Faculty Opinions recommendation of Episymbiotic Saccharibacteria suppresses gingival inflammation and bone loss in mice through host bacterial modulation.

Author(s):  
Marvin Whiteley ◽  
Gina Lewin
1979 ◽  
Vol 6 (4) ◽  
pp. 252-259 ◽  
Author(s):  
B. Kardacihi ◽  
G. N. Wolffe ◽  
J. D. Manson

2020 ◽  
Vol 35 (6) ◽  
pp. 569-578
Author(s):  
Chun Yao ◽  
Qingqing Zhang ◽  
Jun Li ◽  
Peng She ◽  
Fanzhi Kong ◽  
...  

The effect of implantable Zoledronate-PLGA microcapsules (PLGA-ZOL) in periodontitis remains unclear. In this study, we aimed to explore the potential role of PLGA-ZOL in protecting periodontitis and elucidate the underlying mechanism. A rat model of periodontitis was established by ligation the mandibular first molars, then PLGA-ZOL was implanted. The healing volume was scanned by cone-beam computed tomography. Cytokine levels in the gingival tissues were determined by ELISA and RT-PCR. Oxidative stress was indicated by detecting superoxide dismutase concentration and catalase activity. After periodontitis model was successfully established in rats, PLGA-ZOL treatment significantly attenuated alveolar bone loss, as indicated by the increased total healing volume, bone volume/tissue volume and osteoprotegerin level, as well as decreased sRANKL level. PLGA-ZOL treatment also suppressed the inflammatory activities by inhibiting pro-inflammatory cytokine production (TNF-α, IL-1β) but increasing anti-inflammatory cytokine secretion (IL-10). Furthermore, PLGA-ZOL was found to ameliorate oxidative stress in gingival tissues. In conclusion, PLGA-ZOL microcapsules ameliorate alveolar bone loss, gingival inflammation and oxidative stress in an experimental rat model of periodontitis.


2018 ◽  
Vol 20 (11) ◽  
pp. e12891 ◽  
Author(s):  
Nidhish Francis ◽  
Babatunde A. Ayodele ◽  
Neil M. O'Brien-Simpson ◽  
Walter Birchmeier ◽  
Robert N. Pike ◽  
...  

2018 ◽  
Vol 89 (5) ◽  
pp. 577-585 ◽  
Author(s):  
Cüneyt Asım Aral ◽  
Kübra Aral ◽  
Arzu Yay ◽  
Özge Özçoban ◽  
Afig Berdeli ◽  
...  

2019 ◽  
Vol 54 (4) ◽  
pp. 444-452 ◽  
Author(s):  
Lorenzo P. Menzel ◽  
Willam Ruddick ◽  
Mobaswar H. Chowdhury ◽  
David C. Brice ◽  
Ryan Clance ◽  
...  

Author(s):  
Elena Dellepiane ◽  
Maria Menini ◽  
Paolo Canepa ◽  
Paolo Pera

This paper presents a case report where the influence of plaque accumulation and overload on a dental implant was observed. The patient presented crown loss on one implant affected by peri-implant bone resorption and gingival inflammation associated with poor oral hygiene. After 12 months a single crown was delivered, but as soon as the occlusal load was applied bone loss and implant failure occurred. In the present case report the dental implant remained stable as long as the implant was not loaded, although a 100% plaque index and bleeding on probing were present during the entire followup period. In contrast, as soon as an occlusal load was applied periimplant bone loss and implant failure occurred. These observations suggest that plaque accumulation alone is not a triggering factor for peri-implant bone loss and implant failure. On the contrary, occlusal load, when not properly controlled, might cause bone resorption.


2020 ◽  
Vol 20 (6) ◽  
pp. 1-1
Author(s):  
Shengdan Zhang ◽  
Yulong Niu ◽  
Zhuo Yang ◽  
Yuwei Zhang ◽  
Qiang Guo ◽  
...  

