Faculty Opinions recommendation of Determinants of symptom pattern in idiopathic severely delayed gastric emptying: gastric emptying rate or proximal stomach dysfunction?

2006 ◽  
Author(s):  
Klaus Bielefeldt
Keyword(s):  
Gastric Emptying ◽  
Delayed Gastric Emptying ◽  
Proximal Stomach ◽  
Gastric Emptying Rate ◽  
Symptom Pattern

scholarly journals Electrogastrography in Delayed Gastric Emptying

2017 ◽  
Vol 38 (9-10) ◽  
pp. 181
Author(s):  
Badriul Hegar ◽  
Yvan Vandenplas
Keyword(s):  
Gastric Emptying ◽  
Gastric Motility ◽  
Delayed Gastric Emptying ◽  
Myoelectric Activity ◽  
Gastric Emptying Rate ◽  
Gastric Myoelectric Activity ◽  
Enteric Nerves ◽  
Gastric Muscle ◽  
Abnormal Rate ◽  
Smooth Muscle Contractions

Disorders of gastric motility are generally manifested by an abnormal rate of gastric emptying. The emptying process of the stomach is very complex, and knowledge is limited to the observation that gastric emptying rate is a highly variable phenomenon, and that delayed gastric emptying is frequently the case. The advances in the knowledge of the physiology of gastric muscle and enteric nerves, and the recognition of the patterns of organization of smooth muscle contractions gave a new input to the study of gastric motility. The gastric emptying can be monitored in various ways, such as manometry, scintigraphy, or electrogastrography (EGG). Recently, EGG has received more attention. There is correlation between the EGG signal obtained from body surface electrodes and signals obtained directly from electrodes locates in the gastric muscle (serosal records). Some studies showed an association between EGG-findings and gastric motility disorders, and indicate that EGG is a reliable, non-invasive, useful method to detect gastric myoelectric activity.

Delayed gastric emptying rate in Type 1 diabetics with cardiac autonomic neuropathy

2001 ◽  
Vol 15 (3) ◽  
pp. 128-134 ◽  
Author(s):  
Gassan Darwiche ◽  
Lars-Olof Almér ◽  
Ola Björgell ◽  
Carry Cederholm ◽  
Paul Nilsson
Keyword(s):  
Gastric Emptying ◽  
Autonomic Neuropathy ◽  
Delayed Gastric Emptying ◽  
Cardiac Autonomic Neuropathy ◽  
Gastric Emptying Rate

scholarly journals Quantification of gastric emptying caused by impaired coordination of pyloric closure with antral contraction: a simulation study

2019 ◽  
Vol 16 (157) ◽  
pp. 20190266 ◽  
Author(s):  
Shunichi Ishida ◽  
Taimei Miyagawa ◽  
Gregory O'Grady ◽  
Leo K. Cheng ◽  
Yohsuke Imai
Keyword(s):  
Fluid Dynamics ◽  
Gastric Emptying ◽  
Simulation Study ◽  
Delayed Gastric Emptying ◽  
Bile Reflux ◽  
Retrograde Flow ◽  
Functional Disorders ◽  
Proximal Stomach ◽  
Relaxation Phase ◽  
Peristaltic Contractions

Proper coordination of gastric motor functions is required for healthy gastric emptying. However, pyloric function may be impaired by functional disorders or surgical procedures. Here, we show how coordination between pyloric closure and antral contraction affects the emptying of liquid contents. We numerically simulated fluid dynamics using an anatomically realistic gastrointestinal geometry. Peristaltic contractions in the proximal stomach resulted in gastric emptying at a rate of 3–8 ml min −1 . When the pylorus was unable to close, the emptying rate increased to 10–30 ml min −1 , and instantaneous retrograde flow from the duodenum to the antrum occurred during antral relaxation. Rapid emptying occurred if the pylorus began to open during the terminal antral contraction, and the emptying rate was negative if the pylorus only opened during the antral relaxation phase. Our results showed that impaired coordination between antral contraction and pyloric closure can result in delayed gastric emptying, rapid gastric emptying and bile reflux.

