scholarly journals Peripheral giant cell granuloma associated with a dental implant

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Rafaela Carriço Porto Baesso ◽  
Maria Carolina de Lima Jacy Monteiro Barki ◽  
Rebeca de Souza Azevedo ◽  
Karla Bianca Fernandes da Costa Fontes ◽  
Débora Lima Pereira ◽  
...  
Keyword(s):  
Giant Cell ◽  
Histological Examination ◽  
Dental Implant ◽  
Excisional Biopsy ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Case Presentation ◽  
Peripheral Giant Cell Granuloma ◽  
Left Mandible

Abstract Background Peripheral giant cell granuloma (PGCG) is an uncommon pathology that affects gingival or alveolar mucosa. Although PGCG can be associated with dental implants, little is known about this lesion and implant osseointegration as well as its etiopathogenesis and the treatments available. This study sought to report a rare case of PGCG associated with dental implant, emphasizing its clinical and histopathological aspects. Case presentation A 53-year-old man had an exophytic, reddish lesion, around a crown attached to a dental implant located in the left mandible. Radiographically, there was bone loss around the implant. After excisional biopsy, histological examination revealed a submucosal proliferation of multinucleated giant cells rendering the diagnosis of peripheral giant cell granuloma. Patient has been under follow-up for 6 months with no recurrence. Conclusions Peri-implant lesions must be completely removed to prevent recurrence of PGCG and implant failure, even in cases suspected to be reactive. Besides, histological examination must be performed on all peri-implant reactions to achieve the appropriate diagnosis and, consequently, the best treatment and follow up.

scholarly journals Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Amy Louise Brown ◽  
Paulo Camargo de Moraes ◽  
Marcelo Sperandio ◽  
Andresa Borges Soares ◽  
Vera Cavalcanti Araújo ◽  
...  
Keyword(s):  
Giant Cell ◽  
Dental Implant ◽  
Excisional Biopsy ◽  
Giant Cells ◽  
Infectious Agents ◽  
Giant Cell Granuloma ◽  
Review Of The Literature ◽  
Peripheral Giant Cell Granuloma ◽  
Foreign Body Reactions

The peripheral giant cell granuloma (PGCG) is a nonneoplastic lesion commonly caused by local irritation. This report describes a 46-year-old Caucasian male who presented with a PGCG associated with a dental implant. The dental implant was originally placed in August 2012. Ten months later, the patient presented with a well-circumscribed lesion associated with and covering the implant, at which time the lesion was excised. Four months later, due to recurrence of the lesion, a deeper and wider excisional biopsy with curettage of the adjacent bone was performed. No evidence of recurrence has been reported after 12 months of follow-up. Immunohistochemistry, using the antibody CD68, was performed to investigate the origin of the multinucleated giant cells, with their immunophenotype being similar to those of other giant cell lesions, including central giant cell granuloma, foreign-body reactions, and granulomatous reactions to infectious agents.

scholarly journals Clinical Management of a Peri-Implant Giant Cell Granuloma

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
A. Pacifici ◽  
D. Carbone ◽  
R. Marini ◽  
G. L. Sfasciotti ◽  
L. Pacifici
Keyword(s):  
Giant Cell ◽  
Dental Implant ◽  
Correct Diagnosis ◽  
Excisional Biopsy ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma ◽  
Natural Teeth ◽  
Implant Therapy

Purpose. Implant therapy plays an important role in contemporary dentistry with high rates of long-term success. However, in recent years, the incidence of peri-implantitis and implant failures has significantly increased. The peripheral giant cell granuloma (PGCG) rarely occurs in peri-implant tissues and it is clinically comparable to the lesions associated with natural teeth. Therefore, the study of possible diseases associated with dental implants plays an important role in order to be able to diagnose and treat these conditions.Materials and Methods. This report described a 60-year-old Caucasian male who presented a reddish-purple pedunculated mass, of about 2 cm in diameter, associated with a dental implant and the adjacent natural tooth.Results. An excisional biopsy was performed and the dental implant was not removed. Histological examination provided the diagnosis of PGCG. After 19-month follow-up, there were no signs of recurrence of peri-implantitis around the implant.Conclusion. The correct diagnosis and appropriate surgical treatment of peri-implant giant cell granuloma are very important for a proper management of the lesion in order to preserve the implant prosthetic rehabilitation and prevent recurrences.

scholarly journals Peripheral giant cell granuloma: a case repo

2016 ◽  
Vol 4 (2) ◽  
pp. 44
Author(s):  
Saad Shahnawaz Ahmed ◽  
Hira Zaman ◽  
Fahad Bin Abrar ◽  
Sadia Khalid
Keyword(s):  
Giant Cell ◽  
Stromal Cells ◽  
Unknown Origin ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Cell Hyperplasia ◽  
Peripheral Giant Cell Granuloma ◽  
Good Healing ◽  
Chronic Trauma

Peripheral giant cell granuloma (PGCG) is a common benign gingival lesion in the oral cavity of unknown origin, believed to be stimulated by local irritation or chronic trauma. It is also known as giant cell epulis, giant cell reparative granuloma, or giant-cell hyperplasia, presenting as purplish-red soft tissue nodule clinically and histologically consisting of multinucleated giant cells in a background of mononuclear stromal cells and extravasated red blood cells. This case report describes a 40 year old male previously reported with peripheral giant cell granuloma 2 years back which on excision reoccurred after 3-4 months and persistently growing since then. The gingival lesion between his maxillary central incisors was excised and the Biopsy specimen sent in 10% formalin to histopathological lab and was diagnosed as PGCG. There was good healing of tissue of the surgical site during the 9 months follow-up.

