labor between Uganda and Australia and thematize the role of place and its affective atmospheres that texture the quotidian scientific work in this project. Unsurprisingly, they tend to devalue Ugandan sites and contributions, and turn Uganda into a rather unlikely site for new insights to emerge. However, in spite of doing devalued and outsourced “menial” labor such as fieldwork, Ugandan biologists’ fieldwork involves affective encounters with their experimental banana plants that thereby become differently thinkable. The paper argues that attending to affective atmospheres that infuse research sites offers clues about scientists’ position in global hierarchies and at the same time can help make room for insights that emanate from unexpected places.

Beyond the Extra Respiration of Phagocytosis: NADPH Oxidase 2 in Adaptive Immunity and Inflammation

Reactive oxygen species (ROS) derived from the phagocyte NADPH oxidase (NOX2) are essential for host defence and immunoregulation. Their levels must be tightly controlled. ROS are required to prevent infection and are used in signalling to regulate several processes that are essential for normal immunity. A lack of ROS then leads to immunodeficiency and autoinflammation. However, excess ROS are also deleterious, damaging tissues by causing oxidative stress. In this review, we focus on two particular aspects of ROS biology: (i) the emerging understanding that NOX2-derived ROS play a pivotal role in the development and maintenance of adaptive immunity and (ii) the effects of excess ROS in systemic disease and how limiting ROS might represent a therapeutic avenue in limiting excess inflammation.

What is Causal Specificity About, and What is it Good for in Philosophy of Biology?

The concept of causal specificity is drawing considerable attention from philosophers of biology. It became the rationale for rejecting (and occasionally, accepting) a thesis of causal parity of developmental factors. This literature assumes that attributing specificity to causal relations is at least in principle a straightforward (if not systematic) task. However, the parity debate in philosophy of biology seems to be stuck at a point where it is not the biological details that will help move forward. In this paper, I take a step back to reexamine the very idea of causal specificity and its intended role in the parity dispute in philosophy of biology. I contend that the idea of causal specificity across variations as currently discussed in the literature is irreducibly twofold in nature: it is about two independent components that are not mutually entailed. I show this to be the source of prior complications with the notion of specificity itself that ultimately affect the purposes for which it is often invoked, notably to settle the parity dispute.

Dialectical Methodology of the Praxis of Biology

Zwart uses Hegel’s dialectical method to develop a dialectical methodology for assessing biology as technoscience during the Anthropocene. In this paper I will evaluate this use of Hegelian dialectics in biology. I will first elaborate the meaning of Hegel’s method of “Dialectics”. This helps me to evaluate Zwart’s dialectical scientific methodology from the perspective of Hegel’s method of “Dialectics” and to evaluate Zwart’s dialectical scientific methodology from the perspective of the praxis of biology. Finally, I will oppose Zwart’s claim that the synthetic cell is an appropriate case study to demonstrate the relevance of dialectics for understanding contemporary biological research.

Incorporating Physics Principles in General Biology to Promote Integrative Learning and Thinking

Students often struggle to identify correlations among various concepts in STEM courses, such as energy, mechanics, and cellular communication. Integrative learning incorporates numerous concepts and subjects to aid understanding and enhance critical thinking. This research describes an integrative learning approach in a General Biology I course where key physics-based concepts that are connected to biological topics were emphasized. In addition, students’ knowledge and their beliefs towards biology in all General Biology I classes were assessed using American Association of Colleges and Universities’ Integrative Learning VALUE Rubric and the Colorado Learning Attitudes about Science Survey (CLASS). It was found that correlations existed between students’ attitudes towards biology and their overall content knowledge. The results of this study support that integrative learning is a powerful approach to aid in the understanding of physical and biological concepts, leading to improved student success.

Incorporating Physics Principles in General Biology to Promote Integrative Learning and Thinking

Students often struggle to identify correlations among various concepts in STEM courses, such as energy, mechanics, and cellular communication. Integrative learning incorporates numerous concepts and subjects to aid understanding and enhance critical thinking. This research describes an integrative learning approach in a General Biology I course where key physics-based concepts that are connected to biological topics were emphasized. In addition, students’ knowledge and their beliefs towards biology in all General Biology I classes were assessed using American Association of Colleges and Universities’ Integrative Learning VALUE Rubric and the Colorado Learning Attitudes about Science Survey (CLASS). It was found that correlations existed between students’ attitudes towards biology and their overall content knowledge. The results of this study support that integrative learning is a powerful approach to aid in the understanding of physical and biological concepts, leading to improved student success.

