scholarly journals Retrospective Clinicopathological Analysis of 65 Peri-Implant Lesions

Medicina ◽  
2021 ◽  
Vol 57 (10) ◽  
pp. 1069
Author(s):  
Amir Shuster ◽  
Gal Frenkel ◽  
Shlomi Kleinman ◽  
Oren Peleg ◽  
Clariel Ianculovici ◽  
...  
Keyword(s):  
Giant Cell ◽  
Recurrence Rate ◽  
Pyogenic Granuloma ◽  
Common Finding ◽  
Histopathological Analysis ◽  
Giant Cell Granuloma ◽  
Epithelial Hyperplasia ◽  
Clinicopathological Analysis ◽  
Peripheral Giant Cell Granuloma

Background and Objectives: Peri-implantitis is a common finding among patients with dental implants. There is no consensus regarding the treatment of this disease, but in many cases, surgical treatment is common practice. A histopathological analysis is not an integral part of suggested protocols. The present study investigated the clinical and histopathological parameters of lesions mimicking peri-implantitis and correlated them with the outcome and follow-up data. Materials and Methods: The study included 65 consecutive biopsies taken from peri-implantitis patients between 2008–2019. Results: The three common diagnoses were fibro-epithelial hyperplasia 20 (30.7%), pyogenic granuloma 16 (24.6%), and peripheral giant cell granuloma 15 (23%). There were 18 cases of recurrent lesions in the study group (27.7%). The recurrence rate was the highest in peripheral giant cell granuloma (8, 12.3%), versus 6% in pyogenic granuloma and fibro-epithelial hyperplasia. These differences in the recurrence rate were statistically significant (p = 0.014). Conclusions: This study emphasizes the necessity of submitting tissue of peri-implantitis cases for histopathological analysis since the more locally aggressive lesions (peripheral giant cell granuloma and pyogenic granuloma), which comprise nearly half of the cases in this study, do not differ in clinical or radiographic characteristics from other peri-implant lesions.

scholarly journals An analysis of the prevalence of peripheral giant cell granuloma and pyogenic granuloma in relation to a dental implant

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nieves Román-Quesada ◽  
Beatriz González-Navarro ◽  
Keila Izquierdo-Gómez ◽  
Enric Jané-Salas ◽  
Antonio Marí-Roig ◽  
...  
Keyword(s):  
Giant Cell ◽  
Dental Implants ◽  
Recurrence Rate ◽  
Pyogenic Granuloma ◽  
High Recurrence Rate ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Oral Implants ◽  
Time Restrictions ◽  
Peripheral Giant Cell Granuloma

Abstract Background The aim of the present investigation was to evaluate the literature recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants. It’s important to know the characteristics present in these lesions and possible effects on the prognosis of dental implants. Methods An electronic search without time restrictions was done in the databases: PubMed/Medline. With the keywords "Granuloma" OR "Granuloma, Giant Cell" OR "peripheral giant cell" OR "Granuloma, Pyogenic” AND "Dental implants" OR "Oral implants”. Results After applying the inclusion and exclusion criteria, a total of 20 articles were included, which reported 32 lesions (10 pyogenic granulomas, 21 peripheral giant cell granulomas and one peripheral giant cell granuloma combined with peripheral ossifying fibroma, all associated with implants). According to our review, these lesions are more frequent in males and in the posterior region of the mandible. Both excision and curettage of the lesion, compared to only excision, presented similar recurrences (40%). Explantation of the implant was performed in 41% of cases without additional recurrences. The results are not statistically significant when comparing one lesion to the other in terms of explantation (p = 0.97), recurrence (p = 0.57) or bone loss (p = 0.67). Conclusions The main therapeutic approach is tissue excision. The lesions show a high recurrence rate (34.4%), which often requires explantation of the associated implant. This recurrence rate is not affected by curettage after excision.

scholarly journals Reactive Hyperplastic Lesions of the Gingiva: A Retrospective Study of 260 Cases

2012 ◽  
Vol 3 (2) ◽  
pp. 126-130 ◽  
Author(s):  
Sangeetha Ramu ◽  
Charlotte Rodrigues
Keyword(s):  
Retrospective Study ◽  
Giant Cell ◽  
Pyogenic Granuloma ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Multicenter Studies ◽  
Age And Gender ◽  
Peripheral Giant Cell Granuloma ◽  
The Mean ◽  
And Gender

