Faculty Opinions recommendation of Manumycin A and its analogues are irreversible inhibitors of neutral sphingomyelinase.

2002 ◽  
Author(s):  
Stefan Bräse
Keyword(s):  
Neutral Sphingomyelinase ◽  
Irreversible Inhibitors

Manumycin A and Its Analogues Are Irreversible Inhibitors of Neutral Sphingomyelinase

ChemBioChem ◽  
2001 ◽  
Vol 2 (2) ◽  
pp. 141-143 ◽  
Author(s):  
Christoph Arenz ◽  
Michael Thutewohl ◽  
Oliver Block ◽  
Herbert Waldmann ◽  
Hans-Josef Altenbach ◽  
...  
Keyword(s):  
Neutral Sphingomyelinase ◽  
Irreversible Inhibitors

Synthesis and properties of oxytocin analogues acting as irreversible inhibitors of the uterotonic response to oxytocin

1979 ◽  
Vol 44 (8) ◽  
pp. 2573-2582 ◽  
Author(s):  
Michal Lebl ◽  
Vera Bojanovska ◽  
Tomislav Barth ◽  
Karel Jošt
Keyword(s):  
Glutamic Acid ◽  
Active Esters ◽  
Irreversible Inhibitors ◽  
Reactive Groups ◽  
Chemical Character

A series of compounds containing reactive groups of different chemical character was synthetized from [4-glutamic acid]deamino-1-carba-oxytocin or from [2-O-methyltyrosine, 4-glutamic acid]deamino-1-carba-oxytocin. The analogues acted as specific irreversible inhibitors of the uterotonic response to oxytocin. Active esters of the initial compounds were the most effective inhibitors.

scholarly journals Regulatory T cells reduce endothelial neutral sphingomyelinase 2 to prevent T cell migration into tumors

2021 ◽  
Author(s):  
Paulina Akeus ◽  
Louis Szeponik ◽  
Veronica Langenes ◽  
Viktoria Karlsson ◽  
Patrik Sundström ◽  
...  
Keyword(s):  
T Cells ◽  
Cell Migration ◽  
T Cell ◽  
Regulatory T Cells ◽  
Neutral Sphingomyelinase ◽  
T Cell Migration

scholarly journals Physiological functions and therapeutic applications of neutral sphingomyelinase and acid sphingomyelinase

2021 ◽  
Vol 139 ◽  
pp. 111610
Author(s):  
Hongjiao Xiang ◽  
Shengjie Jin ◽  
Fenglang Tan ◽  
Yifan Xu ◽  
Yifei Lu ◽  
...  
Keyword(s):  
Acid Sphingomyelinase ◽  
Physiological Functions ◽  
Therapeutic Applications ◽  
Neutral Sphingomyelinase

scholarly journals Neutral sphingomyelinase‐2 and cardiometabolic diseases

2021 ◽  
Author(s):  
Sardar Sindhu ◽  
Yat Hei Leung ◽  
Hossein Arefanian ◽  
S. R. Murthy Madiraju ◽  
Fahd Al‐Mulla ◽  
...  
Keyword(s):  
Cardiometabolic Diseases ◽  
Neutral Sphingomyelinase
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