scholarly journals A Personal and Practical Answer from A Clinical Perspective

2021 ◽  
Vol 1 (2) ◽  
pp. 149-151
Author(s):  
Bernard Canaud

Restoring sodium and fluid homeostasis in hemodialysis (HD) patients is a crucial aim to reduce cardiovascular burden and improve global outcome. This crucial target is achieved at maximum in one quarter of HD patients according to a recent study. Sodium and fluid balance relies on a multitarget approach involving dietary salt restriction, dialysis salt mass removal and eventually residual kidney function. Salt mass removal in hemodialysis relies on ultrafiltration (convective sodium), the dialysate–plasma sodium gradient (diffusive sodium) and total treatment time. Manual dialysate sodium prescription has three major aims: dialysate–plasma sodium gradient; sodium mass removal target; hemodialysis tolerance and patient risks. In the future, automated dialysate sodium adjustment by HD machine will facilitate this aim.

2020 ◽  
Vol 02 ◽  
Author(s):  
Pia Chatterjee Kirk

Background: Vital tooth whitening has become an integral part of esthetic dentistry and remains one of the safest and most economic options today to improve dental esthetics without removing tooth structure. The tooth whitening materials have evolved into three categories: dentist-prescribed/dispensed (in office and patient home-use), and over-thecounter purchased and applied by patients. Objective: This review outlines the latest advances in dentist prescribed vital teeth whitening techniques, effects on tooth structure, soft tissues, and dental restoratives. Areas requiring additional research are also discussed. Methods: Electronic and manual literature search was conducted for key words such as tooth bleaching, and dental bleaching techniques using PubMed/MEDLINE, followed by manual selection of the studies that included whitening procedures in vital teeth. Results: The two main whitening agents are carbamide peroxide (CP) and hydrogen peroxide (HP or H2O2) whose concentration, duration of contact, and total treatment time can alter results. In addition, factors including the type of stain, and age of patient can affect results. Although whitening agents can affect tooth structure, restorative materials, and gingival tissues, the changes are temporary or can be treated using minimally invasive techniques. Conclusion: Areas requiring further research include the actual mechanism of whitening, its effect on tooth structure and restorative materials, and the development of an easy method to quantitate the degree of whitening in the dental office.


2019 ◽  
Vol 7 (1) ◽  
pp. 70-73
Author(s):  
Hemant Kumar Halwa ◽  
Sumit Kumar Yadav ◽  
Kishor Dutta ◽  
Sandeep Kumar Gupta ◽  
Raju Shrestha ◽  
...  

Correction of a severe bimaxillary protrusion with maximum anchorage can be challenging. This case report describes the treatment of a girl with a bimaxillary protrusion. Orthodontic treatment included extraction of her 4 first premolars. The total treatment time was 18 months. Her dental proclination and facial appearance was significantly improved.


Author(s):  
I. Takahashi ◽  
K. Kashiwado ◽  
N. Sumida ◽  
T. Ubagai ◽  
H. Kakizawa ◽  
...  

2020 ◽  
Vol 48 (8) ◽  
pp. 030006052094730
Author(s):  
Ya Huang ◽  
Jing-Guo Nong ◽  
Qiao Xue ◽  
Quan-Zhou Feng ◽  
Cai-Yi Lu

Objective To evaluate the efficacy of the figure-of-eight (FOE) suture technique in the treatment of tunnel bleeding after femoral artery puncture compared with manual compression (MC). Methods This prospective, randomized, controlled study enrolled patients that had received transfemoral coronary artery angiography or percutaneous coronary intervention and then developed tunnel bleeding. They were randomly assigned into two groups: FOE suture group (ES group) and manual compression group (MC group). Total treatment time, performance frequency, performance time, rate of deep vein thrombosis (DVT) and in-hospital time after the procedure were compared. Results A total of 152 patients were enrolled in the study (ES group, n = 63; MC group, n = 89). Compared with the MC group, the total treatment time (mean ± SD: ES 22.3 ± 5.4 h versus MC 26.8 ± 6.8 h), performance frequency (mean ± SD: ES 2.1 ± 0.7 versus MC 2.6 ± 1.1), performance time (mean ± SD: ES 8.9 ± 2.5 min versus MC 12.3 ± 4.1 min), in-hospital time after the procedure (mean ± SD: ES 3.5 ± 1.2 days versus MC 4.8 ± 2.1 days) and DVT rate (ES 0.0% versus MC 6.7%) were significantly lower in the ES group. Conclusion The FOE suture technique effectively treated tunnel bleeding after femoral artery puncture.


