Faculty Opinions recommendation of Proteomic changes in rat gastrocnemius muscle after botulinum toxin a injection.

2015 ◽  
Author(s):  
Patrick McNutt ◽  
Phillip Beske ◽  
Kyle Hubbard
Keyword(s):  
Botulinum Toxin ◽  
Gastrocnemius Muscle ◽  
Botulinum Toxin A ◽  
Toxin A

Effects of botulinum toxin A injection and exercise on the growth of juvenile rat gastrocnemius muscle

2002 ◽  
Vol 93 (4) ◽  
pp. 1437-1447 ◽  
Author(s):  
Chen-Ming Chen ◽  
N. Susan Stott ◽  
Heather K. Smith
Keyword(s):  
Botulinum Toxin ◽  
Gastrocnemius Muscle ◽  
Wheel Running ◽  
Botulinum Toxin A ◽  
Voluntary Exercise ◽  
Toxin A ◽  
Cross Sectional ◽  
Supervised Exercise ◽  
Fiber Size ◽  
Early Effects

Botulinum toxin A (Btx) injections and supervised exercise are often used concurrently to treat calf muscle spasticity in children. This study has analyzed the early effects of Btx-induced paralysis and increased activity by voluntary wheel running on cell growth-related processes in juvenile rat gastrocnemius muscle. Btx injection at 29 days of age prevented the normal increases in wet mass (50%) and fiber cross-sectional area (34%) seen by 36 days of age in control rats. Btx-injected vs. contralateral muscles had 22% fewer myonuclei per fiber length but greater than twofold the number of MyoD-positive nuclei at 36 days of age. The accretion of 5-bromo-2′-deoxyuridine-labeled newly produced myonuclei did not differ between limbs. Voluntary exercise during the 7 days increased the mass (18%) and fiber size (23%) of Btx-injected and contralateral muscles but did not affect any other variable. Thus Btx injection and exercise had early effects on muscle and fiber size without consistently associated changes in myonuclear production or number. This suggests the presence of noncontractile activity-dependent, growth-promoting cytoplasmic events in juvenile muscle.

scholarly journals Effect of botulinum toxin A-induced paralysis and exercise training on mechanosensing and signalling gene expression in juvenile rat gastrocnemius muscle

2008 ◽  
Vol 93 (12) ◽  
pp. 1273-1283 ◽  
Author(s):  
Martina Velders ◽  
Kirsten Legerlotz ◽  
Shelley J. Falconer ◽  
N. Susan Stott ◽  
Christopher D. McMahon ◽  
...  
Keyword(s):  
Gene Expression ◽  
Botulinum Toxin ◽  
Exercise Training ◽  
Gastrocnemius Muscle ◽  
Botulinum Toxin A ◽  
Toxin A

Treadmill Exercise Effects In The Gastrocnemius Muscle Following Botulinum Toxin A Injection In A Rat Model

2011 ◽  
Vol 43 (Suppl 1) ◽  
pp. 878
Author(s):  
Sen-Wei Tsai ◽  
Chun-Jung Chen ◽  
Hsiao-Lin Chen ◽  
Chuan-Mu Chen ◽  
Yi-Wen Lin
Keyword(s):  
Botulinum Toxin ◽  
Rat Model ◽  
Gastrocnemius Muscle ◽  
Treadmill Exercise ◽  
Botulinum Toxin A ◽  
Toxin A

scholarly journals Proteomic Changes in Rat Gastrocnemius Muscle After Botulinum Toxin A Injection

2013 ◽  
Vol 37 (2) ◽  
pp. 157 ◽  
Author(s):  
Nami Han ◽  
Hyun Dong Kim ◽  
Mi-Ja Eom ◽  
Jun Myeong You ◽  
Jin Han ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Gastrocnemius Muscle ◽  
Botulinum Toxin A ◽  
Toxin A

Botulinum Toxin A for Aesthetic Contouring of Enlarged Medial Gastrocnemius Muscle

2004 ◽  
Vol 30 (6) ◽  
pp. 867-871 ◽  
Author(s):  
Hyun-Jeong Lee ◽  
Dong-Won Lee ◽  
Yeon-Ho Park ◽  
Mi-Kyung Cha ◽  
Hong-Sik Kim ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Gastrocnemius Muscle ◽  
Botulinum Toxin A ◽  
Medial Gastrocnemius ◽  
Toxin A ◽  
Medial Gastrocnemius Muscle

Classification of Hypertrophic Gastrocnemius Muscle and Its Treatment with Botulinum Toxin A

2019 ◽  
Vol 43 (6) ◽  
pp. 1588-1594
Author(s):  
Wenjun Shi ◽  
Lian Zhu ◽  
Tingliang Wang ◽  
Guoyou Zhang ◽  
Jie Lian
Keyword(s):  
Botulinum Toxin ◽  
Gastrocnemius Muscle ◽  
Botulinum Toxin A ◽  
Toxin A
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