scholarly journals Why New Vaccines for the Control of Ectoparasite Vectors Have Not Been Registered and Commercialized?

Vaccines ◽  
2019 ◽  
Vol 7 (3) ◽  
pp. 75 ◽  
Author(s):  
José de la Fuente ◽  
Agustín Estrada-Peña

The prevention and control of vector-borne diseases is a priority for improving global health. Despite recent advances in the characterization of ectoparasite-host-pathogen molecular interactions, vaccines are not available for most ectoparasites and vector-borne diseases that cause millions of deaths yearly. In this paper, in response to the question of why new vaccines for the control of ectoparasite vectors have not been registered and commercialized, and to contribute developing new effective vaccines against ectoparasite vectors, we propose challenges and approaches to be addressed.

2020 ◽  
Vol 222 (Supplement_8) ◽  
pp. S726-S731
Author(s):  
Carl Abelardo T Antonio ◽  
Amiel Nazer C Bermudez ◽  
Kim L Cochon ◽  
Ma Sophia Graciela L Reyes ◽  
Chelseah Denise H Torres ◽  
...  

Abstract Background Intersectoral collaboration in the context of the prevention and control of vector-borne diseases has been broadly described in both the literature and the current global strategy by the World Health Organization. Our aim was to develop a framework that will distill the currently known multiple models of collaboration. Methods Qualitative content analysis and logic modeling of data abstracted from 69 studies included in a scoping review done by the authors were used to develop 9 recommendation statements that summarized the composition and attributes of multisectoral approaches, which were then subjected to a modified Delphi process with 6 experts in the fields of health policy and infectious diseases. Results Consensus for all statements was achieved during the first round. The recommendation statements were on (1–3) sectoral engagement to supplement government efforts and augment public financing; (4) development of interventions for most systems levels; (5–6) investment in human resource, including training; (7–8) intersectoral action to implement strategies and ensure sustainability of initiatives; and (9) research to support prevention and control efforts. Conclusions The core of intersectoral action to prevent vector-borne diseases is collaboration among multiple stakeholders to develop, implement, and evaluate initiatives at multiple levels of intervention.


2019 ◽  
Vol 53 (4) ◽  
Author(s):  
Ma. Sophia Graciela L. Reyes ◽  
Chelseah Denise H. Torres ◽  
Amiel Nazer C. Bermudez ◽  
Kim L. Cochon ◽  
Evalyn A. Roxas ◽  
...  

Objectives. This scoping review aimed to support a landscape analysis to identify lessons learned about intersectoral collaborations (ISCs) by describing their existing models in the context of dengue, malaria and yellow fever. Methods. A scoping review following the methodology of Joanna Briggs Institute was performed using the following inclusion criteria: studies involving humans; studies discussing intersectoral collaborations, malaria/dengue/yellow fever, and prevention or control at any level; and studies in countries endemic for the aforementioned diseases. Studies were screened using Covidence, while data were extracted using NVivo. Results. Of the 7,535 records retrieved, 69 were included in the qualitative analysis. Most ISCs were initiated by multilateral organizations and ministries of health, and none by communities. Strategies included advocacy, health education, research, public health measures, resource mobilization, service delivery and training; mostly employed on a community level. Monitoring and evaluation were mostly formative, ongoing, and participatory. Gaps included administrative and policy barriers, resource shortages, and inadequate research and training. Conclusions. Multiple models of ISC exist in the literature. There is a need to develop a comprehensive framework for an effective and sustainable multisectoral approach for the prevention and control of VBDs ensuring adequate resources, active stakeholders, and strategies that span the entire socio-ecological spectrum.


2007 ◽  
Vol 84 (S1) ◽  
pp. 65-74 ◽  
Author(s):  
Annette M. David ◽  
Susan P. Mercado ◽  
Daniel Becker ◽  
Katia Edmundo ◽  
Frederick Mugisha

2020 ◽  
Vol 222 (Supplement_8) ◽  
pp. S695-S700
Author(s):  
Florence Fouque ◽  
Karin Gross ◽  
Zee Leung ◽  
Konstantina Boutsika

Abstract The Swiss Development Cooperation, Canada’s International Development Research Centre, the Swiss Tropical Public Health Institute, and the UNICEF/United Nations Development Programme (UNDP)/World Bank/World Health Organization (WHO) Special Programme for Research and Training in Tropical Diseases (TDR) collaborated on a project to review, understand and promote the use of multisectoral approaches (MSAs) in the prevention and control of vector-borne diseases (VBDs). The objectives of the project were to support a landscape analysis of how MSAs have been used in the prevention and control of VBDs; to develop a theoretical framework for guiding the implementation of interventions; and to test the recommendations in real-life conditions. To realize these objectives, the project supported several activities, including commissioning a series of scientific reviews on MSAs in 5 thematic areas, sharing the key findings of these reviews in workshops and events, and developing a guidance framework for the implementation of MSAs. These activities have produced the theoretical framework that will be tested in real-life conditions through the support of case studies. The collaboration on implementing multisectoral activities against VBDs will continue among TDR, the Swiss Tropical Public Health Institute, and new partners such as the WHO Water Sanitation and Hygiene Group, UNDP, and UN-Habitat, in order to face the challenges identified and propose solutions tailored to specific contexts. The prevention and control of VBDs require strong and adapted MSAs with the full participation of all relevant sectors.


2020 ◽  
Vol 14 (4) ◽  
pp. e0008136
Author(s):  
Vaitiare Mulderij-Jansen ◽  
Jelte Elsinga ◽  
Izzy Gerstenbluth ◽  
Ashley Duits ◽  
Adriana Tami ◽  
...  

2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Christian Dagenais ◽  
Stéphanie Degroote ◽  
Mariam Otmani Del Barrio ◽  
Clara Bermudez-Tamayo ◽  
Valéry Ridde

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