scholarly journals CLINICAL AND FUNCTIONAL DISORDERS OF CARDIORESPIRATORY SYSTEM IN PATIENTS WITH COVID-19

Author(s):  
A.Yu. Smirnova ◽  
V.V. Gnoevykh ◽  
Yu.A. Shorokhova ◽  
N.G. Chernova ◽  
V.A. Serov ◽  
...  

The goal of the paper is to range information about early and delayed clinical and functional disorders of the respiratory and cardiovascular systems after COVID-19. The review focuses on clinical and functional diagnostic methods (laboratory, instrumental and radiation) of disorders of the cardiovascular and respiratory systems in patients after COVID-19. At the moment, enough data has been accumulated confirming early and aftereffect of COVID-19. The need for further rehabilitation may be caused by the presence and severity of clinical and functional disorders of the respiratory and cardiovascular systems. Key words: coronavirus disease (COVID-19), impaired respiratory function and diffusion lung capacity, acute myocardial injury, electrical myocardium instability. Цель – систематизировать сведения о ранних и отсроченных клинико-функциональных нарушениях дыхательной и сердечно-сосудистой систем после перенесенной коронавирусной инфекции. В обзоре основное внимание уделено клинико-функциональным методам диагностики (лабораторным, инструментальным и лучевым) нарушений сердечно-сосудистой и дыхательной систем у пациентов, перенесших COVID-19. На данный момент накоплено достаточно данных, подтверждающих наличие ранних и отсроченных последствий новой коронавирусной инфекции. Необходимость дальнейшей реабилитации может быть обусловлена наличием и тяжестью клинико-функциональных нарушений со стороны органов дыхания и сердечно-сосудистой системы. Ключевые слова: новая коронавирусная инфекция (COVID-19), нарушения функции внешнего дыхания и диффузионной способности легких, острое повреждение миокарда, электрическая нестабильность миокарда.

2020 ◽  
Vol 26 (3) ◽  
pp. 270-276
Author(s):  
O. N. Dzhioeva ◽  
O. M. Drapkina

Given the risk of cardiovascular complications in COVID-19, including exacerbation of pre-existing heart disease, acute myocardial injury, and drug-related cardiac arrhythmias, echocardiography (ECHO) is one of the main diagnostic methods for examining patients with suspected infection or confirmed disease. The article presents the main statements regarding transthoracic ECHO during a pandemic. The main issues related to the FOCUS ECHO are described, as it may play important diagnostic role in case of suspected myocarditis, which can be one of the manifestations of heart damage of coronavirus infection.


1958 ◽  
Vol 56 (6) ◽  
pp. 926-928 ◽  
Author(s):  
Robert S. Fraser ◽  
Richard E. Rossall

2013 ◽  
Vol 20 (1) ◽  
pp. 60-62
Author(s):  
WC Lin ◽  
YM Weng ◽  
YL Chan ◽  
H Chang ◽  
SL Huang ◽  
...  

Cytotherapy ◽  
2005 ◽  
Vol 7 (3) ◽  
pp. 282-291 ◽  
Author(s):  
B.M. Strem ◽  
M. Zhu ◽  
Z. Alfonso ◽  
E.J. Daniels ◽  
R. Schreiber ◽  
...  

2018 ◽  
Vol 123 (12) ◽  
pp. 926-934 ◽  
Author(s):  
Carlo Tessa ◽  
Jacopo Del Meglio ◽  
Alessio Lilli ◽  
Stefano Diciotti ◽  
Luca Salvatori ◽  
...  

2019 ◽  
Vol 476 (2) ◽  
pp. 179-194 ◽  
Author(s):  
Katarzyna Michaud ◽  
◽  
Cristina Basso ◽  
Giulia d’Amati ◽  
Carla Giordano ◽  
...  

Abstract Ischemic heart disease is one of the leading causes of morbidity and death worldwide. Consequently, myocardial infarctions are often encountered in clinical and forensic autopsies, and diagnosis can be challenging, especially in the absence of an acute coronary occlusion. Precise histopathological identification and timing of myocardial infarction in humans often remains uncertain while it can be of crucial importance, especially in a forensic setting when third person involvement or medical responsibilities are in question. A proper post-mortem diagnosis requires not only up-to-date knowledge of the ischemic coronary and myocardial pathology, but also a correct interpretation of such findings in relation to the clinical scenario of the deceased. For these reasons, it is important for pathologists to be familiar with the different clinically defined types of myocardial infarction and to discriminate myocardial infarction from other forms of myocardial injury. This article reviews present knowledge and post-mortem diagnostic methods, including post-mortem imaging, to reveal the different types of myocardial injury and the clinical-pathological correlations with currently defined types of myocardial infarction.


Heart ◽  
2020 ◽  
Vol 106 (15) ◽  
pp. 1154-1159 ◽  
Author(s):  
Jia-Fu Wei ◽  
Fang-Yang Huang ◽  
Tian-Yuan Xiong ◽  
Qi Liu ◽  
Hong Chen ◽  
...  

ObjectiveWe sought to explore the prevalence and immediate clinical implications of acute myocardial injury in a cohort of patients with COVID-19 in a region of China where medical resources are less stressed than in Wuhan (the epicentre of the pandemic).MethodsWe prospectively assessed the medical records, laboratory results, chest CT images and use of medication in a cohort of patients presenting to two designated covid-19 treatment centres in Sichuan, China. Outcomes of interest included death, admission to an intensive care unit (ICU), need for mechanical ventilation, treatment with vasoactive agents and classification of disease severity. Acute myocardial injury was defined by a value of high-sensitivity troponin T (hs-TnT) greater than the normal upper limit.ResultsA total of 101 cases were enrolled from January to 10 March 2020 (average age 49 years, IQR 34–62 years). Acute myocardial injury was present in 15.8% of patients, nearly half of whom had a hs-TnT value fivefold greater than the normal upper limit. Patients with acute myocardial injury were older, with a higher prevalence of pre-existing cardiovascular disease and more likely to require ICU admission (62.5% vs 24.7%, p=0.003), mechanical ventilation (43.5% vs 4.7%, p<0.001) and treatment with vasoactive agents (31.2% vs 0%, p<0.001). Log hs-TnT was associated with disease severity (OR 6.63, 95% CI 2.24 to 19.65), and all of the three deaths occurred in patients with acute myocardial injury.ConclusionAcute myocardial injury is common in patients with COVID-19 and is associated with adverse prognosis.


2020 ◽  
Vol 305 ◽  
pp. 58-60 ◽  
Author(s):  
Yiannis S. Chatzizisis ◽  
Ganesh Gajanan ◽  
Deepak L. Bhatt ◽  
George Dangas ◽  
Thomas Porter

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