scholarly journals Primary Renal Squamous Cell Carcinoma: An Unusual Malignancy

2019 ◽  
Vol 8 (1) ◽  
pp. 50-53
Author(s):  
Huma Mushtaq ◽  
Naima Tariq ◽  
Tehreem Atif ◽  
Saeed Alam ◽  
Mumtaz Ahmed
Keyword(s):  
Squamous Cell Carcinoma ◽  
Urinary Tract ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Case Reports ◽  
Left Kidney ◽  
Upper Urinary Tract ◽  
Male Resident ◽  
Renal System ◽  
Azad Kashmir

Malignancies of the upper urinary tract are rare, accounting for about 8% of all malignancies of the renal system, presenting mostly as urothelial carcinoma. Squamous cell carcinoma (SCC) arising from the upper urinary tract is even more rare, accounting for about 0.5% of all malignancies of the renal system and 10% of all renal pelvic tumors. There are very few case reports in the indexed literature regarding renal squamous cell carcinoma. Here we present a case of SCC arising from the lower pole of left kidney, in a 35-year-old male resident of Muzaffarabad, Azad Kashmir.

scholarly journals Ureteral urothelial carcinoma with squamous cell carcinoma and sarcomatoid carcinoma differentiation: a case report

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shangqing Ren ◽  
Hualin Feng ◽  
Yige Bao ◽  
Yi Wei ◽  
Yong Ou ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Standard Treatment ◽  
Clinical Manifestations ◽  
Sarcomatoid Carcinoma ◽  
Upper Urinary Tract ◽  
Malignant Tumours

Abstract Background Upper urinary tract urothelial carcinoma (UTUC) with multiple pathological types is extremely rare in the clinic, but the recurrence rate and mortality these patients are high. At present, there is no standard treatment for such cases. Case presentation We reported a case of ureteral urothelial carcinoma with squamous cell carcinoma and sarcomatoid carcinoma differentiation and rapid ileal metastasis and reviewed the literature related to different pathological types of upper urinary tract tumours to explore the diagnosis, treatment and prognosis characteristics of the disease, enhance our understanding of its clinical manifestations and history of evolution and provide guidance for avoiding missed diagnosis and misdiagnosis. Conclusion There is no standard treatment for urinary malignant tumours with multiple pathological types; radical surgery is considered a suitable choice. Chemotherapy, targeted drug therapy and immunotherapy may be beneficial to the survival of patients. In short, these patients have a high risk of recurrence and metastasis and a poor prognosis.

scholarly journals TWO CASES OF SQUAMOUS CELL CARCINOMA OF UPPER URINARY TRACT WITH HYPERCALCEMIA

2008 ◽  
Vol 99 (6) ◽  
pp. 703-708
Author(s):  
Satoshi Washino ◽  
Fumihito Terauchi ◽  
Atsushi Matsuzaki ◽  
Yutaka Kobayashi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Urinary Tract ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Upper Urinary Tract

scholarly journals Treatment of primary squamous cell carcinoma of the upper urinary tract

Cancer ◽  
1991 ◽  
Vol 68 (12) ◽  
pp. 2575-2578 ◽  
Author(s):  
Ofer Nativ ◽  
Herbert M. Reiman ◽  
Michael M. Lieber ◽  
Horst Zincke
Keyword(s):  
Squamous Cell Carcinoma ◽  
Urinary Tract ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Upper Urinary Tract ◽  
Primary Squamous Cell Carcinoma

scholarly journals Rare case of upper urinary tract squamous cell carcinoma presenting with significant paraneoplastic syndrome

2020 ◽  
Vol 12 (4) ◽  
pp. 388
Author(s):  
SandraS.Y. Kim ◽  
RicardoA Rendon ◽  
Myuran Thana ◽  
Lori Wood ◽  
Cheng Wang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Urinary Tract ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Paraneoplastic Syndrome ◽  
Rare Case ◽  
Upper Urinary Tract

scholarly journals Bladder squamous cell carcinoma in a pregnant woman: case report and review of the literature

BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Pablo A. Rojas ◽  
Cristián González ◽  
Gonzalo P. Mendez ◽  
Alejandro Majerson ◽  
Ignacio F. San Francisco
Keyword(s):  
Squamous Cell Carcinoma ◽  
Bladder Cancer ◽  
Pregnant Woman ◽  
Urinary Tract ◽  
Cell Carcinoma ◽  
Radical Cystectomy ◽  
Squamous Cell ◽  
Pet Ct ◽  
Cell Bladder Cancer ◽  
Urinary Tract Reconstruction

Abstract Background Bladder tumors in pregnancy are extremely rare. No more than 50 cases have been published to date, including all histologic variants, and only three cases of bladder squamous cell carcinoma have been described. Case presentation We present a clinical case of a 31-year-old woman with bladder squamous cell carcinoma in the second trimester of pregnancy. After a C-section at 30 weeks, we performed radical cystectomy with extended bilateral lymphadenectomy, hysterectomy and right oophorectomy. The Studer neobladder technique was performed for urinary tract reconstruction. Definitive pathology showed invasive bladder squamous cell carcinoma, Grade 2, with microscopic infiltration of the perivesical fat, negative margins, and 3/28 lymph nodes with carcinoma (pT3aN2M0). The patient underwent 18 months of surveillance after radical cystectomy, without recurrence by PET-CT. Conclusions Bladder cancer in pregnant women is extremely rare but must be considered in those with recurrent gross hematuria and/or recurrent urinary tract infection. To our knowledge, this case involves the longest recurrence-free survival of a pregnant woman with squamous cell bladder cancer published thus far.

scholarly journals Cutaneous Squamous Cell Carcinoma in Patients with Hidradenitis Suppurativa

Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1153
Author(s):  
Elysia Racanelli ◽  
Abdulhadi Jfri ◽  
Amnah Gefri ◽  
Elizabeth O’Brien ◽  
Ivan Litvinov ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Hidradenitis Suppurativa ◽  
Case Reports ◽  
Rare Complication ◽  
Cox Proportional Hazards ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Statistical Hypothesis ◽  
Statistical Hypothesis Testing

Background: Cutaneous squamous cell carcinoma (cSCC) is a rare complication of hidradenitis suppurativa (HS). Objectives: To conduct a systematic review and an individual patient data (IPD) meta-analysis to describe the clinical characteristics of HS patients developing cSCC and determine predictors of poor outcome. Methods: Medline/PubMed, Embase, and Web of Science were searched for studies reporting cSCC arising in patients with HS from inception to December 2019. A routine descriptive analysis, statistical hypothesis testing, and Kaplan–Meier survival curves/Cox proportional hazards regression models were performed. Results: A total of 34 case reports and series including 138 patients were included in the study. The majority of patients were males (81.6%), White (83.3%), and smokers (n = 22/27 reported) with a mean age of 53.5 years. Most patients had gluteal (87.8%), Hurley stage 3 HS (88.6%). The mean time from the diagnosis of HS to the development of cSCC was 24.7 years. Human papillomavirus was identified in 12/38 patients tested. Almost 50% of individuals had nodal metastasis and 31.3% had distant metastases. Half of the patients succumbed to their disease. Conclusions: cSCC is a rare but life-threatening complication seen in HS patients, mainly occurring in White males who are smokers with severe, long-standing gluteal HS. Regular clinical examination and biopsy of any suspicious lesions in high-risk patients should be considered. The use of HPV vaccination as a preventive and possibly curative method needs to be explored.

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