Queer Sinofuturism

In this article, I consider posthumanist and techno-scientific aesthetics in Lu Yang’s short film Uterus Man (2013), a film in which a male superhero is interrogating the capacities of a body to mutate, affect, and to be affected. Profoundly influenced by Japanese popular cultural forms such as manga and anime, the artist also draws on sources ranging from Buddhism to developments in neuroscience and biology. I will use the work of post-Deleuzian thinkers Luciana Parisi and David Lapoujade to investigate how the different transformations of the body shown in Uterus Man chart the unpredictable capacity for bodies and matter to mutate in contemporary techno-aesthetic landscapes. In its ambiguity, can Uterus Man contribute to the emergence of a queer Sinofuturism? And what kind of future does the perverse superhero of Uterus Man represent?

From Face-to-Face to Online Modality: Implications for Undergraduate Learning While the World is Temporarily Closed in the Age of COVID-19

The second half of the Spring 2020 semester has been an unprecedented time globally due to the ongoing coronavirus disease 2019 (COVID-19). COVID-19 pandemic has forced more than one billion students out of school, has disrupted the world and led all university courses switched to online instruction social distancing actions taken to limit the spread of the virus. The aim of the present study is to evaluate the pandemic related changes for undergraduate students, to assess their perspectives related to their learning, experiences in two courses, and to discuss the far-reaching potential implications for the upcoming summer and fall semesters. An electronic survey was conducted to gather data on the student perceptions and learning characteristics of this transition from face-to-face (F2F) to online at a medium-sized university in the Southeast in the Spring 2020 semester. Nearly 88% of the participants indicated that the COVID-19 pandemic impacted their education, while 19% indicated that they prefer online over F2F learning. Furthermore, the online modality significantly increased attendance in General Biology I. Our study also showed that the usage of live conferencing and digital applications increased due to the pandemic. The current research fills the gap in the existing literature by providing the first study on the effects of the ongoing COVID-19 pandemic on undergraduate learning and experiences in the most unique dual modality of the Spring 2020 semester.

Impact of Nucleic Acid Sequencing on Viroid Biology

The early 1970s marked two breakthroughs in the field of biology: (i) The development of nucleotide sequencing technology; and, (ii) the discovery of the viroids. The first DNA sequences were obtained by two-dimensional chromatography which was later replaced by sequencing using electrophoresis technique. The subsequent development of fluorescence-based sequencing method which made DNA sequencing not only easier, but many orders of magnitude faster. The knowledge of DNA sequences has become an indispensable tool for both basic and applied research. It has shed light biology of viroids, the highly structured, circular, single-stranded non-coding RNA molecules that infect numerous economically important plants. Our understanding of viroid molecular biology and biochemistry has been intimately associated with the evolution of nucleic acid sequencing technologies. With the development of the next-generation sequence method, viroid research exponentially progressed, notably in the areas of the molecular mechanisms of viroids and viroid diseases, viroid pathogenesis, viroid quasi-species, viroid adaptability, and viroid–host interactions, to name a few examples. In this review, the progress in the understanding of viroid biology in conjunction with the improvements in nucleotide sequencing technology is summarized. The future of viroid research with respect to the use of third-generation sequencing technology is also briefly envisaged.

Political normativity and the functional autonomy of politics

This article argues for a new interpretation of the realist claim that politics is autonomous from morality and involves specific political values. First, this article defends an original normative source: functional normativity. Second, it advocates a substantive functional standard: political institutions ought to be assessed by their capacity to select and implement collective decisions. Drawing from the ‘etiological account’ in philosophy of biology, I will argue that functions yield normative standards, which are independent from morality. For example, a ‘good heart’ is one that pumps blood well, and a good army is one that it is effective at exerting military force. I then interpret realism’s naturalistic conception of politics as an etiological function of social groups: namely making binding collective decisions under persistent disagreement. I conclude that political institutions should be evaluated realistically by how well they perform this task. Finally, I assess trade-offs between this functional political normativity and other moral values. I conclude that justice, fairness, freedom and equality remain obviously important concerns, but only once the basic political function is secured.