Faculty Opinions recommendation of Cardiovascular event reduction versus new-onset diabetes during atorvastatin therapy: effect of baseline risk factors for diabetes.

2014 ◽  
Author(s):  
Wilbert Aronow
Keyword(s):  
Risk Factors ◽  
Cardiovascular Event ◽  
Baseline Risk ◽  
Onset Diabetes ◽  
Therapy Effect ◽  
Atorvastatin Therapy ◽  
New Onset

Cardiovascular Event Reduction Versus New-Onset Diabetes During Atorvastatin Therapy

2013 ◽  
Vol 61 (2) ◽  
pp. 148-152 ◽  
Author(s):  
David D. Waters ◽  
Jennifer E. Ho ◽  
S. Matthijs Boekholdt ◽  
David A. DeMicco ◽  
John J.P. Kastelein ◽  
...  
Keyword(s):  
Cardiovascular Event ◽  
Onset Diabetes ◽  
Atorvastatin Therapy ◽  
New Onset

scholarly journals New-onset diabetes after kidney transplantation: Incidence, risk factors, and outcomes

2016 ◽  
Vol 27 (6) ◽  
pp. 1155 ◽  
Author(s):  
Tariq Ali ◽  
Hassan Aleid ◽  
Ahmad Alhuraiji ◽  
Abdullah Alqaraawi ◽  
Ammar Abdulbaki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Transplantation ◽  
Onset Diabetes ◽  
Incidence Risk ◽  
New Onset

scholarly journals New Onset Diabetes after Transplant – Risk Factors, Clinical Profile and Outcome

2018 ◽  
Vol 2 (1) ◽  
pp. 35-40
Author(s):  
Sakthirajan R ◽  
Dhanapriya J ◽  
Dineshkumar T ◽  
Balasubramaniyan T ◽  
Gopalakrishnan N ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Family History ◽  
Fasting Blood Glucose ◽  
Hcv Infection ◽  
Clinical Profile ◽  
Family History Of Diabetes ◽  
Onset Diabetes ◽  
History Of ◽  
New Onset

Background: New onset diabetes after transplant (NODAT) remains one among the significant threats to both renal allograft and patient survival. The aim of this study was to analyse the clinical profile and risk factors for NODAT.Methods: This prospective observational study involved patients who underwent renal transplantation in our centre between 2010 and 2015.Results: During the mean follow up period of 18 ± 6 months, incidence of NODAT was 26.6% and the cumulativeincidence was highest in the first year after transplant. Recipient age, pre transplant impaired fasting glucose, Hepatitis C virus (HCV) infection, family history of diabetes, tacrolimus, post transplant hypertriglyceridemia and metabolic syndrome were found to be statistically significant risk factors for NODAT. In Cox multivariate regression analysis, age and family history of diabetes were found to be independent risk factors for NODAT. Fasting C-peptide level underlines insulin resistance as predominant mechanism for NODAT in two third of patients. There were higher incidence of urinary tract infection in the NODAT patients. NODAT was found to be an independent risk factor for fungal infection and 10 year cardiovascular risk in the renal recipients. There was no significant impact of NODAT on short term graft and patient survival.Conclusion: Age, pre-transplant fasting blood glucose, family history of diabetes, HCV infection and tacrolimus were found to be the important risk factors, with insulin resistance as the predominant mechanism for NODAT.

scholarly journals An Analysis of the Risk Factors for New-Onset Diabetes Mellitus After Liver Transplantation

2021 ◽  
Vol Volume 14 ◽  
pp. 4783-4792
Author(s):  
Jushan Sun ◽  
Yibiao He ◽  
Lei Bai ◽  
Zhipeng Wang ◽  
Zhu Cao ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Liver Transplantation ◽  
Onset Diabetes ◽  
New Onset Diabetes Mellitus ◽  
New Onset

scholarly journals Risk factors for new-onset diabetes mellitus after distal pancreatectomy

2020 ◽  
Vol 8 (2) ◽  
pp. e001778
Author(s):  
Menghua Dai ◽  
Cheng Xing ◽  
Ning Shi ◽  
Shunda Wang ◽  
Guangdong Wu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Blood Loss ◽  
Distal Pancreatectomy ◽  
College Hospital ◽  
True Rate ◽  
Preoperative Body Mass Index ◽  
Onset Diabetes ◽  
New Onset Diabetes Mellitus ◽  
New Onset

IntroductionSeveral previous studies have reported the incidence of new-onset diabetes mellitus (NODM) after pancreatectomy. Nevertheless, the results were inconsistent. The true rate of NODM after distal pancreatectomy (DP) is still unknown.Research design and methodsThe aim of this study was to investigate the incidence of and the risk factors for NODM after DP. This study enrolled patients who underwent DP between January 2004 and February 2016 at Peking Union Medical College Hospital. Patients with preoperative diabetes mellitus or diagnosed with pancreatic cancer were excluded. The primary outcome was NODM.ResultsA total of 485 patients were enrolled. The median (IQR) of follow-up duration was 30.95 (9.26–180.30) months. The accumulative incidence of NODM was 8.9% at postoperative 6 months, 14.0% at postoperative year one, 22.3% at year three, 27.1% at year five, and 35.5% at year ten. Multivariate analysis showed that the risk of postoperative NODM was positively correlated with age (HR 1.029 (1.013–1.045), p<0.001), preoperative body mass index (BMI) (HR 1.042 (1.003–1.083), p=0.001), operative blood loss (HR 1.0003 (1.0002–1.0010), p<0.001), and length of resected pancreas (HR 1.079 (1.013–1.148), p=0.017). Moreover, concomitant splenectomy (HR 2.001 (1.202–3.331), p=0.008) was associated with significantly higher risk of postoperative NODM.ConclusionNODM incidence increased with postoperative time progression. Age, BMI, surgical blood loss, length of resected pancreas and splenectomy were independent risk factors for NODM after DP.Trial registration numberNCT03030209.

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