Faculty Opinions recommendation of The immunoglobulin heavy chain constant region affects kinetic and thermodynamic parameters of antibody variable region interactions with antigen.

2007 ◽  
Author(s):  
David Kranz
Keyword(s):  
Thermodynamic Parameters ◽  
Heavy Chain ◽  
Variable Region ◽  
Immunoglobulin Heavy Chain ◽  
Constant Region ◽  
Kinetic And Thermodynamic Parameters ◽  
Heavy Chain Constant Region

scholarly journals Physical Mapping of the Bovine Immunoglobulin Heavy Chain Constant Region Gene Locus

2003 ◽  
Vol 278 (37) ◽  
pp. 35024-35032 ◽  
Author(s):  
Yaofeng Zhao ◽  
Imre Kacskovics ◽  
Hodjattallah Rabbani ◽  
Lennart Hammarström
Keyword(s):  
Heavy Chain ◽  
Physical Mapping ◽  
Gene Locus ◽  
Immunoglobulin Heavy Chain ◽  
Constant Region ◽  
Region Gene ◽  
Constant Region Gene ◽  
Heavy Chain Constant Region ◽  
Bovine Immunoglobulin

Segregation of immunoglobulin heavy chain constant region genes in multiple sclerosis sibling pairs

1993 ◽  
Vol 42 (1) ◽  
pp. 113-116 ◽  
Author(s):  
John S. Yu ◽  
Janardan P. Pandey ◽  
Luca Massacesi ◽  
Robin Lincoln ◽  
Koichiro Usuku ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Heavy Chain ◽  
Immunoglobulin Heavy Chain ◽  
Constant Region ◽  
Sibling Pairs ◽  
Heavy Chain Constant Region

Physical mapping of the giant panda immunoglobulin heavy chain constant region genes

2007 ◽  
Vol 31 (10) ◽  
pp. 1034-1049 ◽  
Author(s):  
Zhihui Zhao ◽  
Yaofeng Zhao ◽  
Qiang Pan-Hammarström ◽  
Wei Liu ◽  
Zhaoliang Liu ◽  
...  
Keyword(s):  
Heavy Chain ◽  
Physical Mapping ◽  
Giant Panda ◽  
Immunoglobulin Heavy Chain ◽  
Constant Region ◽  
Heavy Chain Constant Region

scholarly journals The immunoglobulin heavy chain locus contains another B-cell-specific 3' enhancer close to the alpha constant region.

1993 ◽  
Vol 13 (3) ◽  
pp. 1547-1553 ◽  
Author(s):  
P Matthias ◽  
D Baltimore
Keyword(s):  
Transcription Factors ◽  
B Cell ◽  
Heavy Chain ◽  
Variable Region ◽  
Immunoglobulin Heavy Chain ◽  
Immunoglobulin Genes ◽  
Constant Region ◽  
Transcriptional Enhancer ◽  
Additional Control ◽  
Complex Regulation

The transcription of immunoglobulin genes is controlled by variable region promoters and by enhancers, both of which are lymphoid specific. Because immunoglobulin genes are subject to an extremely complex regulation, we anticipated that there might be additional control elements for these genes. We therefore sought additional enhancers and demonstrate here that there is indeed another weak transcriptional enhancer just 3' to the mouse alpha constant region. This novel immunoglobulin enhancer is lymphoid specific and at two positions can bind members of the Oct family of transcription factors.

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