Faculty Opinions recommendation of Altered gene expression and function of peripheral blood natural killer cells in children with autism.

2008 ◽  
Author(s):  
Isaac Kohane
Keyword(s):  
Gene Expression ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Children With Autism ◽  
Killer Cells ◽  
Altered Gene Expression ◽  
Altered Gene ◽  
And Function

scholarly journals Altered gene expression and function of peripheral blood natural killer cells in children with autism

2009 ◽  
Vol 23 (1) ◽  
pp. 124-133 ◽  
Author(s):  
Amanda M. Enstrom ◽  
Lisa Lit ◽  
Charity E. Onore ◽  
Jeff P. Gregg ◽  
Robin L. Hansen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Children With Autism ◽  
Killer Cells ◽  
Altered Gene Expression ◽  
Altered Gene ◽  
And Function

scholarly journals Glucocorticoid receptor expression on circulating leukocytes differs between healthy male and female adults

2017 ◽  
Vol 1 (2) ◽  
pp. 108-114 ◽  
Author(s):  
Kim D. Lu ◽  
Shlomit Radom-Aizik ◽  
Fadia Haddad ◽  
Frank Zaldivar ◽  
Monica Kraft ◽  
...  
Keyword(s):  
Gene Expression ◽  
Flow Cytometry ◽  
Sexual Dimorphism ◽  
Natural Killer Cells ◽  
Glucocorticoid Receptor ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Healthy Adults ◽  
Peripheral Blood Mononuclear ◽  
Killer Cells

IntroductionThe glucocorticoid receptor (GR) is a key receptor involved in inflammatory responses and is influenced by sex steroids. This study measured GR expression on circulating leukocyte subtypes in males and females.MethodsA total of 23 healthy adults (12 female) participated in this study. GR expression was measured in leukocyte subtypes using flow cytometry. Peripheral blood mononuclear cell (PBMC) gene expression of GR (NR3C1), GR β, TGF-β1 and 2, and glucocorticoid-induced leucine zipper (GILZ) were determined by real-time polymerase chain reaction.ResultsLeukocyte GR was lower in females, particularly in granulocytes, natural killer cells, and peripheral blood mononuclear cells (p≤0.01). GR protein expression was different across leukocyte subtypes, with higher expression in eosinophils compared with granulocytes, T lymphocytes, and natural killer cells (p<0.05). There was higher gene expression of GR β in males (p=0.03).ConclusionsThis is the first study to identify sexual dimorphism in GR expression in healthy adults using flow cytometry. These results may begin to explain the sexual dimorphism seen in many diseases and sex differences in glucocorticoid responsiveness.

Peripheral blood natural killer cells activation status determined by CD69 upregulation predicts implantation outcome in IVF

Immunobiology ◽  
2014 ◽  
Vol 219 (3) ◽  
pp. 167-171 ◽  
Author(s):  
Boris V. Dons’koi ◽  
Viktor P. Chernyshov ◽  
Vera Y. Sirenko ◽  
Galina V. Strelko ◽  
Dariia V. Osypchuk
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Killer Cells ◽  
Activation Status

Fraction of the peripheral blood concentration of CD56+/CD16−/CD3− cells in total natural killer cells as an indication of fertility and infertility

2003 ◽  
Vol 80 ◽  
pp. 691-697 ◽  
Author(s):  
Vassiliki I Michou ◽  
Panagiotis Kanavaros ◽  
Vassilis Athanassiou ◽  
George B Chronis ◽  
Stelios Stabamas ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Blood Concentration ◽  
Killer Cells

scholarly journals Human natural killer cells: their origin, receptors and function

2002 ◽  
Vol 32 (5) ◽  
pp. 1205 ◽  
Author(s):  
Lorenzo Moretta ◽  
Cristina Bottino ◽  
Daniela Pende ◽  
Maria Cristina Mingari ◽  
Roberto Biassoni ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Killer Cells ◽  
Human Natural Killer Cells ◽  
And Function

scholarly journals PB2387 CD56 BRIGHT/CD16- NATURAL KILLER CELLS COUNTS ARE HIGHER IN THE UMBILICAL CORD BLOOD THAN IN THE PERIPHERAL BLOOD FROM ADULTS

HemaSphere ◽  
2019 ◽  
Vol 3 (S1) ◽  
pp. 1062
Author(s):  
M. Barbosa ◽  
V. Molla ◽  
A. Mendroni Junior ◽  
M. Goncalves ◽  
E. Kimura ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Cord Blood ◽  
Natural Killer ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Peripheral Blood ◽  
Killer Cells
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