ABSTRACT Objectives The purpose of the study was to analyze the frequency and distribution of gingival lesions in MR Ambedkar Dental College, Bengaluru. Materials and methods The material included the biopsies of all localized reactive hyperplastic lesions (LRHL) of the gingiva stored in the department's database (1995-2011). The lesions were analyzed according to their location and the patient's age and gender. The findings were compared with other published studies on reactive lesions. Results A total of 260 reactive lesion biopsies were accessed. focal fibrous hyperplasia (FFH) was the most common (38.5%), followed by pyogenic granuloma (PG) (34.6%), peripheral ossifying fibroma (POF) (17.7%) and peripheral giant cell granuloma (PGCG) (9.2%). The mean age of the patients was 33 years, with a range varying from 9 to 80 years. The LRHL occurred more commonly in females except focal fibrous hyperplasia, which showed male predilection. PG and POF were more common in the maxilla and FFH as well as PGCG were more common in the mandible. Conclusion This study indicates some differences in age and gender distribution as well as in location between the different lesions. The results of this study differ from those of other studies and the data presented here can be used as a guide for further multicenter studies. How to cite this article Ramu S, Rodrigues C. Reactive Hyperplastic Lesions of the Gingiva: A Retrospective Study of 260 Cases. World J Dent 2012;3(2):126-130.

scholarly journals Clinical Management of a Peri-Implant Giant Cell Granuloma

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
A. Pacifici ◽  
D. Carbone ◽  
R. Marini ◽  
G. L. Sfasciotti ◽  
L. Pacifici
Keyword(s):  
Giant Cell ◽  
Dental Implant ◽  
Correct Diagnosis ◽  
Excisional Biopsy ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma ◽  
Natural Teeth ◽  
Implant Therapy

Purpose. Implant therapy plays an important role in contemporary dentistry with high rates of long-term success. However, in recent years, the incidence of peri-implantitis and implant failures has significantly increased. The peripheral giant cell granuloma (PGCG) rarely occurs in peri-implant tissues and it is clinically comparable to the lesions associated with natural teeth. Therefore, the study of possible diseases associated with dental implants plays an important role in order to be able to diagnose and treat these conditions.Materials and Methods. This report described a 60-year-old Caucasian male who presented a reddish-purple pedunculated mass, of about 2 cm in diameter, associated with a dental implant and the adjacent natural tooth.Results. An excisional biopsy was performed and the dental implant was not removed. Histological examination provided the diagnosis of PGCG. After 19-month follow-up, there were no signs of recurrence of peri-implantitis around the implant.Conclusion. The correct diagnosis and appropriate surgical treatment of peri-implant giant cell granuloma are very important for a proper management of the lesion in order to preserve the implant prosthetic rehabilitation and prevent recurrences.

Peripheral Giant Cell Granuloma Associated With Dental Implants: Clinical Case and Literature Review

2012 ◽  
Vol 38 (S1) ◽  
pp. 527-532 ◽  
Author(s):  
Maria A. Peñarrocha-Diago ◽  
Juan Cervera-Ballester ◽  
Laura Maestre-Ferrín ◽  
David Peñarrocha-Oltra
Keyword(s):  
Giant Cell ◽  
Dental Implants ◽  
Histological Study ◽  
Complete Resection ◽  
Fourth Quadrant ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma ◽  
Soft Tissue Complication ◽  
Fixed Prosthesis

Peripheral giant cell granuloma (PGCG) associated to dental implants is a very infrequent peri-implant soft-tissue complication, with only 11 cases recorded in the literature to date. The present study describes a 54-year-old woman presenting a swelling of the alveolar margin in the fourth quadrant in relation to a fixed prosthesis cemented over implants. Treatment consisted of complete resection of the lesion with implantoplasty of the exposed implant threads. The diagnosis of PGCG was confirmed by histological study, and no relapse has been recorded after 12 months of follow-up.

scholarly journals Inflammatory (Reactive) Hyperplastic conditions in puberty

2020 ◽  
Vol 6 (2) ◽  
pp. 109-111
Author(s):  
Vinita Thapa ◽  
Preeti Dhawan ◽  
Nitin Khanduri ◽  
Brijesh Gupta
Keyword(s):  
Giant Cell ◽  
Pyogenic Granuloma ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Peripheral Ossifying Fibroma ◽  
Peripheral Giant Cell Granuloma ◽  
Localize Growth

The gingiva is often the site of localize growth that are considered to be reactive rather than neoplastic in nature.Many of these lesions are difficult to be identified clinically and can only be identified by histological examination.Many types of localized reactive lesions occurring on the gingiva includes focal fibrous hyperplasia, pyogenic granuloma, peripheral giant cell granuloma and peripheral ossifying fibroma . Clinical reports of  12 and 13 year old girls with Pyogenic Granuloma and Peripheral ossifying fibroma are presented.

scholarly journals A Conservative Surgical Approach Towards Central Giant Cell Granuloma: A Case Report

2018 ◽  
Vol 30 (3) ◽  
pp. 1-4
Author(s):  
Ahmed Al-Qattan
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Surgical Approach ◽  
Pyogenic Granuloma ◽  
Histopathological Analysis ◽  
Giant Cell Granuloma ◽  
Case Presentation ◽  
Central Giant Cell Granuloma ◽  
History Of ◽  
Bony Lesion

