scholarly journals Millimeter-Wave Bat for Mapping and Quantifying Micromotions in Full Field of View

Research ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Yuyong Xiong ◽  
Songxu Li ◽  
Changzhan Gu ◽  
Guang Meng ◽  
Zhike Peng
Keyword(s):  
Millimeter Wave ◽  
Laser Scanning ◽  
Wide Spectrum ◽  
Mechanical Vibration ◽  
Phase Evolution ◽  
Field Of View ◽  
Vibration Measurement ◽  
Full Field ◽  
Cluttered Environments ◽  
Visual Sensing

Echolocating bats possess remarkable capability of multitarget spatial localization and micromotion sensing in a full field of view (FFOV) even in cluttered environments. Artificial technologies with such capability are highly desirable for various fields. However, current techniques such as visual sensing and laser scanning suffer from numerous fundamental problems. Here, we develop a bioinspired concept of millimeter-wave (mmWave) full-field micromotion sensing, creating a unique mmWave Bat (“mmWBat”), which can map and quantify tiny motions spanning macroscopic to μm length scales of full-field targets simultaneously and accurately. In mmWBat, we show that the micromotions can be measured via the interferometric phase evolution tracking from range-angle joint dimension, integrating with full-field localization and tricky clutter elimination. With our approach, we demonstrate the capacity to solve challenges in three disparate applications: multiperson vital sign monitoring, full-field mechanical vibration measurement, and multiple sound source localization and reconstruction (radiofrequency microphone). Our work could potentially revolutionize full-field micromotion monitoring in a wide spectrum of applications, while may inspiring novel biomimetic wireless sensing systems.

scholarly journals Feasibility of peripheral OCT imaging using a novel integrated SLO ultra-widefield imaging swept-source OCT device

2021 ◽  
Author(s):  
Simrat K. Sodhi ◽  
John Golding ◽  
Carmelina Trimboli ◽  
Netan Choudhry
Keyword(s):  
Posterior Pole ◽  
Field Of View ◽  
Retinal Diseases ◽  
Swept Source ◽  
Full Field ◽  
Swept Source Oct ◽  
Oct Imaging ◽  
Field Device ◽  
Areas Of Interest ◽  
Retinal Pathologies

Abstract Purpose To describe the feasibility of peripheral OCT imaging in retinal diseases using a novel full-field device. Methods A total of 134 consecutive eyes were referred and imaged on the Optos Silverstone swept-source OCT (SS-OCT) (Optos PLC; Dunfermline, UK). Scanning laser ophthalmoscope (SLO) images and the associated SS-OCT images were obtained in the posterior pole, mid-periphery or far periphery based on the nature of the referral and on new areas of interest observed in the optomap images at the time of imaging. Results A total of 134 eyes (96 patients) were enrolled in the study. One hundred and twenty-five eyes (91 patients) with 38 retinal pathologies were prospectively assessed and 9 eyes (5 patients) were excluded due to incomplete image acquisition. The average age of the subjects was 54 years (range 21–92 years). Thirty-nine out of 125 eyes (31%) had macular pathologies. Eighty-six out of 125 eyes (69%) had peripheral only pathologies, an area which cannot be visualized by standard OCT devices with a 50 degree field-of-view. Conclusions The ability to capture peripheral pathologies using an integrated SLO-UWF imaging with full-field swept-source provided high-grade anatomical insight that confirmed the medical and surgical management in a majority of cases. Its use in the mid- and far periphery provides a holistic clinical picture, which can potentially aid in the understanding of various retinal pathologies.

scholarly journals Mild Clinical Presentation of Joubert Syndrome in a Male Adult Carrying Biallelic MKS1 Truncating Variants

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1218
Author(s):  
Raffaella Brunetti-Pierri ◽  
Marianthi Karali ◽  
Francesco Testa ◽  
Gerarda Cappuccio ◽  
Maria Elena Onore ◽  
...  
Keyword(s):  
Wide Spectrum ◽  
Clinical Manifestations ◽  
Brain Magnetic Resonance Imaging ◽  
Joubert Syndrome ◽  
Male Adult ◽  
Full Field ◽  
Pathogenic Variants ◽  
Disease Spectrum ◽  
Male Individual ◽  
The Central Nervous System

Pathogenic variants in the MKS1 gene are responsible for a ciliopathy with a wide spectrum of clinical manifestations ranging from Meckel and Joubert syndrome (JBTS) to Bardet-Biedl syndrome, and involving the central nervous system, liver, kidney, skeleton, and retina. We report a 39-year-old male individual presenting with isolated Retinitis Pigmentosa (RP), as assessed by full ophthalmological evaluation including Best-Corrected Visual Acuity measurements, fundus examination, Goldmann Visual Field test, and full-field Electroretinography. A clinical exome identified biallelic nonsense variants in MKS1 that prompted post-genotyping investigations for systemic abnormalities of ciliopathy. Brain magnetic resonance imaging revealed malformations of the posterior cranial fossa with the ‘molar tooth sign’ and cerebellar folia dysplasia, which are both distinctive features of JBTS. No other organ or skeletal abnormalities were detected. This case illustrates the power of clinical exome for the identification of the mildest forms of a disease spectrum, such as a mild JBTS with RP in the presented case of an individual carrying biallelic truncating variants in MKS1.

Full field of view super-resolution imaging based on two static gratings and white light illumination

2008 ◽  
Vol 47 (17) ◽  
pp. 3080 ◽  
Author(s):  
Javier García ◽  
Vicente Micó ◽  
Dan Cojoc ◽  
Zeev Zalevsky
Keyword(s):  
White Light ◽  
Super Resolution ◽  
Field Of View ◽  
Light Illumination ◽  
Full Field ◽  
Resolution Imaging ◽  
White Light Illumination
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