Faculty Opinions recommendation of Staphylococcus aureus small colony variants in prosthetic joint infection.

Author(s):  
Jordi Vila
Author(s):  
Guilherme Loss ◽  
Patricia Martins Simões ◽  
Florent Valour ◽  
Marina Farrel Cortês ◽  
Luiz Gonzaga ◽  
...  

2021 ◽  
pp. 104854
Author(s):  
Diana Fernández-Rodríguez ◽  
Claudia Adriana Colín-Castro ◽  
Melissa Hernández-Durán ◽  
Luis Esaú López-Jácome ◽  
Rafael Franco-Cendejas

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1182
Author(s):  
Claudia Ramirez-Sanchez ◽  
Francis Gonzales ◽  
Maureen Buckley ◽  
Biswajit Biswas ◽  
Matthew Henry ◽  
...  

Successful joint replacement is a life-enhancing procedure with significant growth in the past decade. Prosthetic joint infection occurs rarely; it is a biofilm-based infection that is poorly responsive to antibiotic alone. Recent interest in bacteriophage therapy has made it possible to treat some biofilm-based infections, as well as those caused by multidrug-resistant pathogens, successfully when conventional antibiotic therapy has failed. Here, we describe the case of a 61-year-old woman who was successfully treated after a second cycle of bacteriophage therapy administered at the time of a two-stage exchange procedure for a persistent methicillin-sensitive Staphylococcus aureus (MSSA) prosthetic knee-joint infection. We highlight the safety and efficacy of both intravenous and intra-articular infusions of bacteriophage therapy, a successful outcome with a single lytic phage, and the development of serum neutralization with prolonged treatment.


2015 ◽  
Vol 82 (2) ◽  
pp. 177-178 ◽  
Author(s):  
Kerryl E. Greenwood-Quaintance ◽  
Peggy Kohner ◽  
Douglas R. Osmon ◽  
Abinash Virk ◽  
Robin Patel

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