Water quality. Determination of certain organochlorine insecticides, polychlorinated biphenyls and chlorobenzenes. Gas chromatographic method after liquid-liquid extraction

2015 ◽  
Keyword(s):  
Water Quality ◽  
Polychlorinated Biphenyls ◽  
Chromatographic Method ◽  
Liquid Extraction ◽  
Liquid Liquid Extraction ◽  
Organochlorine Insecticides ◽  
Gas Chromatographic Method

scholarly journals Determination of Nitroimidazoles and Their Metabolites in Swine Tissues by Liquid Chromatography

2003 ◽  
Vol 86 (3) ◽  
pp. 505-509 ◽  
Author(s):  
Jianzhong Shen ◽  
Yue Yhang ◽  
Suxia Zhang ◽  
Shuangyang Ding ◽  
Xinhua Xiang
Keyword(s):  
Chromatographic Method ◽  
Solid Phase ◽  
Liquid Extraction ◽  
Phase Extraction ◽  
Liquid Liquid Extraction ◽  
Liquid Chromatographic Method ◽  
Swine Tissue ◽  
Liquid Chromatographic ◽  
Sensitive Method

Abstract A liquid chromatographic method was developed for determination of metronidazole (MNZ), ronidazole (RNZ), dimetridazole (DMZ), and 2-hydroxymethyl-1-methyl-5-nitroimidazole (DMZOH) in swine tissue. After extraction with ethyl acetate and evaporation, the nitroimidazoles were redissolved in hydrochloric acid. Hexane was used in the liquid–liquid extraction to remove fat. An Oasis® HLB solid-phase extraction was performed after neutralization of the acidic extract. The limits of detection were 1.0–2.0 μg/kg for DMZOH, MNZ, RNZ, and DMZ in muscle and liver. Average recoveries ranged from 80.1 to 83.9% in muscle fortified at 10, 20, and 50 μg/kg; average re-coveries in liver ranged from 78.9 to 82.3%. The procedure provides a simple and sensitive method for monitoring DMZOH, MNZ, RNZ, and DMZ residues in swine tissues.

scholarly journals Selective Liquid Chromatographic Method for Determination of Fluoxetine in Plasma

2001 ◽  
Vol 84 (6) ◽  
pp. 1735-1738 ◽  
Author(s):  
Afshin Zarghi ◽  
Abbas Kebriaeezadeh ◽  
Reza Ahmadkhaniha ◽  
Maryam Akhgari ◽  
Nooshin Rastkari
Keyword(s):  
Mobile Phase ◽  
Chromatographic Method ◽  
Antidepressant Drugs ◽  
Liquid Extraction ◽  
Tricyclic Antidepressant ◽  
Liquid Liquid Extraction ◽  
Coefficients Of Variation ◽  
Liquid Chromatographic Method ◽  
Liquid Chromatographic

Abstract A selective and sensitive liquid chromatographic method was developed for the determination of fluoxetine (FLU) in plasma. FLU was isolated from plasma by liquid–liquid extraction. The chromatographic separation was performed on an analytical 250 × 3.9 mm id Novapak C18 column (4 μm particle size) with an isocratic mobile phase consisting of phosphate buffer–acetonitrile–methanol–triethylamine (58 + 30 + 10 + 2, v/v) adjusted to pH 7. Using UV detection at 226 nm, the detection limit for FLU in plasma was 3 ng/mL. No interferences were found with tricyclic antidepressant drugs, which allows this method to be used in clinical studies. The calibration curve was linear over the concentration range of 10–200 ng/mL. The average recovery was about 80% for plasma. The inter- and intraday assay coefficients of variation were <8%.

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