2017 ◽  
Vol 5 (1) ◽  
pp. 68
Author(s):  
Dhaval Lekhadia

This case report describes the orthodontic treatment of an 18-year-old male patient who presented with Straight profile; tongue thrust habit, proclined upper incisors, generalised spacing in upper and lower arches, Katz's class II premolar relation unilaterally, class II canine relation unilaterally with increased overjet and overbite. A butterfly system was used in the treatment combined with frictionless biomechanics in the initial stage of treatment followed by continuous arch mechanics in the later part of treatment. A tongued crib was used to stop the tongue thrust habit along with one elastic swallow exercise. Micro-implant anchorage was used unilaterally in the upper arch for retraction of the entire segment and correction of the unilateral class II canine and premolar relationship. To avoid a dished in profile, a non-extraction treatment was executed. Final corrections of distally tipped canines were achieved using conventional Begg’s  uprighting auxiliaries in the vertical slots of butterfly system in the finishing stage. The case was finished using bite settling elastics. Total treatment time was 1 year 2 months. Aesthetic and functional goals were achieved satisfactorily with proper selection of biomechanics.


2010 ◽  
Vol 28 (34) ◽  
pp. 5061-5066 ◽  
Author(s):  
Edgar Ben-Josef ◽  
Jennifer Moughan ◽  
Jaffer A. Ajani ◽  
Marshall Flam ◽  
Leonard Gunderson ◽  
...  

Purpose To determine whether increased duration of radiation therapy (RT) and overall treatment (RX) time has a detrimental effect in anal cancer. Patients and Methods Data from Radiation Therapy Oncology Group (RTOG) 87-04 and RTOG 98-11 trials were combined to form three treatment groups: RT/fluorouracil (FU)/mitomycin (n = 472), RT/FU/cisplatin (n = 320), and RT/FU (n = 145). Cox proportional hazards models were used with the following variables: RT duration, RT intensity, RX duration, treatment group, age, sex, Karnofsky performance score (KPS), T stage, N stage, and RT dose. Results In the univariate analysis, there was a significant association between RX duration and colostomy failure (CF; hazard ratio [HR] = 1.51; 95% CI, 1.07 to 2.14; P = .02), local failure (HR = 1.52; 95% CI, 1.14 to 2.03; P = .005), locoregional failure (HR = 1.51; 95% CI, 1.15 to 1.98; P = .003), and time to failure (HR = 1.40; 95% CI, 1.10 to 1.79; P = .007). The significance of RX duration was maintained after adjusting for treatment group. In multivariate modeling there was a trend toward an association between RX duration and CF (HR = 1.57; 95% CI, 0.98 to 2.50; P = .06) and a statistically significant association with local failure (HR = 1.96; 95% CI, 1.34 to 2.87; P = .0006). Age, sex, KPS, T stage, N stage, and RT dose, but not RT duration, RT intensity, or RX duration, were found to be statistically significant predictors of OS and colostomy-free survival. Conclusion Total treatment time, but not duration of radiation therapy, seems to have a detrimental effect on local failure and colostomy rate in anal cancer. Induction chemotherapy may contribute to local failure by increasing total treatment time.


Brachytherapy ◽  
2010 ◽  
Vol 9 ◽  
pp. S83
Author(s):  
Zoubir Ouhib ◽  
Andreas Kyriacou ◽  
Benjamin S. Suutari

2001 ◽  
Vol 7 (4) ◽  
pp. 339-345 ◽  
Author(s):  
J. Giner ◽  
V. Gimeno ◽  
G. V. Barbosa-Cánovas ◽  
O. Martín

The feasibility of inhibiting polyphenoloxidase from apple and pear by pulsed electric field processing was evaluated. These treatments significantly lowered polyphenoloxidase activity of enzyme extracts from apple ( Golden deliciousvar.) and pear ( Blanquillavar.). Exponential decay pulses were generated by a laboratory scale electric pulse generator and applied in bipolar mode. Pulse duration was 0.02 ms and electric field intensities were up to 24.6 kV/cm. The temperature of samples never exceeded 15 ºC during pulsed electric field processing treatments. Polyphenoloxidase activities were reduced up to 3.15% and 38.0% initial value in apple extract at 24.6 kV/cm and pear extract at 22.3 kV/cm both for 6 ms total treatment time, respectively. Apple and pear polyphenoloxidase exposed to pulsed electric field processing diminishes their activities following first order kinetics. Rate constants ranged from 132 to 440 ms 1 for apple polyphenoloxidase, whereas for pear 1 and changed exponentially with the applied electric field intensity. Residual polyphenoloxidase activity was correlated to energy density by an exponential decay model.


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