Faculty Opinions recommendation of Functional conversion between A-type and delayed rectifier K+ channels by membrane lipids.

Author(s):  
Sharona Gordon
2018 ◽  
Vol 17 (4) ◽  
pp. 255-260 ◽  
Author(s):  
Feng Gao ◽  
Lin-Jie Xu ◽  
Yuan Zhao ◽  
Xing-Huai Sun ◽  
Zhongfeng Wang

Background & Objective: Müller cell is the major type of glial cell in the vertebrate retina. Müller cells express various types of K+ channels, such as inwardly rectifying K+ (Kir) channels, big conductance Ca2+-activated K+ (BKCa) channels, delayed rectifier K+ channels (KDR), and transient A-type K+ channels. These K+ channels play important roles in maintaining physiological functions of Müller cells. Under some retinal pathological conditions, the changed expression and functions of K+ channels may contribute to retinal pathogenesis. Conclusion: In this article, we reviewed the physiological properties of K+ channels in retinal Müller cells and the functional changes of these channels in retinal disorders.


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Sylvie Chevalier ◽  
Olivier Lesouhaitier ◽  
Nicole Orange ◽  
Marc G.J. Feuilloley ◽  
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1999 ◽  
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Stephen J. Free ◽  
Satpal Singh

Nature ◽  
2008 ◽  
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Neuroscience ◽  
2005 ◽  
Vol 133 (4) ◽  
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...  
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