Specification for microform readers. Microform reader resolution test film

2015 ◽  
Keyword(s):  
Test Film

scholarly journals Design Optimization and In Vitro-In Vivo Evaluation of Orally Dissolving Strips of Clobazam

2014 ◽  
Vol 2014 ◽  
pp. 1-15 ◽  
Author(s):  
Rajni Bala ◽  
Sushil Khanna ◽  
Pravin Pawar
Keyword(s):  
Tensile Strength ◽  
Drug Release ◽  
Content Uniformity ◽  
In Vivo Evaluation ◽  
Disintegration Time ◽  
Significant Difference ◽  
Film Formulation ◽  
Test Film

Clobazam orally dissolving strips were prepared by solvent casting method. A full 32 factorial design was applied for optimization using different concentration of film forming polymer and disintegrating agent as independent variable and disintegration time, % cumulative drug release, and tensile strength as dependent variable. In addition the prepared films were also evaluated for surface pH, folding endurance, and content uniformity. The optimized film formulation showing the maximum in vitro drug release, satisfactory in vitro disintegration time, and tensile strength was selected for bioavailability study and compared with a reference marketed product (frisium5 tablets) in rabbits. Formulation (F6) was selected by the Design-expert software which exhibited DT (24 sec), TS (2.85 N/cm2), and in vitro drug release (96.6%). Statistical evaluation revealed no significant difference between the bioavailability parameters of the test film (F6) and the reference product. The mean ratio values (test/reference) of Cmax (95.87%), tmax (71.42%), AUC0−t (98.125%), and AUC0−∞ (99.213%) indicated that the two formulae exhibited comparable plasma level-time profiles.

III. COMPARISON OF THE EFFECTS OF MARIJUANA AND ALCOHOL ON SIMULATED DRIVING PERFORMANCE

PEDIATRICS ◽  
1970 ◽  
Vol 45 (1) ◽  
pp. 131-131
Author(s):  
A. Crancer ◽  
J. D. Dille ◽  
J. C. Delay ◽  
J. C. Wallace ◽  
M. D. Haykin
Keyword(s):  
Blood Concentration ◽  
Motor Vehicle ◽  
Driving Performance ◽  
Training Simulator ◽  
Driver Training ◽  
Simulated Driving ◽  
Minute Period ◽  
Test Film

The authors studied simulated driving performance of a group of adults who were experienced marijuana smokers, familiar with the effects of alcohol, who were licensed motor vehicle operators, and were engaged in educational or vocational pursuit. Simulated driving performance was studied in a darkened chamber with the subjects at the controls of a driver-training simulator containing control and instrument equipment relevant to driving, and facing a screen upon which a test film was projected. The effects of marijuana (two cigarettes totalling 1.7 gm over a 30-minute period) , alcohol to 0.10% blood concentration (about 6 oz 86-proof liquor for a 120 lb subject), and no treatment were compared.

Effect of Hydrated Salt Additives on Film Boiling Behavior at Vapor Film Collapse

2008 ◽  
Author(s):  
Takahiro Arai ◽  
Masahiro Furuya
Keyword(s):  
High Speed ◽  
Video Camera ◽  
Film Boiling ◽  
Vapor Film ◽  
Quenching Temperature ◽  
Steel Sphere ◽  
Digital Video Camera ◽  
Collapse Temperature ◽  
Test Film ◽  
Film Collapse

A high-temperature stainless-steel sphere was immersed into various salt solutions to test film boiling behavior at vapor film collapse. The film boiling behavior around the sphere was observed with a high-speed digital-video camera. Because salt additives enhanced condensation heat transfer, the observed vapor film was thinner. Surface temperature of the sphere was measured. Salt additives increased the quenching (vapor film collapse) temperature, because frequency of direct contact between sphere surface and coolant increased. Quenching temperature rises with increased salt concentration. The quenching temperature, however, approaches a constant value when the slat concentration is close to its saturation concentration. The quenching temperature is well correlated with ion molar concentration, which is a number density of ions, regardless of the type of hydrated salts.

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