Peripheral Giant Cell Granuloma Associated With Dental Implants: Clinical Case and Literature Review

2012 ◽  
Vol 38 (S1) ◽  
pp. 527-532 ◽  
Author(s):  
Maria A. Peñarrocha-Diago ◽  
Juan Cervera-Ballester ◽  
Laura Maestre-Ferrín ◽  
David Peñarrocha-Oltra
Keyword(s):  
Giant Cell ◽  
Dental Implants ◽  
Histological Study ◽  
Complete Resection ◽  
Fourth Quadrant ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma ◽  
Soft Tissue Complication ◽  
Fixed Prosthesis

Peripheral giant cell granuloma (PGCG) associated to dental implants is a very infrequent peri-implant soft-tissue complication, with only 11 cases recorded in the literature to date. The present study describes a 54-year-old woman presenting a swelling of the alveolar margin in the fourth quadrant in relation to a fixed prosthesis cemented over implants. Treatment consisted of complete resection of the lesion with implantoplasty of the exposed implant threads. The diagnosis of PGCG was confirmed by histological study, and no relapse has been recorded after 12 months of follow-up.

scholarly journals Central giant cell granuloma of the maxilla: a case re-port

2017 ◽  
Vol 5 (2) ◽  
pp. 145
Author(s):  
Najwa Alchalabi ◽  
Hayder Salih ◽  
Ahmed Merza
Keyword(s):  
Giant Cell ◽  
Unusual Case ◽  
Clinical Presentation ◽  
Benign Lesion ◽  
Giant Cell Granuloma ◽  
Case Presentation ◽  
Central Giant Cell Granuloma ◽  
First Choice ◽  
Bone Cortex

Introduction: Central giant-cell is a benign lesion that predominantly involves the bone of the mandible and maxilla with a wide variation of its behavior. Surgery usually is the first choice in treatment of central giant cell granuloma.Case Report: In this case report we present a 29 years-old female with well define swelling on left maxilla. Diagnosis through incisional biopsy showed a central giant cell granuloma. Surgery with curettage was our treatment option with a follow up( 2 years ), No recurrence was reported.Discussion: Information on the maxillary central giant cell granuloma in published studies is insufficient. So here we present our case as unusual case presentation. Differential diagnosis of this case included osteosarcoma (parosteal type) since the tumor clinical presentation in periosteous tissue adjacent to the bone cortex and showed rapid growth. We chose the conventional surgical treatment by simple surgical curettage by mid-face degloving approach to avoid any facial scaring.

scholarly journals Peripheral giant cell granuloma associated with a dental implant: A case report

2021 ◽  
pp. e1049-e1052
Author(s):  
A. Sánchez-Torres ◽  
B. Pérez-Amate ◽  
A. Javier ◽  
I. Cercadillo-Ibarguren ◽  
R. Figueiredo ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Dental Implant ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma

scholarly journals Central Odontogenic Fibroma Accompanied by a Central Giant Cell Granuloma-Like Lesion: Report of a Case and Review of Literature

2022 ◽  
Author(s):  
Monir Moradzadeh Khiavi ◽  
Abbas Karimi ◽  
Hassan Mirmohammad Sadeghi ◽  
Samira Derakhshan ◽  
Seyed Mobin Tafreshi ◽  
...  
Keyword(s):  
Giant Cell ◽  
Benign Lesion ◽  
Excisional Biopsy ◽  
Giant Cells ◽  
Histopathological Analysis ◽  
Giant Cell Granuloma ◽  
Multinucleated Giant Cells ◽  
Central Giant Cell Granuloma ◽  
Odontogenic Fibroma ◽  
Central Odontogenic Fibroma

Central giant cell granuloma (CGCG) is a benign non-neoplastic intraosseous lesion mainly found in the anterior mandible. It is characterized by multinucleated giant cells, representing osteoclasts or macrophages. Central odontogenic fibroma (COF) is an uncommon benign lesion of the jaws. It originates from the odontogenic ectomesenchyme. In rare cases, COF may accompany a CGCG. To date, 49 cases of COF accompanied by CGCG-like lesions have been reported in the literature. In this paper, we present another case of COF-CGCG in a 46-year-old female. The lesion was located in the posterior mandible. Excisional biopsy was carried out, and histopathological analysis revealed multinucleated giant cells with numerous strands of odontogenic epithelium. A literature review of previously reported cases was also performed.  

scholarly journals Peripheral giant cell granuloma – case report

2016 ◽  
Vol 63 (3) ◽  
pp. 139-144
Author(s):  
Slavoljub Tomić ◽  
Bojana Davidović
Keyword(s):  
Giant Cell ◽  
Soft Tissue Tumor ◽  
Oral Lesion ◽  
Giant Cells ◽  
Vertical Position ◽  
Dental Arch ◽  
Giant Cell Granuloma ◽  
Maxillary Canine ◽  
Large Lesion ◽  
Peripheral Giant Cell Granuloma

Abstract Peripheral giant cell granuloma (PGCG) or “Epulis gigantocelularis” is the most common oral lesion that originates from giant cells. It typically manifests in the form of soft tissue tumor purple-red or red-watery color consisting of multinuclear giant cells in the mononuclear stroma and extravascular erythrocytes. This lesion is not considered true neoplasm, rather reactive lesion stimulated by local irritation and trauma. However, the cause is not known with certainty. This paper presents a 13-year-old boy with a large lesion in the region of right maxillary canine that was retained in jaw despite favorable vertical position and available space to accommodate in the dental arch. The lesion was completely removed under local anesthesia and histopathological findings confirmed the diagnosis of PGCG. Postoperative period went without complications. After four months additional surgical procedure was needed due to the recurrence, which after tooth naturally erupted and positioned in the dental arch.

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