Objective: The association of Lower Urinary Tract Symptoms with Metabolic Syndrome in male patients
of age more than 45 years since there is insufcient data about LUTS and MetS in Indian population and
contradicting reports in various studies regarding the correlation of LUTS and MetS worldwide.
Methods- st st 152 men aged >45 years with symptoms of LUTS during a 365 period from 1 June 2019 to 31 May 2020 have been
included in this observational study. LUTS were dened according to the International Prostate Symptom Score (IPSS) and
metabolic syndrome with the National Cholesterol Education Program/Adult Treatment Panel III denition. We studied the
correlation between metabolic syndrome and its individual components, and the severity of LUTS (IPSS and treatment for
LUTS). Analyses were adjusted for body mass index, age, and prostate-specic antigen level.
Results-. About one third of LUTS patients were between 60-69 years of age (33.6%), more than half moderate LUTS
(65.8%)patients. Severe LUTS was most common in age ≥80 years (41.7%). MetS in LUTS patients was 33.6% highest in age 50-
59 years (42.1%) and was lowest in age ≥80 (16.7%). Prevalence of MetS in LUTS patients was 3.63 times higher in age 50-59
years than ≥80 years (OR=3.63, 95%CI=0.89-14.86).
Conclusion- Our results suggest a signicant relationship between LUTS linked to benign prostatic hyperplasia and metabolic
syndrome, in terms of frequency and severity. The risk of being treated for LUTS also increased with an increasing number of
metabolic syndrome components present. The prevention of such modiable factors by the promotion of dietary changes and
regular physical activity practice may be of great importance for public health.
Metabolic Syndrome Components Worsen Lower Urinary Tract Symptoms in Women with Type 2 Diabetes