Central giant cell granuloma (CGCG) is an infrequent benign bony lesion of unpredictably aggressive behavior. The precise lesion character is debatable and remains inconclusive. However, three main theories were proposed: a sensitive lesion, a kind of neoplasm, or a developmental anomaly. This is a case presentation of a 16-year-old boy with a dental history of extraction of the lower right first molar, presented to hospital with two months history of swelling in the aforementioned area after the procedure. First biopsy of the swelling was performed outside the Kingdom of Bahrain. As per histopathological findings, the swelling was described as pyogenic granuloma. Second biopsy with necessary workup was conducted in the Kingdom of Bahrain and was confirmed as central giant cell granuloma through histopathological analysis; it was removed surgically.

scholarly journals Peripheral giant cell granuloma associated with a dental implant

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Rafaela Carriço Porto Baesso ◽  
Maria Carolina de Lima Jacy Monteiro Barki ◽  
Rebeca de Souza Azevedo ◽  
Karla Bianca Fernandes da Costa Fontes ◽  
Débora Lima Pereira ◽  
...  
Keyword(s):  
Giant Cell ◽  
Histological Examination ◽  
Dental Implant ◽  
Excisional Biopsy ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Case Presentation ◽  
Peripheral Giant Cell Granuloma ◽  
Left Mandible

Abstract Background Peripheral giant cell granuloma (PGCG) is an uncommon pathology that affects gingival or alveolar mucosa. Although PGCG can be associated with dental implants, little is known about this lesion and implant osseointegration as well as its etiopathogenesis and the treatments available. This study sought to report a rare case of PGCG associated with dental implant, emphasizing its clinical and histopathological aspects. Case presentation A 53-year-old man had an exophytic, reddish lesion, around a crown attached to a dental implant located in the left mandible. Radiographically, there was bone loss around the implant. After excisional biopsy, histological examination revealed a submucosal proliferation of multinucleated giant cells rendering the diagnosis of peripheral giant cell granuloma. Patient has been under follow-up for 6 months with no recurrence. Conclusions Peri-implant lesions must be completely removed to prevent recurrence of PGCG and implant failure, even in cases suspected to be reactive. Besides, histological examination must be performed on all peri-implant reactions to achieve the appropriate diagnosis and, consequently, the best treatment and follow up.

scholarly journals Pyogenic Granuloma/Peripheral Giant-Cell Granuloma Associated with Implants

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Enric Jané-Salas ◽  
Rui Albuquerque ◽  
Aura Font-Muñoz ◽  
Beatríz González-Navarro ◽  
Albert Estrugo Devesa ◽  
...  
Keyword(s):  
Giant Cell ◽  
Successful Treatment ◽  
Case Reports ◽  
Pyogenic Granuloma ◽  
Relevant Information ◽  
Cochrane Library ◽  
Giant Cell Granuloma ◽  
National Library ◽  
Level Of Evidence ◽  
Peripheral Giant Cell Granuloma

Introduction. Pyogenic granuloma (PG) and peripheral giant-cell granuloma (PGCG) are two of the most common inflammatory lesions associated with implants; however, there is no established pathway for treatment of these conditions. This paper aims to illustrate the successful treatment of PG and PGCG and also report a systematic review of the literature regarding the various treatments proposed.Methods. To collect relevant information about previous treatments for PG and PGCG involving implants we carried out electronic searches of publications with the key words “granuloma”, “oral”, and “implants” from the last 15 years on the databases Pubmed, National Library of Medicine’s Medline, Scielo, Scopus, and Cochrane Library.Results. From the electronic search 16 case reports were found showing excision and curettage as the main successful treatment. As no clinical trials or observational studies were identified the authors agreed to present results from a review perspective.Conclusion. This is the largest analysis of PG and PGCG associated with implants published to date. Our review would suggest that PGCG associated with implants appears to have a more aggressive nature; however the level of evidence is very limited. Further cohort studies with representative sample sizes and standard outcome measures are necessary for better understanding of these conditions.

scholarly journals A rare case of peripheral giant cell granuloma

2021 ◽  
Vol 7 (2) ◽  
pp. 138-141
Author(s):  
Gursimrat Kaur Brar ◽  
S P S Sodhi ◽  
Mehak Malhotra ◽  
Poshali Goyal
Keyword(s):  
Giant Cell ◽  
Male Patient ◽  
Rare Case ◽  
Growth Potential ◽  
Biological Behavior ◽  
Giant Cell Granuloma ◽  
Giant Cell Lesion ◽  
Periodontal Membrane ◽  
Peripheral Giant Cell Granuloma

Peripheral Giant Cell Granuloma or the so called “Giant Cell Epulis” is the most common oral giant cell lesion. It is described as non-neoplastic, hyperplastic lesion occurring exclusively on gingival/alveolar crest that appears as a overgrowth of tissues, following trauma or irritation arising from periosteum or periodontal membrane. It can be sessile or pedunculated with size usually less than 2cm. Although being uncommon, this lesion carries a lot of uncertainity in terms of its etiology, growth potential, biological behavior (recurrence), histogenesis of its cells and its treatment. We hereby report a case of a 49-year old male patient, with peripheral giant cell granuloma in mandibular posterior region, who was successfully treated and is on regular follow up since 6 months.

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