Author(s):  
Celine Hestiana ◽  
Ria Noerianingsih Firman ◽  
Deddy Firman

Pendahuluan: Radiografi periapikal dapat digunakan untuk mendeteksi tulang alveolar pada perawatan gigi tiruan jembatan. Pembuatan gigi tiruan jembatan harus memenuhi syarat-syarat biologis. Apabila adaptasi marginal buruk, penempatan margin intracrevicular terlalu dalam, permukaan restorasi yang kasar dan restorasi yang overkontur dapat menyebabkan peradangan lokal seperti inflamasi gingiva, peningkatan kedalaman probing dan kehilangan tulang alveolar. Tujuan penelitian ini untuk mengetahui bagaimana deskripsi tulang alveolar pasca perawatan jembatan di RSGM UNPAD ditinjau dari radiografi periapikal. Metode: Jenis penelitian deskriptif dengan populasi adalah seluruh hasil radiograf periapikal pada pasien sebelum dan sesudah perawatan jembatan posterior yang datang ke RSGM Unpad dan sampel adalah radiograf sebelum dan sesudah perawatan jembatan posterior sebanyak 17 pasien setelah insersi 1 minggu dan 2 pasien setelah insersi 4 minggu. Pengukuran ketinggian tulang alveolar menggunakan Metode Proksimal RABL (Radiographic Alveolar Bone Loss) yang dihitung memakai jangka sorong. Hasil : Kehilangan tulang alveolar setelah insersi 1 minggu pada mesial dan distal yaitu 0,003 mm, setelah insersi 2 minggu 0,007 mm pada mesial dan 0,025 pada distal,setelah insersi 3 minggu 0,025 mm pada mesial dan 0,019 mm pada distal, setelah insersi 4 minggu 0,075 mm mesial dan 0,063 mm distal. Simpulan: Pasca perawatan jembatan, ditinjau dari radiografi periapikal, terdapat kehilangan tulang alveolar ringan berdasarkan metode proksimal RABL.Kata kunci : Gigi tiruan jembatan, radiograf periapikal, tulang alveolar. ABSTRACTIntroduction: Periapical radiography can be used to detect alveolar bone in bridge denture treatment. The making of bridge denture must fulfil biological requirements. Poor marginal adaptation will lead to deeper intracrevicular margin placement, rough surfaces, over contour restoration can cause local inflammation such as gingival inflammation, increased probing depth and alveolar bone loss. The purpose of this research was to know the description of alveolar bone after bridge denture treatment reviewed through periapical radiography. Methods: This research was descriptive with the population of all radiograph periapical treatment of posterior bridge in Universitas Padjadjaran Dental Hospital and the sample was radiograph periapical before and after bridge treatment of as much as 17 patients after 1-week insertion and 2 patients after 4-weeks insertion.  Alveolar bone height measurements was carried out using the RABL (Radiographic Alveolar Bone Loss) proximal method calculated using the Vernier callipers. Results: The results indicated that alveolar bone loss occurred after 1-week insertion on the mesial and distal was 0.003 mm; after 2-weeks insertion was 0.007 mm on the mesial and 0.025 mm on the distal; after 3-weeks insertion was 0.025 mm on the mesial and 0.019 mm on the distal; and after 4-weeks insertion was 0.075 mm on the mesial and 0.063 mm on the distal. Conclusion: Post bridge treatment, in terms of periapical radiography, found a mild alveolar bone loss based on the proximal RABL method.  Keywords: Bridge denture, periapical radiograph, alveolar bone.


1996 ◽  
Vol 13 (3) ◽  
pp. 101-105 ◽  
Author(s):  
Colin E. Harvey ◽  
Frances S. Shofer ◽  
Larry Laster

In 1350 client-owned dogs in North America, the association of calculus, gingival inflammation and periodontal bone loss with diet (dry food only, or other than dry food only), and with access to other chewing materials was analyzed. There were few apparent differences seen in dogs fed dry food only compared with those fed other than dry food only. There was progressively less accumulation of calculus, less gingival inflammation and less periodontal bone loss in dogs that were given access to more types of chewing materials (rawhides, bones, biscuits, chew toys) compared with dogs given access to fewer or no chewing materials. When the effects of individual chewing materials were analyzed, access to rawhides overall had the greatest apparent periodontal protective effect, and this effect was more apparent in dogs fed dry food only compared with those fed other than dry food only.


Author(s):  
Otari Chipashvili ◽  
Daniel R. Utter ◽  
Joseph K. Bedree ◽  
Yansong Ma ◽  
Fabian Schulte ◽  
...  

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