Faculty Opinions recommendation of Nur, a nickel-responsive regulator of the Fur family, regulates superoxide dismutases and nickel transport in Streptomyces coelicolor.

Author(s):  
John Helmann
1999 ◽  
Vol 181 (23) ◽  
pp. 7381-7384 ◽  
Author(s):  
Hye-Jung Chung ◽  
Jae-Hyun Choi ◽  
Eun-Ja Kim ◽  
You-Hee Cho ◽  
Jung-Hye Roe

ABSTRACT In Streptomyces coelicolor, transcription of thesodF genes, encoding Fe-containing superoxide dismutases, is negatively regulated by nickel. Gel mobility shift assays withsodF1 promoter fragments and cell extracts from the A3(2) strain indicate the presence of a nickel-responsive DNA-binding protein, most likely a transcriptional repressor. The boundary for the Ni-responsive cis-acting region was identified both in vitro and vivo. Ni does not regulate the level of the putative repressor but only the binding competence of this protein.


2006 ◽  
Vol 59 (6) ◽  
pp. 1848-1858 ◽  
Author(s):  
Bo-Eun Ahn ◽  
Joonseok Cha ◽  
Eun-Jin Lee ◽  
Ah-Reum Han ◽  
Charles J. Thompson ◽  
...  

1994 ◽  
Vol 92 (3) ◽  
pp. 443-450 ◽  
Author(s):  
Steffen Streller ◽  
Stanislaw Karpinski ◽  
Jan-Erik Hallgren ◽  
Gunnar Wingsle

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