scholarly journals Microwave-Assisted Synthesis and Fluorescent Properties of 4-Phenyl-1,8-naphthalimide

Molbank ◽  
10.3390/m1127 ◽  
2020 ◽  
Vol 2020 (2) ◽  
pp. M1127
Author(s):  
Frank Betancourt ◽  
James Helmkay ◽  
Hongbin Yan
Keyword(s):  
Bovine Serum Albumin ◽  
Fluorescence Quenching ◽  
Boronic Acid ◽  
Bovine Serum ◽  
Microwave Assisted Synthesis ◽  
Fluorescent Properties ◽  
Naphthalic Anhydride ◽  
Microwave Assisted ◽  
Phenyl Boronic Acid ◽  
Chloroform Methanol

4-Phenyl-1,8-naphthalimide was synthesized by imidation of commercially available 4-bromo-1,8-naphthalic anhydride, followed by Suzuki coupling with phenyl boronic acid, both under microwave heating. The microwave-assisted reactions were found to be faster and more efficient than reactions carried out by heating in oil-baths. While this compound was quite fluorescent in solvents such as chloroform, methanol and ethanol, it is virtually non-fluorescent in DMSO; however, upon the addition of water to DMSO solutions of this dye, fluorescence was restored, suggesting a tendency for aggregation-induced emission. The fluorescent properties of 4-phenyl-1,8-naphthalimide were found to be influenced by salt concentrations, likely as a result of hydrophobic effects. While this dye does not show binding to DNA, presence of bovine serum albumin leads to effective fluorescence quenching.

Microwave-assisted green synthesis of some nanoconjugated copolymers: characterisation and fluorescence quenching studies with bovine serum albumin

2016 ◽  
Vol 40 (5) ◽  
pp. 4643-4653 ◽  
Author(s):  
Ufana Riaz ◽  
S. M. Ashraf ◽  
Sadaf Aleem ◽  
Vaibhav Budhiraja ◽  
Sapana Jadoun
Keyword(s):  
Bovine Serum Albumin ◽  
Fluorescence Quenching ◽  
Serum Albumin ◽  
Green Synthesis ◽  
Bovine Serum ◽  
Association Constant ◽  
Microwave Assisted

The copolymer POPD-co-PNA quenches BSA fluorescence revealing many of its photophysical characteristics including a higher association constant and its scintillating presence on the latter.

Microwave-assisted synthesis of bovine serum albumin–gold nanoclusters and their fluorescence-quenched sensing of Hg2+ ions

2016 ◽  
Vol 40 (2) ◽  
pp. 1155-1161 ◽  
Author(s):  
Nai-Yue Hsu ◽  
Yang-Wei Lin
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Gold Nanoclusters ◽  
Microwave Assisted Synthesis ◽  
Fluorescence Sensing ◽  
Microwave Assisted

Fluorescence sensing of Hg2+ ions by BSA–Au NCs based on the metallophilic interaction between Hg2+ and Au+ ions.

scholarly journals Microwave Assisted Synthesis of p-Methoxycinnamamides and p-Methoxy-β-nitrostyrenes from Ethyl p-methoxycinnamate and Screening their Anti-inflammatory Activity

2017 ◽  
Vol 12 (8) ◽  
pp. 1934578X1701200
Author(s):  
Ismiarni Komala ◽  
Supandia ◽  
Nurhasnib ◽  
Ofa Suzanti Betha ◽  
Yardi ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Microwave Oven ◽  
Inflammatory Activity ◽  
Microwave Assisted Synthesis ◽  
Spectroscopic Techniques ◽  
Microwave Assisted ◽  
Anti Inflammatory

A new modification reaction of ethyl p-methoxycinnamate (1) to afford a series of p-methoxycinnamamide and p-methoxy-β-nitrostyrene has been developed by using the assistance of the unmodified microwave oven. The synthesized compounds were characterized by using various spectroscopic techniques and furthermore screened for their anti-inflammatory activity by using anti-denaturation of heat bovine serum albumin (BSA) method. The result of bioassay indicated that p-methoxycinnamamide derivatives and p-methoxy-β-nitrostyrenes showed interesting anti-inflammatory activity.

Interaction between felodipine and bovine serum albumin: fluorescence quenching study

Luminescence ◽  
2009 ◽  
pp. n/a-n/a ◽  
Author(s):  
U. S. Mote ◽  
S. L. Bhattar ◽  
S. R. Patil ◽  
G. B. Kolekar
Keyword(s):  
Bovine Serum Albumin ◽  
Fluorescence Quenching ◽  
Serum Albumin ◽  
Bovine Serum

Interactions of different polyphenols with bovine serum albumin using fluorescence quenching and molecular docking

2012 ◽  
Vol 135 (4) ◽  
pp. 2418-2424 ◽  
Author(s):  
Mihaela Skrt ◽  
Evgen Benedik ◽  
Črtomir Podlipnik ◽  
Nataša Poklar Ulrih
Keyword(s):  
Molecular Docking ◽  
Bovine Serum Albumin ◽  
Fluorescence Quenching ◽  
Serum Albumin ◽  
Bovine Serum

scholarly journals In vitro Interactions of Secnidazole and Its Iron (II), Copper (II) Complexes with Bovine Serum Albumin by Fluorescence Quenching Method

2020 ◽  
Vol 23 (1) ◽  
pp. 1-9
Author(s):  
Md Jamal Hossain ◽  
Md Zakir Sultan ◽  
Mohammad A Rashid ◽  
Md Ruhul Kuddus
Keyword(s):  
Bovine Serum Albumin ◽  
Transition Metal ◽  
Fluorescence Quenching ◽  
Serum Albumin ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Bovine Serum ◽  
Spectroscopic Method ◽  
Van Der Waals Interactions

The current study was designed to investigate the interactions of an antimicrobial drug secnidazole and its two transition metal complexes with bovine serum albumin (BSA). The interactions of secnidazole and its both transition metal complexes were confirmed by the extingushing of fluorescence intensity of the protein. The fluorescence quenching of BSA by the drug and its both metal complexes showed a static quenching process and the reactions followed exothermic mechanism. The fluorescence spectroscopic method was utilized to evaluate the thermodynamic parameters like change of enthalpy (ΔH), entropy (ΔS) and Gibb’s free energy (ΔG) which indicated the bindings of the antimicrobial agent and its both metal chelates were hydrogen bonding and van der Waals interactions. The binding constant and the number of binding sites were also measured by double log plot that indicated the drug or its metal complexes bound with BSA at 1:1 ratio. Bangladesh Pharmaceutical Journal 23(1): 1-9, 2020

Sign in / Sign up

Export Citation Format

Share Document