Variation of system performance, quality control standards and adherence to international FDG-PET/CT imaging guidelines

2014 ◽  
Vol 53 (06) ◽  
pp. 242-248 ◽  
Author(s):  
H. Bergmann ◽  
B. Geist ◽  
M. Schaffarich ◽  
A. Hirtl ◽  
M. Hacker ◽  
...  

Summary Aim: To gather information on clinical operations, quality control (QC) standards and adoption of guidelines for FDG-PET/CT imaging in Austrian PET/CT centres. Methods: A written survey composed of 68 questions related to A) PET/CT centre and installation, B) standard protocol parameters for FDG-PET/CT imaging of oncology patients, and C) standard QC procedures was conducted between November and December 2013 among all Austrian PET/CT centres. In addition, a NEMA-NU2 2012 image quality phantom test was performed using standard whole-body imaging settings on all PET/CT systems with a lesion-to- background ratio of 4. Recovery coefficients (RC) were calculated for each lesion and PET/ CT system. Resu lts: A) 13 PET/CT systems were installed in 12 nuclear medicine departments at public hospitals. B) Average fasting prior to FDG-PET/CT was 7.6 (4-12) h. All sites measured blood glucose levels while using different cut-off levels (64%: 150 mg/dl). Weight- based activity injection was performed at 83% sites with a mean FDG activity of 4.1 MBq/kg. Average FDG uptake time was 55 (45-75) min. All sites employed CT contrast agents (variation from 1 %-95% of the patients). All sites reported SUV-max. C) Frequency of QC tests varied significantly and QC phantom measurements revealed significant differences in RCs. Conclusion: Significant variations in FDG-PET/CT protocol parameters among all Austrian PET/CT users were observed. subsequently, efforts need to be put in place to further standardize imaging protocols. At a minimum clinical PET/CT operations should ensure compliance with existing guidelines. Further, standardized QC procedures must be followed to improve quantitative accuracy across PET/CT centres.

2013 ◽  
Vol 34 (6) ◽  
pp. 540-543 ◽  
Author(s):  
Kuruva Manohar ◽  
Anish Bhattacharya ◽  
Bhagwant R. Mittal
Keyword(s):  
Fdg Pet ◽  
Pet Ct ◽  
18F Fdg ◽  

Author(s):  
Almalki Yassir

Abstract Background Leydig cell tumors (LCTs) represent the most common form of stromal tumors. We reported the 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) findings of a patient with testicular LCT. Case presentation A 50-year-old man with a history of end-stage renal disease and renal transplantation 19 years ago. One year earlier, he started to have a chronic rejection. During the investigation to determine the cause of chronic rejection, a suspicious lesion in the graft with a collection around it was seen on ultrasound (US) images, raising the possibility of post-transplant lymphoproliferative disorder (PTLD). The patient was referred for further evaluation by whole body 18F-FDG PET/CT imaging. The image finding revealed an incidental hypermetabolic focal lesion in the right testicle—no other specific findings in the remaining parts of the body nor definitive FDG avid lymphadenopathy to suggest PTLD. Testicular US was requested and showed a well-defined right-sided heterogeneous hypoechoic intratesticular focal mass at the upper pole of the right testis with significant internal vascularity on the color Doppler imaging. The patient underwent a right radical orchidectomy, and the tumor was pathologically confirmed as an LCT. Conclusion In our case, 18F-FDG-PET/CT has been helpful in incidentally detecting this rare testicular tumor in a patient with suspected PTLD.


2018 ◽  
Vol 56 ◽  
pp. 264
Author(s):  
F. Zito ◽  
A. D’Alessio ◽  
A. Pira ◽  
M.F. Bardo ◽  
R. Benti

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 7186-7186
Author(s):  
D. Lardinois ◽  
H. C. Steinert ◽  
M. Tutic ◽  
G. Görres ◽  
R. Stahel ◽  
...  

2006 ◽  
Vol 31 (7) ◽  
pp. 398-400 ◽  
Author(s):  
Peeyush Bhargava ◽  
Ching-Wen Angela Chang ◽  
Barbara Glickman ◽  
Gabriel Sara ◽  
Munir Ghesani

2011 ◽  
Vol 38 (8) ◽  
pp. 1459-1468 ◽  
Author(s):  
Jong-Ryool Oh ◽  
Byung-Hyun Byun ◽  
Sun-Pyo Hong ◽  
Ari Chong ◽  
Jahae Kim ◽  
...  

2015 ◽  
Author(s):  
Jenna Deakin ◽  
Michelle Siu ◽  
Harriet Cunningham ◽  
Nikhil Patel ◽  
Thomas Osborne ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Pet Ct ◽  
18F Fdg ◽  

2008 ◽  
Vol 47 (02) ◽  
pp. 73-79 ◽  
Author(s):  
U. Pietrzyk ◽  
C. Knoess ◽  
S. Vollmar ◽  
K. Wienhard ◽  
L. Kracht ◽  
...  

SummaryWe investigated the efficacy of combined FDG-PET/CT imaging for the diagnosis of small-size uveal melanomas and the feasibility of combining separate, high-resolution (HR) FDG-PET with MRI for its improved localization and detection. Patients, methods: 3 patients with small-size uveal melanomas (0.2–1.5 ml) were imaged on a combined whole-body PET/CT, a HR brain-PET, and a 1.5 T MRI. Static, contrast-enhanced FDG-PET/CT imaging was performed of head and torso with CT contrast enhancement. HR PET imaging was performed in dynamic mode 0–180 min post-injection of FDG. MRI imaging was performed using a high-resolution small-loop-coil placed over the eye in question with T2–3D-TSE and T1–3D-SE with 18 ml Gd-contrast. Patients had their eyes shaded during the scans. Lesion visibility on high-resolution FDGPET images was graded for confidence: 1: none, 2: suggestive, 3: clear. Mean tumour activity was calculated for summed image frames that resulted in confidence grades 2 and 3. Whole-body FDG-PET/CT images were reviewed for lesions. PET-MRI and PET/ CT-MRI images of the head were co-registered for potentially improved lesion delineation. Results: Whole-body FDG-PET/CT images of 3/3 patients were positive for uveal melanomas and negative for disseminated disease. HR FDG-PET was positive already in the early time frames. One patient exhibited rising tumour activity with increasing uptake time on FDG-PET. MRI images of the eye were co-registered successfully to FDG-PET/CT using a manual alignment approach. Conclusions: Small-size uveal melanomas can be detected with whole-body FDG-PET/CT. This feasibility study suggests the exploration of HR FDG-PET in order to provide additional diagnostic information on patients with uveal melanomas. First results support extended uptake times and high-sensitivity PET for improved tumour visibility. MRI/PET co-registration is feasible and provides correlated functional and anatomical information that may support alternative therapy regimens.


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