Faculty Opinions recommendation of Probiotics and prebiotics in preventing episodes of acute otitis media in high-risk children: a randomized, double-blind, placebo-controlled study.

2013 ◽  
Author(s):  
Direk Limmathurotsakul ◽  
Cherry Lim
Keyword(s):  
High Risk ◽  
Otitis Media ◽  
Acute Otitis Media ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo ◽  
High Risk Children

scholarly journals Specific probiotics in reducing the risk of acute infections in infancy – a randomised, double-blind, placebo-controlled study

2008 ◽  
Vol 101 (11) ◽  
pp. 1722-1726 ◽  
Author(s):  
Samuli Rautava ◽  
Seppo Salminen ◽  
Erika Isolauri
Keyword(s):  
Otitis Media ◽  
Respiratory Infections ◽  
Acute Otitis Media ◽  
Lactobacillus Rhamnosus ◽  
Controlled Study ◽  
First Year ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Recurrent Respiratory Infections ◽  
First Year Of Life

A randomised, double-blind, placebo-controlled study was conducted to determine whether probiotics might be effective in reducing the risk of infections in infancy. Infants requiring formula before the age of 2 months were recruited from community well-baby clinics. Infant formula supplemented with the probioticsLactobacillus rhamnosusGG andBifidobacterium lactisBb-12 or placebo was administered daily until the age of 12 months. Incidence of early infections (before the age of 7 months) and incidence of recurrent (three or more) infections during the first year of life were recorded as the main outcome measures of the study. During the first 7 months of life, seven out of thirty-two (22 %) infants receiving probiotics and twenty out of forty (50 %) infants receiving placebo experienced acute otitis media (risk ratio (RR) 0·44 (95 % CI 0·21, 0·90);P = 0·014) and antibiotics were prescribed for ten out of thirty-two (31 %) infants receiving probiotics and twenty-four out of forty (60 %) infants receiving placebo (RR 0·52 (95 % CI 0·29, 0·92);P = 0·015). During the first year of life, nine out of thirty-two (28 %) infants receiving probiotics and twenty-two out of forty (55 %) infants receiving placebo encountered recurrent respiratory infections (RR 0·51 (95 % CI 0·27, 0·95);P = 0·022). These data suggest that probiotics may offer a safe means of reducing the risk of early acute otitis media and antibiotic use and the risk of recurrent respiratory infections during the first year of life. Further clinical trials are warranted.

Long-Term Antibiotic Treatment of Children with Secretory Otitis Media: A Double-Blind Placebo-Controlled Study

1988 ◽  
Vol 105 (sup449) ◽  
pp. 49-50 ◽  
Author(s):  
J. Thomsen ◽  
J. Sederberg-Olsen ◽  
S. E. Stangerup ◽  
V. Balle ◽  
R. Vejlsgaard
Keyword(s):  
Otitis Media ◽  
Antibiotic Treatment ◽  
Controlled Study ◽  
Secretory Otitis Media ◽  
Double Blind ◽  
Double Blind Placebo

Treatment of acute otitis media with probiotics in otitis-prone children—A double-blind, placebo-controlled randomised study

2007 ◽  
Vol 26 (3) ◽  
pp. 314-321 ◽  
Author(s):  
Katja Hatakka ◽  
Karin Blomgren ◽  
Sara Pohjavuori ◽  
Tarja Kaijalainen ◽  
Tuija Poussa ◽  
...  
Keyword(s):  
Otitis Media ◽  
Acute Otitis Media ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Randomised Study

Treatment of acute otitis media with an antiadhesive oligosaccharide: a randomised, double-blind, placebo-controlled trial

The Lancet ◽  
2000 ◽  
Vol 356 (9239) ◽  
pp. 1398-1402 ◽  
Author(s):  
Pentti Ukkonen ◽  
Kaapo Varis ◽  
Mia Jernfors ◽  
Elja Herva ◽  
Jukka Jokinen ◽  
...  
Keyword(s):  
Otitis Media ◽  
Controlled Trial ◽  
Acute Otitis Media ◽  
Double Blind ◽  
Double Blind Placebo

Respiratory syncytial virus–enriched globulin for the prevention of acute otitis media in high-risk children

1996 ◽  
Vol 129 (2) ◽  
pp. 214-219 ◽  
Author(s):  
E.A.F. Simoes ◽  
J.R. Groothuis ◽  
D.A. Tristram ◽  
K. Allessi ◽  
M.V. Lehr ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
High Risk ◽  
Otitis Media ◽  
Acute Otitis Media ◽  
Syncytial Virus ◽  
High Risk Children
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