scholarly journals Oligopeptide M13 Phage Display in Pathogen Research

Viruses ◽  
2013 ◽  
Vol 5 (10) ◽  
pp. 2531-2545 ◽  
Author(s):  
Jonas Kügler ◽  
Jonas Zantow ◽  
Torsten Meyer ◽  
Michael Hust
Keyword(s):  
Phage Display ◽  
M13 Phage

scholarly journals Selection of Peptides Targeting Helix 31 of Bacterial 16S Ribosomal RNA by Screening M13 Phage-Display Libraries

Molecules ◽  
2011 ◽  
Vol 16 (2) ◽  
pp. 1211-1239 ◽  
Author(s):  
Tek N. Lamichhane ◽  
N. Dinuka Abeydeera ◽  
Anne-Cécile E. Duc ◽  
Philip R. Cunningham ◽  
Christine S. Chow
Keyword(s):  
Phage Display ◽  
Ribosomal Rna ◽  
16S Ribosomal Rna ◽  
Phage Display Libraries ◽  
M13 Phage ◽  
Selection Of

scholarly journals Analysis of peptide‐binding motifs for two disease associated HLA‐DR13 alleles using an M13 phage display library

Immunology ◽  
1996 ◽  
Vol 88 (4) ◽  
pp. 482-486 ◽  
Author(s):  
M. P. DAVENPORT ◽  
C. L. QUINN ◽  
P. VALSASNINI ◽  
F. SINIGAGLIA ◽  
A. V. S. HILL ◽  
...  
Keyword(s):  
Phage Display ◽  
Peptide Binding ◽  
Phage Display Library ◽  
Binding Motifs ◽  
M13 Phage

A target-unrelated peptide in an M13 phage display library traced to an advantageous mutation in the gene II ribosome-binding site

2008 ◽  
Vol 373 (1) ◽  
pp. 88-98 ◽  
Author(s):  
Leighanne A. Brammer ◽  
Benjamin Bolduc ◽  
Jessica L. Kass ◽  
Kristin M. Felice ◽  
Christopher J. Noren ◽  
...  
Keyword(s):  
Phage Display ◽  
Binding Site ◽  
Phage Display Library ◽  
Ribosome Binding Site ◽  
Ribosome Binding ◽  
M13 Phage

Phage Display Selection of P1 Mutants of BPTI Directed against Five Different Serine Proteinases

1999 ◽  
Vol 380 (1) ◽  
Author(s):  
L. Kiczak ◽  
K. Koscielska ◽  
J. Otlewski ◽  
M. Czerwinski ◽  
M. Dadlez
Keyword(s):  
Phage Display ◽  
Trypsin Inhibitor ◽  
Association Constant ◽  
Serine Proteinases ◽  
Wild Type ◽  
Association Energy ◽  
Basic Pancreatic Trypsin Inhibitor ◽  
Pancreatic Trypsin Inhibitor ◽  
M13 Phage ◽  
Selection Of

AbstractThe P1 position of protein inhibitors and oligopeptide substrates determines, to a large extent, association energy with many serine proteinases. To test the agreement of phage display selection with the existing thermodynamic data, a small library of all 20 P1 mutants of basic pancreatic trypsin inhibitor (BPTI) was created, fused to protein III, and displayed on the surface of M13 phage. The wild type of displayed inhibitor monovalently and strongly inhibited trypsin with an association constant of

scholarly journals Design and Screening of M13 Phage Display cDNA Libraries

Molecules ◽  
2011 ◽  
Vol 16 (2) ◽  
pp. 1667-1681 ◽  
Author(s):  
Yuliya Georgieva ◽  
Zoltán Konthur
Keyword(s):  
Phage Display ◽  
Cdna Libraries ◽  
M13 Phage

Phage survival: The biodegradability of M13 phage display libraryin vitro

2012 ◽  
Vol 59 (6) ◽  
pp. 490-494 ◽  
Author(s):  
L'ubomíra Tóthová ◽  
Janka Bábíčková ◽  
Peter Celec
Keyword(s):  
Phage Display ◽  
M13 Phage

scholarly journals Selection of peptides binding to metallic borides by screening M13 phage display libraries

2014 ◽  
Vol 14 (1) ◽  
pp. 12 ◽  
Author(s):  
Martin Ploss ◽  
Sandra J Facey ◽  
Carina Bruhn ◽  
Limor Zemel ◽  
Kathrin Hofmann ◽  
...  
Keyword(s):  
Phage Display ◽  
Phage Display Libraries ◽  
M13 Phage ◽  
Selection Of

scholarly journals M13 phage display to identify a permeating peptide against hyperconcentrated mucin

2019 ◽  
Author(s):  
Jasmim Leal ◽  
Tony Dong ◽  
Feng Gao ◽  
Melissa Soto ◽  
Hugh D.C. Smyth ◽  
...  
Keyword(s):  
Phage Display ◽  
Physicochemical Properties ◽  
Initial Study ◽  
Initial Finding ◽  
Chemical Complexity ◽  
Mucus Penetration ◽  
Hydrophilic Peptide ◽  
M13 Phage ◽  
Mucus Barrier ◽  
Surface Chemistries

ABSTRACTMucus is an impregnable barrier for drug delivery across the epithelia for treatment of mucosal-associated diseases. While current carriers are promising for mucus penetration, their surface chemistries do not possess chemical complexity to probe and identify optimal physicochemical properties desired for mucus penetration. As initial study, we use M13 phage display presenting random peptides to select peptides that can facilitate permeation through hyperconcentrated mucin. Here, a net-neutral charge, hydrophilic peptide was identified to facilitate transport of phage and fluorophore conjugates through mucin barrier compared to controls. This initial finding warrants further study to understand how composition and spatial distribution of physicochemical properties of peptides can be optimized to improve transport across the mucus barrier.

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