Symptom pattern and gastric emptying rate assessed by the octanoic acid breath test in functional dyspepsia

1998 ◽  
Vol 114 ◽  
pp. A301 ◽  
Author(s):  
J. Tack ◽  
H. Piessevaux ◽  
B. Coulie ◽  
B. Geypens ◽  
P. Caenepeel ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Functional Dyspepsia ◽  
Breath Test ◽  
Octanoic Acid ◽  
Gastric Emptying Rate ◽  
Symptom Pattern

scholarly journals Exogenous and endogenous nitrogen flow rates and level of protein hydrolysis in the human jejunum after [15N]milk and [15N]yoghurt ingestion

1995 ◽  
Vol 74 (2) ◽  
pp. 251-260 ◽  
Author(s):  
Clarie Gaudichon ◽  
Sylvain Mahé ◽  
Nils Roos ◽  
Robert Benamouzig ◽  
Catherine Luengo ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Flow Rate ◽  
Delayed Gastric Emptying ◽  
Gastric Emptying Rate ◽  
Flow Rates ◽  
Significant Stimulation ◽  
Jejunal Tube ◽  
High Level ◽  
Milk Ingestion ◽  
Stimulation Of

Milk and yoghurt proteins were 15N-labelled in order to measure the flow rate of exogenous N during digestion in the human intestine. After fasting overnight, sixteen healthy volunteers, each with a naso-jejunal tube, ingested either [15N]milk (n 7) or [15N]yoghurt (n 9). Jejunal samples were collected every 20 min for 4 h. A significant stimulation of endogenous N secretion was observed during the 20–60 min period after yoghurt ingestion and the 20–40 min period after milk ingestion. The endogenous N flows over a 4 h period did not differ between the groups (44·3 (SEM 6·5) mmol for milk and 63·5 (SEM 5·9) mmol for yoghurt). The flow rates of exogenous N indicated a delayed gastric emptying of the yoghurt N compared with N from milk. The jejunal non-protein N (NPN) flow rate increased significantly after milk and yoghurt ingestion due to an increase in the exogenous NPN flow rate. The NPN fraction of exogenous N ranged between 40 and 80%. The net gastro-jejunal absorption of exogenous N did not differ significantly between milk (56·7 (SEM 8·5)%) and yoghurt (50·9 (SEM 7)%). The high level of exogenous N hydrolysis is in accordance with the good digestibility of milk products. Fermentation modifies only the gastric emptying rate of N and does not affect the level of diet hydrolysis, the endogenous N stimulation or the digestibility rate.

scholarly journals The Effect of Continuous Intake of Lactobacillus gasseri OLL2716 on Mild to Moderate Delayed Gastric Emptying: A Randomized Controlled Study

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1852
Author(s):  
Toshihiro Ohtsu ◽  
Ken Haruma ◽  
Yumiko Ide ◽  
Atsushi Takagi
Keyword(s):  
Placebo Group ◽  
Gastric Emptying ◽  
Odds Ratio ◽  
Delayed Gastric Emptying ◽  
Controlled Study ◽  
Salivary Amylase ◽  
Double Blind ◽  
Gastric Emptying Rate ◽  
Lactobacillus Gasseri ◽  
Liquid Meal

Probiotics have been suggested to be effective for functional dyspepsia, but their effect on gastric motility is not clear. We evaluated the effect of Lactobacillus gasseri OLL2716 (LG21 strain) on mild to moderate delayed gastric emptying by a double-blind, parallel-group, placebo-controlled, randomized trial. Participants (n = 28) were randomly assigned to ingest LG21 strain-containing yogurt (LG21 strain group) or LG21 strain-free yogurt (placebo group) for 12 weeks. The 13C gastric emptying breath test was performed to measure the gastric emptying rate over time following ingestion of a liquid meal, and the time to reach the peak (Tmax) was used as an indicator of gastric emptying. We also measured the salivary amylase concentration, an indicator of autonomic dysfunction under stress. The per-protocol population (n = 27, male n = 4, female n = 23) was evaluated for efficacy. When a ≥30% reduction in the difference between participant’s Tmax and the Japanese mean Tmax was defined as an improvement, the odds ratio of improvement in delayed gastric emptying compared to placebo after 12 weeks was 4.1 (95% confidence interval, 0.8 to 20.2). Moreover, salivary amylase concentrations were significantly lower than in the placebo group, indicating an improvement in autonomic function. The present data were not enough to support the beneficial effects of the LG21 strain on delayed gastric emptying. However, if we define the odds ratio in further study investigated with a larger number of participants, LG21 strain might be expected to have some impact on delayed gastric emptying.

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