Faculty Opinions recommendation of Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome.

2017 ◽  
Author(s):  
David Teachey
Keyword(s):  
Mtor Pathway ◽  
Autoimmune Lymphoproliferative Syndrome ◽  
Lymphoproliferative Syndrome

scholarly journals Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome

Blood ◽  
2016 ◽  
Vol 128 (2) ◽  
pp. 227-238 ◽  
Author(s):  
Simon Völkl ◽  
Anne Rensing-Ehl ◽  
Andrea Allgäuer ◽  
Elisabeth Schreiner ◽  
Myriam Ricarda Lorenz ◽  
...  
Keyword(s):  
Mitotic Activity ◽  
Proliferative Activity ◽  
Mtor Pathway ◽  
Mtor Signaling ◽  
Autoimmune Lymphoproliferative Syndrome ◽  
Key Points ◽  
High Proliferative Activity ◽  
Lymphoproliferative Syndrome

Key Points ALPS DNT cells and their putative precursors reveal high proliferative activity in vivo, which is associated with hyperactive mTOR signaling. Rapamycin therapy controls mitotic activity and abnormal differentiation of ALPS DNT cells and reduces CD4+ or CD8+ precursor DNT cells.

Bilateral uveitis in a patient with autoimmune lymphoproliferative syndrome

2005 ◽  
Vol 139 (3) ◽  
pp. 562-563 ◽  
Author(s):  
Wee-Kiak Lim ◽  
Roxana Ursea ◽  
Koneti Rao ◽  
Ronald R. Buggage ◽  
Eric B. Suhler ◽  
...  
Keyword(s):  
Autoimmune Lymphoproliferative Syndrome ◽  
Lymphoproliferative Syndrome

scholarly journals Autoimmune Pancreatitis in the Autoimmune Lymphoproliferative Syndrome (ALPS)

Pancreas ◽  
2013 ◽  
Vol 42 (2) ◽  
pp. 363-366 ◽  
Author(s):  
Russell C. Langan ◽  
Fred Gill ◽  
Manish T. Raiji ◽  
John E. Mullinax ◽  
Stefania Pittaluga ◽  
...  
Keyword(s):  
Autoimmune Pancreatitis ◽  
Autoimmune Lymphoproliferative Syndrome ◽  
Lymphoproliferative Syndrome

Adult onset autoimmune lymphoproliferative syndrome due to somatic FAS mutation

2015 ◽  
Vol 45 (4) ◽  
pp. 462-464 ◽  
Author(s):  
G. M. García García ◽  
J. C. Bureo Dacal ◽  
S. Suárez-Varela Pineda ◽  
R. Elduayen Izaguirre
Keyword(s):  
Autoimmune Lymphoproliferative Syndrome ◽  
Adult Onset ◽  
Lymphoproliferative Syndrome
Sign in / Sign up

Export Citation Format

Share Document